Term
| *Phenoxybenzamine *Phentolamine |
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Definition
| Nonselective alpha antagonist *Phenoxybenzamine- used for pheocromocytoma, otherwise can get large reflex tachycardia |
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Term
| Doxazosin *Prazosin Alfuzosin *Tamsulosin Terazosin Yohimbine |
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Definition
| α1 selective antagonist (caution: arrythmias- sudden death) Use: hypertension treatment, CHF, low tachycardia SE: syncope *Prazosin (and Afusozin)- BPH (blocks a1A receptor)- SE: syncope 1st admin and inc dosages *Tamsulosin- a1-D spec, urinary tract-->micturition, less orth hypo then other "-zosin" drugs -Favorable effect: INC HDL/LDL ratio (lowers serum lipids)- so lowers cholesterol without lowering HDL :) |
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Term
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Definition
| Nonselective beta antagonist *Propranolol- low dose for performance anxiety *Pindolol- good for hypertensive patients with bradycardia or exercise intolerance |
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Term
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Definition
| Nonselective ß, α1 blocker (antagonist) **potent anti-hypertensive, CAN be used during EMERGENCIES |
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Term
| Acebutolol, Metoprolol, *Atenolol, Bisoprolol, Esmolol |
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Definition
| *ß1 (cardio-) selective antagonist |
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Term
| Tubocurarine, Atracurium, Mivacurium, Vecuronium |
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Definition
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Term
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Definition
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Term
Baclofen
Dantrolene
Tizanidine |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
MOA: DEC Renin, DEC CO
SE
* withdrawl syndrome: rebound tachycardia
-airway toxicity (bronchoconstriction)
-Augments hypoglycemia in insulin dep patients- masks the tachycardia associated with hypoglycemia
-INC TG and LDL, DEC HDL
-NSAIDS may block HT effects
use other HT drugs first unless patient has heart issues then use beta blocker |
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