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Anatomy and Physiology
The Heart
61
Biology
Undergraduate 2
12/06/2009

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Term
Circulatory System
Definition
heart, blood vessels and blood
Term
Cardiovascular System
Definition
Heart, arteries, vein and capillaries
Term
Pulmonary Circuit
Definition
Right side of heart: carries blood to lungs for gas exchange
Term
Systemic Circuit
Definition
Left side of heart: Supplies blood to all organs of the body
Term
What occurs when ventricles relax?
Definition
1. pressure drops
2. Semilunar valves close
3. AV valves open
4. Blood flows from atria to ventricles
Term
What occurs when ventricles contract?
Definition
1. AV valves close
2. pressure rises
3. Semilunar valves open
4. Blood flows into great vessels
Term
Which vessel supplies 2/3 of blood supply to heart?
Definition
Left coronary artery
Term
Which vessel supplies 1/3 of blood supply to heart?
Definition
Right coronary artery
Term
Angina Pectoris
Definition
Partial obstruction of coronary blood flow, causes pain in chest
Term
Myocardial Infarction
Definition
Heart attack, caused by death of myocardial cells, due to lack of oxygen
Term
Which vessels drain into the coronary sinus?
Definition
great cardiac vein, middle cardiac vein and left marginal vein
Term
Describe sympathetic nerve supply to heart
Definition
Upper thoracic spinal cord, to sympathetic chain, to cardiac nerves.
Term
sympathetic heart rate
Definition
up to 230 bpm
Term
parasympathetic nerves
Definition
right vagal to SA node
Left vagal to AV node
Term
parasympathetic heart beat
Definition
70-80 bpm
Term
Define SA node
Definition
initiates heartbeat, sets heart rate
Term
Fibrous Skeleton function
Definition
insulates atria from ventricles
Term
Define AV node
Definition
electrical gateway to ventricles
Term
Define AV bundle
Definition
pathway for signals from AV node to bundle branches
Term
Define L/R bundle branches
Definition
divisions of AV bundle into interventricular septum
Term
Define Perkinje fibers
Definition
travel from apex through ventricular myocardium
Term
electrical junctions
Definition
gap junction in cardiac muscle that allow ions to flow
Term
systole
Definition
ventricular contraction
Term
diastole
Definition
ventricular relaxation
Term
Where does ventricular systole begin?
Definition
Apex
Term
SA action potential threshold
Definition
-40mV
Term
Which channels open during SA node depolarization?
Definition
fast Ca2+
Term
Which channels open during SA node repolarization?
Definition
K+
Term
When do K+ channels close in SA node?
Definition
-60mV
Term
What is the resting potential of SA node?
Definition
It does not have one
Term
What is the resting potential of myocytes?
Definition
-90mV
Term
List 5 steps of a myocyte action potential
Definition
1. Na+ gates open
2. rapid depolarization
3. Na+ gates close
4. Slow Ca2+ channels open
5. Ca2+ channels close, K+ channels open
Term
P wave (ECG)
Definition
1. SA node fires
2. atrial depolarization and systole
Term
QRS complex (ECG)
Definition
1. ventricular depolarization
2. atrial repolarization and diastole
Term
ST segment (ECG)
Definition
ventricular systole
Term
T wave (ECG)
Definition
ventricular repolarization
Term
Define Cardiac Cycle
Definition
one full contraction (systole) and relaxation (diastole) of the heart
Term
Ectopic foci
Definition
region of spontaneous firing (not SA node)
Term
arrhythmia
Definition
abnormal cardiac rhythm
Term
What is a premature ventricular contraction caused by?
Definition
hypoxia, electrolyte imbalance, stimulants, stress
Term
Define auscultation
Definition
listening to sounds made by body
Term
What happens during the Quiescent Period?
Definition
1. All chambers are relaxed
2. AV valves open
3. Blood flows into ventricles
Term
Steps of Atrial Systoles
Definition
1. SA node fires (atria depolarize)
2. P wave on ECG
3. Atria contract, force blood into ventricles
4. ventricles contain EDV
Term
Isovolumetric Contraction of Ventricles
Definition
1. Atria repolarize and relax
2. Ventricles depolarize
3. QRS complex on ECG
4. Ventricles contract
5, AV valves close (S1)
Term
Steps of Ventricular Ejection
Definition
1. Semilunar valves open
2. Rapid ejection of blood, then reduced
3. Stroke Volume (70mL at rest)
4. SV/EDV= ejection fraction
5. EDV-amount left in heart after ejection
Term
What are the ejection fractions:
-normal
-vigorous exercise
-diseased heart
Definition
-54%
-90%
less than 50%
Term
Isovolumetric relaxation of ventricles
Definition
1. T wave on ECG
2. Ventricles repolarize and relax
3. Semilunar valves close (S2) AV stay closed
4. Ventricles expand, do not fill
Term
3 phases of ventricular filling
Definition
1. Rapid ventricular filling (AV valves first open)
2. Diastasis (low pressure, venous return)
3. Atrial systole (filling completed)
Term
Define EDV
Definition
End Diastolic Volume: Amount of blood in ventricles after ventricular diastole
Term
Define ESV
Definition
Amount of blood in ventricles at the end of ventricular Systole
Term
Define ESV
Definition
Amount of blood in ventricles at the end of ventricular Systole
Term
Define Stroke Volume
Definition
The amount of blood pumped out of each ventricle during a single beat (SV= EDV-ESV)
Term
Define Cardiac Output
Definition
Amount of blood ejected by ventricle in 1 minute (CO=HRxSV)
Term
Define cardiac reserve
Definition
difference between a person's maximum and resting cardiac output
Term
Tachycardia: definition and causes
Definition
HR about 100, stress, anxiety, drugs, heart disease, increase body temp.
Term
Bradycardia: Definition and causes
Definition
HR below 60, sleep and endurance trained athletes
Term
Cardiac Center of Medulla Oblongata
Definition
autonomic control center with cardioacceleratory(sympathetic) and cardioinhibitory (para) neuronal pools
Term
What does the cardioacceleratory center stimulate?
Definition
SA node, AV node and myocardium
Term
What hormone do Sympathetic nerves release to heart? What does it bind to?
Definition
norepinephrine, which binds to beta-adrenergic receptors in heart.
Term
What does the cardioinhibitory center stimulate? Which hormone is secreted?
Definition
Right and Left vagus nerves
right-SA node
left-AV node
ACH, which binds to muscarinic receptors
Term
What kind of imputs are there to the cardiac center?
Definition
1.higher brain centers )cerebral cortex, limbic system and hypothalamus)
2. proprioceptors
3. baroreceptors
4. chemoreceptors
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