Term
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Definition
variation in size of RBC
-measured by RDW |
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Term
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Definition
| variation in shape of RBC |
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Term
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Definition
| RBC distribution width-measure of the variation in size of RBCS |
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Term
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Definition
| nuetrophil with a dense, hyposegmented nucleus and hypogranular |
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Term
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Definition
| -iron difeicience, thalessemia, anemia of chronic disease, lead poisening |
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Term
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Definition
| neonate, liver diease and endocrine disorders, vitamine b12/folate, myelodysplastic syndrome |
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Term
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Definition
| iron deficiency, thalassemia, lead posoining (all microcytic) and siderblastic anemia |
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Term
|
Definition
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Term
|
Definition
burr or crenated cell-star shaped
-unevely spaced projections, artifact, uremia, and pyruvate kinase dificiency |
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Term
|
Definition
spur cell, worse than echinocyte, star shaped
-irregular projections, altered lipid content in membrane
-abetalipoprotienemia (no ApoB-malabsorption of fat and ADEK), severe liver disease, unusual blood group (McLeod phenotype), spelectomy, malabsorption, hypothyroidism, Vit. E dificiency |
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Term
| Kerateocyte (helmet/bite cell) |
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Definition
| -thrombotic thrombocytopenic purpura (TTP), disseminated intravascular coagulation (DIC), Hemolytic uremic syndrome (HUS), Microangiopathic autoimmune hemolytic anemia (MAHA) |
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Term
|
Definition
transfused cells, severe burnes, hereditary spherocytosis
- |
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Term
|
Definition
target cell
-artifact, loss of Hb or cell volume, in surface membrane
-hemoglobinopathies, thalassemia, iron deficiency, splenectomy, liver disease |
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Term
|
Definition
tear drop cell
-abnormal microvasculature of marrow or spleen
-marrow infiltration (myelofibrosis, myelophtisic anemia), extramedullary hematopoiesis, thalassemia, pernicious anemia |
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Term
|
Definition
| heriditary elliptocytosis, thalassemia major, iron deficiency anemia |
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Term
|
Definition
| red cell fragmentation, MAHA, DIC, HUS, TTP, mechanical valve, burns |
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Term
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Definition
| red cell fragmentation, MAHA, DIC, HUS, TTP, mechanical valve, burns |
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Term
|
Definition
"lips" slit of pallor center
-herditary stomatocytosis, alcoholism, liver disease, Rh null phenotype, artifact |
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Term
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Definition
-Dark-blue purple nuclear remnants containing DNA
-accelerated or abnormal erythropoiesis
-usually one, can be multiple
-splenectomy, megaloblastic anemia, hemolytic anemia
-signs of stress in BM- reticulocytes, howell-jolly bodies, nucleated RBCs |
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Term
|
Definition
siderotic granules-light blue composed of non heme iron
-splenectomy, hemolytic, megoblastic anemia, hemoglobinopathy, sideroblastic anemia |
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Term
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Definition
-different colors-from reticulocytes or precipitated RNA (stain with methylene blue)
-acute/chromic hemorrhage, hemolysis, effective treatment of anemia, neonates |
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Term
|
Definition
-small, rounded inclusions of Hb
-single or multiple, negative for iron
-G6PD and hemoglobinopathy |
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Term
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Definition
-evenly distributed dark blue/purple granules composed of RNA
-LEAD, thalassemia, abnormal heme synthesis, siderblastic anemia
- |
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Term
|
Definition
dark blue/purple ring or figure 8
-remnant of mitotic spindle
-megaloblastic anemia and MDS |
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Term
|
Definition
-stacks of coins
-monoclonal gammopathies, increase polyclonal gammerglobulins, liver disease, hyperfibrinogenemia |
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Term
|
Definition
-increase IgM
-mycoplasma, infection mono (and other viral infections, neoplasms (**lymploplasmacytic lymphoma (LPL)) |
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Term
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Definition
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Term
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Definition
| -stem cell marker. Also on mast cells and endothelial cell (less specific) |
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Term
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Definition
| benign lymphoid precursor in BM, small to itnermediate sized lymphocyte |
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