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ANS 3440 Gluconeogenesis
Gluconegenesis
25
Agriculture
Undergraduate 3
03/24/2014

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Term
What is an emergency pathway in non ruminants to make glucose and in ruminants this is done all the time?
Definition
Gluconeogenesis
Term
Gluconeogenesis is the reverse of what?
Definition
Glycolysis
Term
What 3 steps are different in Gluconeogenesis?
Definition
Cannot go from pyruvate directly to PEP, A different enzyme b/w fructose 1,6 Bisphosphate and fructose 6 phosphate, and Different enzyme b/w glucose 6 phosphate and glucose
Term
What is the site of gluconeogenesis?
Definition
Liver
Term
What is amino acid disproportion?
Definition
Non ideal amino acid pattern
Term
What is the indigestion of large quantities of an individual amino acid?
Definition
Toxicity
Term
Cannot get toxicity by just ingesting protein but can also get toxicity from inborn errors of what?
Definition
Metabolism
Term
What are 3 relative toxicities?
Definition
Sulfur containing AA, Basic amino acids, and Branched chain AA
Term
What is growth depression due to excessive amounts of one amino acid that can be alleviated by a structurally similar amino acid?
Definition
Antagonism
Term
What is adverse effects from additions or surpluses of essential amino acids other than the ont that is first limiting that was created by the formulator?
Definition
Imbalance
Term
Protein is a dynamic tissue that is constantly undergoing what 2 processes?
Definition
Breakdown and Synthesis
Term
If protein synthesis is greater that protein breakdown then what is occurring?
Definition
Protein accretion (positive nitrogen balance)
Term
If protein synthesis is less than protein breakdown then what is occurring?
Definition
Protein degradation (negative nitrogen balance)
Term
The metabolic pool of amino acids is located where?
Definition
In Cytoplasm
Term
Metabolic pool of amino acids contains 80% amino acids from what?
Definition
Turnover
Term
Contribution of amino acids to the pool is much larger from what than from the diet?
Definition
Breakdown
Term
What measures protein turnover?
Definition
Fractional Synthesis Rates (FSR)
Term
FSR is the percentage of the protein in an organ/tissue that is synthesized per what?
Definition
Day
Term
What organ/tissue has the largest FSR%?
Definition
SI Mucosa 136%
Term
What organ/tissue is the 2nd largest FSR%?
Definition
Liver 87%
Term
What organ/tissue is the 3rd largest FSR%?
Definition
Kidney 48%
Term
What organ/tissue has a FSR% of 17%?
Definition
Heart and Brain
Term
What organ/tissue has the lowest FSR%?
Definition
Muscle 13%
Term
What percent of maintenance energy is expended just for protein turnover?
Definition
25-33%
Term
Why is protein turnover necessary?
Definition
Restructuring muscle tissue, Cell and tissue repair, Enzyme and hormone production, anitbodies
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