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alpha 2 agonist(presynaptic ganglion)
decreases NE release
-must taper remove to avoid rebound HTN
I: drug withdrawal and HTN
SE: sedation, dry mouth |
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Definition
noncompetitive, irreversible, and non-selective (a1 and a2) a-antagonist
I: pheochromocytoma
SE: orthostatic hypotension, reflex tachycardia
CI: coronary perfusion |
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non-selective a-antagonists
I: pheochromocytoma, impotence
SE: hypotension, reflex tachycardia, arrythmias, angina
CI: decreased coronary perfusion |
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non-selective a-antagonist
veterinary medicine |
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Definition
alpha 1 selective antagonist
I: HTN, Raynaud's disease
SE: dizziness, orthostatic hypotension, tachycardia, palpitations |
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B1=B2 agonist
I: emergency stimulation of heart |
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Definition
B1>>B2 agonist
increase inotropic but not chronotropic
increases cAMP and increased Ca+2
I: cardiogenic shock (acute CHF) |
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B2>>B1 agonist
I: reduce premature uterine contractions |
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B2>>B1 agonist
I: asthma, bronchospasm, COPD
SE: shakiness, tumor when it loses selectivity |
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Definition
B2>>B1 agonist
I: asthma, bronchospasm, COPD |
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Definition
non-selective B antagonist
I: migraine prophylaxis |
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Definition
non-selective B antagonist
like propranolol |
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Non-selective B antagonist
decreased production of aqueous humor by ciliary body
I: glaucoma (good b/c it only has effect on ciliary bodies) |
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a and B antagonist
I: CHF and HTN
MAO: decreases lipid peroxidation and vascular wall thickening |
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Definition
a and B antagonist
2nd line in pregnancy for HTN (a-methyldopa is 1st) |
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Definition
a=b agonist
I: anaphylaxis and cardiac arrest
SE: CNS, hemorrhage, tachycardia
decreases diastolic pressure |
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Definition
B>a agonist
MOA: releases stores of NE and weakly stimulates receptors
SE: HTN, cardiac stimulation |
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Definition
MAO: increases renal perfusion
I: cardiogenic and septic shock
Low- D1 renal dilation
Higher- B1
Highest- A1 |
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Term
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Definition
MOA: A and B agonist and blocks reuptake
I: ADD, ADHA, narcolepsy, appetite control |
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Definition
MOA: blocks Na/K ATPase reuptake of monoamines
I: local anesthetic |
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Definition
MOA: converted to methyl-NE and a2 agonist
I: HTN and pregnancy
SE: sedation |
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Definition
blocks Mg/ATP dependent transport into storage vesicles
SE: severe mental depression |
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Definition
stimulates release of stored catecholamines
found in food |
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Definition
| blocks the release of stored NE |
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Definition
muscarinic agonist
I: glaucoma
MOA: increases outflow of the aqueous humor |
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