Term
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Definition
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Term
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Definition
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Term
| Three main plasma proteins: |
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Definition
Albumins
Globulins
Fibrinogen |
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Term
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Definition
| Increases osmotic pressure in blood |
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Term
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Definition
Transportation of certain substances
Helps protect against infection
Main component of antibodies |
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Term
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Definition
| Important for blood clotting |
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Term
| Cellular components of blood |
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Definition
| RBCs, WBCs, and platelets |
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Term
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Definition
Ability to change shape
120 day life span
Undergo recycling process |
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Term
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Definition
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Term
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Definition
| Each Hgb molecule can carry 4 Fe- molecules |
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Term
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Definition
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Term
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Definition
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Term
| Trigger for RBC production |
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Definition
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Term
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Definition
RBC growth factor
**At rate of RBC destruction |
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Term
| Excessive tissue oxygenation result |
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Definition
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Term
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Definition
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Term
| Essential substances to form RBC/Hgb |
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Definition
| Fe-, B12, Folic Acid, Pyridoxine |
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Term
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Definition
Located under diaphragm to left of stomach
Stores RBCs and platelets
Destroys old or imperfect RBCs
Filters antigens |
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Term
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Definition
Can store large quantities of whole blood & cells
Produces most of blood clotting factors
Stores extra Fe- as ferritin
Small amounts of EPO produced in liver
Controls Vitamin K |
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Term
| Age-related changes re: blood |
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Definition
Decreased blood volume
Decreased blood cell production
Decreased levels of Hgb after middle age |
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Term
| Dx tests r/t blood issues |
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Definition
CBC [RBCs, WBC w/ differential, MCV, MCHC, MCH, H&H, platelets]
Retic count
Serum ferritin
Transferrin
TIBC
Schilling test |
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Term
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Definition
Male: 14-18; 42-52%
Female: 12-16; 37-46% |
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Term
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Definition
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Term
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Definition
| measures free Fe- in blood |
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Term
| Serum Ferritin: nsg consideration |
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Definition
| Must know baseline to determine abnormality |
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Term
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Definition
Protein which transports Fe- from GI tract
**Difficult to measure |
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Term
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Definition
Total iron binding capacity
*Measures how much Fe- is bound to ferritin |
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Term
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Definition
Tests for pernicious anemia
Evaluates vitamin B12 absorption |
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Term
| Schilling test: nsg considerations |
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Definition
| Ct must save all urine for 24-48 hours |
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Term
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Definition
Radioactive B12 given orally
Nonradioactive B12 given IM
**IM absorbs faster |
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Term
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Definition
| Reduction in either # of RBCs, amount of Hgb or Hct |
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Term
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Definition
| Dietary issues, hemorrhage, organ/marrow failure, Drug ingestion, genetic aberrations, surgical procedures, rapid metabolic activity, malabsorption syndromes, dialysis, viral infection |
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Term
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Definition
Fe- is essential for life
2/3 of Fe- is contained in Hgb
1/3 stored in bone marrow, liver, muscle & spleen
*Stores are used before Hgb in deficiency |
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Term
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Definition
| Most common form of anemia |
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Term
| Iron deficiency: inadequate iron intake r/t |
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Definition
Fe deficient diet
Chronic ETOH use
Malabsorption syndromes
Partial gastrectomy |
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Term
| Pts at high risk for iron def. |
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Definition
Women
elderly
adolescents
those with poor nutrition |
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Term
| Iron Deficiency: Clinical Manifestations |
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Definition
Small RBCs (microcytic)
Decreased MCV
Low serum ferritin
Weakness
Pallor |
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Term
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Definition
Increase intake of Fe-rich foods
Take oral Fe supplement |
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Term
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Definition
| Organ meats, kidney beans, red meat, egg yolks, carrots, green veg, whole wheat, cereals, and raisins |
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