Term 
        
        | At what life stage does a dairy cow have the highest mortality risk? Morbidity? |  
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        Definition 
        
        | Pre-weaning calves are at the greatest risk of morbidity and mortality |  
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        Term 
        
        | What are the major causes of calf morbidity pre-weaning? |  
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        Definition 
        
        Diarrhea / Digestive (~60%) Respiratory (~32%) Navel (4%)  Other (2%) |  
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        Term 
        
        | What are the major causes of calf mortality pre-weaning? |  
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        Definition 
        
        Diarrhea / Digestive (56%) Respiratory (22%) Unknown (8%) Calving (5%) Miscellaneous (5%) Joint / Navel (2%) Injury (2%) |  
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        Term 
        
        | What is the average rate of pre-weaning mortality? |  
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        Definition 
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        Term 
        
        | What are the 5 C's of successful calf rearing? |  
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        Definition 
        
        Colostrum Cleanliness Consistency Calories Comfort |  
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        Term 
         | 
        
        
        Definition 
        
        | bacteria in the bloodstream |  
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        Term 
        
        | What are some of the important diseases of dairy calves? |  
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        Definition 
        
        neonatal calf diarrhea pneumonia septicemia navel omphalophlebitis (umbilical inflammation) umbilical hernia |  
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        Term 
        
        | What is passive transfer of immunity? Why is it important? |  
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        Definition 
        
        post-natal transfer of antibodies from cow to calf via colostrum
  important because antibodies are too large to cross the placenta in ruminants, and they are essential as  they bind to & help remove pathogens |  
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        Term 
        
        | What are the important qualities/considerations regarding colostrum? (4) |  
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        Definition 
        
        Quantity Quality Quickness Cleanliness |  
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        Term 
         | 
        
        
        Definition 
        
        | the first milk produced by the cow, rich in nutrients and immunoglobulins |  
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        Term 
        
        | What factors affect the quality of colostrum? |  
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        Definition 
        
        Vaccination Nutrition of dam Heat stress Leaking Cleanliness of harvest Volume (roughly inversely proportional) |  
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        Term 
        
        Rank the following in order of the quality of colostrum they produce:
  Mature dairy Dairy heifers Beef cattle |  
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        Definition 
        
        | Beef Cattle > Mature Dairy > Dairy Heifers |  
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        Term 
        
        | How can you test quality of colostrum? |  
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        Definition 
        
        Specific gravity (colostrometer)
  Ig / total protein in calf serum (1-7 days old) |  
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        Term 
        
        | What is the minimum amount of IgG you should aim to have delivered to a calf via colostrum? |  
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        Definition 
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        Term 
        
        | What minimum volume of colostrum should a calf ingest in their first 24h of life in order to absorb enough IgG? |  
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        Definition 
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         | 
        
        
        Term 
        
        | What are the requirements for successful transfer of passive immunity from cow to calve? |  
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        Definition 
        
        The calf consumes a sufficient amount of antibodies -depends on the [IgG] of the colostrum and the volume of colostrum
  Calf absorbs the colostral antibodies -depends on how long after birth the colostrum is consumed -cleanliness of colostrum also a factor |  
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        Term 
        
        | What effect does colostrum deprivation have on calf mortality? |  
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        Definition 
        
        | 74X greater risk of death in the  first 21 days of life! |  
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        Term 
        
        | What are some strategies for feeding colostrum? |  
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        Definition 
        
        4L in first feeding <6 hrs after birth
  4L at first feeding, 2L at 2nd feeding
  2 feedings of 2L in 4-8hr intervals |  
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        Term 
        
        | Why is relying on suckling not an effective means of passive transfer of antibodies? |  
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        Definition 
        
        -many calves do not manage to suckle within 6hrs -no way to know the volume of colostrum consumed -increased risk of ingestion of manure, hair etc. |  
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        Term 
        
        | How does an esophageal feeder work? What are the pros/cons? |  
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        Definition 
        
        Tube down esophagus directing colostrum to rumen -milk will move to abomasum within 2-4 hours
  Pros: very safe, easy to manage volume Cons: equipment must be cleaned well, possible reduction of absorption efficiency
  (absorption issues overcome by the volume fed & proper timing of feeding) |  
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        Term 
        
