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Definition
Only gaseous form of anesthetic used, others are volatile liquids
.47 blood/gas partition therefore very fast induction
LOW lipophilicity, therefore the partial pressure of NO rises quickly in the plasma
High arterial gas tension
MAC is 101 (101% of atmospheric pressure, obviously not possible so “incomplete”)
Can use with other GAs to reduce side effect of increased PaC02, decreased TPR (NO will actually increase TPR slightly) |
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Definition
13 blood/gas partition coefficient (very soluble in blood) therefore very slow induction..does not mean it is “hydrophilic” actually VERY lipophilic and binds to blood proteins as an INACTIVE reservoir
About 50% of absorbed dose is metabolized because of high solubility
Not used anymore |
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Term
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Definition
Intermediate induction, intermediate arterial gas tension
Decreased TPR as you increase dose
Drug of choice with high intracranial pressure patients
Less soluble so only 0.17% metabolized, relatively safe! |
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Definition
.45 blood/gas partition therefore very fast induction, high arterial gas tension
Decreased TPR as you increase dose
Less soluble so only 0.02% metabolized, relatively safe! |
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Definition
.65 blood/gas partition therefore very fast induction, high arterial gas tension
Decreased TPR as you increase dose, also decreases CO
Less soluble so only 3% metabolized, significant amounts can cause fluoride buildup so use for short outpatient procedures only |
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Term
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Definition
Ultra-short acting barbiturate
Used for induction of anesthesia (helps pass excitatory phase quickly)
Rapid diffusion, rapid redistribution so not for long term use |
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Definition
Chemically unrelated to other IV anesthetics (oil at room temperature)
Emergence from anesthesia with propofol is more rapid than thiopental
Minimal postoperative confusion
Great drug for inducing anesthesia, smaller doses for sedation during intensive care |
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Definition
| Increase GABA transmission, by increasing the number of available GABA receptors, used for induction, codes. Very short acting, minimal depression of respiration and CV system, use in codes when you need to intubate |
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Definition
| Anticholinergic to minimize secretions from GA irritation of bronchial tubes |
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Definition
| Stabilize the sarcoplasmic reticulum without interfering with action potentials, used for malignant hyperthermia with anesthesia (genetic predisposition side effect of GAs) |
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