        True or False
  Colostrum replacers an supplements are equally as effective as colostrum produced by a cow |  
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        Definition 
        
        False
  They have reduced absorption efficiency (35-40%)
  -must be fed correctly and promptly for these to work |  
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        Term 
        
        | What are some potential sources of contamination of colostrum? Which is the most common? |  
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        Definition 
        
        -from teat -in bucket (most common cause of contamination) -coming out of tube feeder |  
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        Term 
        
        True or false
  With strict udder preparation, 100% of milk samples coming out of a cow are safe |  
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        Definition 
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        Term 
        
        | How long can colostrum be safely refrigerated? |  
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        Definition 
        
        1 day
  or up to 2 days if potassium sorbate is added |  
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        Term 
        
        | Describe the proper cleaning procedure for milking equipment? |  
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        Definition 
        
        1. Take apart all hoses, lids etc 2. Rinse with warm water (105F) 3. Soak in hot water (>120F) 4. Scrub all surfaces with >140F water & soap/chlorine detergent, use gloves! 5. Rinse with hot water & acid 6. Drain & air dry |  
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        Term 
        
        | What is ETEC? What does it do? |  
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        Definition 
        
        enteropathogenic E. coli
  -attach to pili of intestinal epithelial cells -gut absorbs the endotoxin, which causes excessive secretion of water & salts -results in diarrhea |  
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        Term 
        
        | When is ETEC most likely to affect a calf? What are the typical symptoms? |  
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        Definition 
        
        Less than 7 days old
  -profuse, watery, yellow diarrhea -severe depression -dehydration |  
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        Term 
        
        | At what age do rotavirus & coronavirus affect a calf? Which is more severe? |  
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        Definition 
        
        Rotavirus: 5-15 days Coronavirus: 5-21 days more severe |  
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        Term 
        
        | What effect to rotavirus & coronavirus have on a calf? |  
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        Definition 
        
        -tips of villi are destroyed -prevents digestion & absorption of milk -osmotic pressure causes increased water secretion into intestines, sometimes blood -diarrhea results |  
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        Term 
        
        | What is cryptosporidia? At what age is a calf most susceptible? |  
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        Definition 
        
        parasite which causes atrophy of villi, preventing digestion -not treatable -zoonotic
  affects most at 5-35 days of age |  
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        Term 
        
        | True or False Salmonellosis can affect mature cows as well as calves |  
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        Definition 
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        Term 
        
        | What is salmonellosis? What are the symptoms? |  
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        Definition 
        
        bacterial intestinal disease, causes wrinkled, rough intestinal epithelium
  -high fever, depression, blood & fibrin in stool |  
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        Term 
        
        | What are the 2 branches of treatment for diarrhea |  
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        Definition 
        
        Correct the fluid loss
  Antimicrobial treatment |  
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        Term 
        
        | What level of dehydration would result in mortality? |  
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        Definition 
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        Term 
        
        | What is the goal of treating dehydration? What are some appropriate methods? |  
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        Definition 
        
        -replace fluid deficit -replace electrolytes (Na, K, Cl, HCO3) -correct metabolic acidosis
  Mild/moderate dehydration: oral fluid therapy w/ esophageal tube & electrolyte solution
  Severe: IV fluid therapy |  
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        Term 
        
        | What are some of the drawbacks of antimicrobial treatment of diarrhea? |  
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        Definition 
        
        -difficult to clinically ascertain there is a microbial infection -bacteria can be resistant -not effective if the issue is viral / cryptosporidia -may inhibit 'good' bacteria |  
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         | 
        
        
        Term 
        
        | What methods of handling colostrum should be considered to improve prevention of diarrhea? |  
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        Definition 
        
        -4L fed in first 6-12H -goal of 6L total within 24H -cleanliness in harvest & feeding -colostrum from one dam to one calf -hand feed by bottle or esophageal feeder -freeze extra 1st milk colostrum |  
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        Term 
        
        | How can you improve the host specific immunity of colostrum? Why does this work? |  
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        Definition 
        
        -vaccinate pregnant cows with E.coli vaccine
  -improves the level of specific IgG in colostrum |  
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        Term 
        
        | What are the 3 means of preventing calf diarrea? |  
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        Definition 
        
        Improve immunity of calf via quantity & quality of colostrum Improve specific immunity of colostrum Improve nutrition (no soy protein source) |  
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        Term 
        
        | What is the thermoneutral zone for calves <21 days of age? >21 days? |  
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        Definition 
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         | 
        
        
        Term 
        
        | What is the traditional approach of feeding dairy calves? What is the issue? |  
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        Definition 
        
        10% of birth weight (2L) 2X a day, goal is to get calf on solid food by 4-5 weeks
  -this volume is below maintenance level for a 50kg calf at 0C , need at least 5L |  
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        Term 
        
        | How much milk with a calf drink if given free choice? What are the benefits of this? Cons? |  
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        Definition 
        
        8-12 L per day
  Pros: -accelerated growth rate -produce up to 500kg more milk in first lactation
  Cons: -more expensive -milk may spoil (can prevent this with acidification!) |  
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         | 
        
        
        Term 
        
        | Describe an example of a milk feeding program for holstein calves |  
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        Definition 
        
        -6L colostrum in first 24h
  -milk/replacer 2+ feedings per day or ad libidum
  6L/day in week 1 8-10L/day in week 2-7 4L/day in week 8
  Wean at week 8
  *offer water & starter grain free-choice throughout this process |  
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         | 
        
        
        Term 
        
        True or False
  Pasteurization and sterilization are the same thing |  
          | 
        
        
        Definition 
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         | 
        
        
        Term 
        
        | Why would you pasteurize milk? |  
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        Definition 
        
        | To treat waste milk to it can be fed at a different time |  
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         | 
        
        
        Term 
        
        | What management practices can reduce the risk of exposing a calf to pathogens? |  
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        Definition 
        
        -calve in a clean environment -use clean equipment -remove calf from cow immediately after birth -keep calf in a hutch or individual pen until weaning -use isolation facilities for sick calves -use group pens after weaning? |  
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         | 
        
        
        Term 
        
        True or False
  Enzootic pneumonia can be caused by both bacteria and viruses |  
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        Definition 
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         | 
        
        
        Term 
        
        | What are some symptoms of enzootic pneumonia? |  
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        Definition 
        
        -upper respiratory bronchopneumonia -mild to high fever -coughing & nasal discharge -sometimes reduced growth rate |  
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         | 
        
        
        Term 
        
        | What might cause enzootic pneumonia? |  
          | 
        
        
        Definition 
        
        poorly ventilated enclosure -high humidity, ammonia, exposure to other cattle
  inadequate IgG levels overcrowding temperature fluctuations poor nutrition drafts |  
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         | 
        
        
        Term 
        
        | What vessels are found within the umbilicus>? |  
          | 
        
        
        Definition 
        
        2 hepatic arteries & 1 hepatic vein
  urachus to bladder |  
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         | 
        
        
        Term 
        
        | What is omphalophlebitis> |  
          | 
        
        
        Definition 
        
        infection due to poor passive transfer & poor calving hygiene
  -local infection in cord, forming abscesses eventually in abdomen up to the liver
  -infection can spread to other areas such as joints |  
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         | 
        
        
        Term 
        
        | If a young calf has a joint infection, what is the most likely cause? |  
          | 
        
        
        Definition 
        
        | spreading of bacteria from the umbilicus (omphalophlebitis) |  
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         | 
        
        
        Term 
        
        | How can you prevent omphalophlebitis? |  
          | 
        
        
        Definition 
        
        -clean & dry calving area -disinfect navel with 7% iodine |  
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         | 
        
        
        Term 
        
        | What is an umbilical hernia? What is the typical treatment? |  
          | 
        
        
        Definition 
        
        -defect in ventral abdominal wall around the umbilicus
  -tape it if small, surgery if large or not treated early enough |  
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         | 
        
        
        Term 
        
        | What is the purpose of ear tagging? |  
          | 
        
        
        Definition 
        
        -herd management -ownership -traceability -national disease surveillance & outbreak investigation |  
          | 
        
        
         | 
        
        
        Term 
        
        | What are some recommendations for proper dehorning practices? |  
          | 
        
        
        Definition 
        
        -dehorn as young as possible -use local anesthetic -use anti-inflam drugs if dehorning >4wks of age |  
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