Term
|
Definition
| the largest gland in the body weighing at 3 lbs, it has serosa extept at the bare area. The diaphragm and the liver are connected. |
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Term
| The liver has both exocrine and endocrine properties. It's functions include: |
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Definition
1. Making bile
2. Making blood proteins (Albumin)
3. Store Excess glucose as glycogen
4. Store fat soluble vitamins like A
5. Primary organ of drug metabolism |
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Term
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Definition
| is right next to the gallbladder |
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Term
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Definition
| is the entry way to the liver, containing the hepatic artery (carrying O2 rich blood to the liver), the Hepatic portal vein (carrying things absorbed from intestines), and the left hepatic duct which transports bile. |
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Term
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Definition
| the smallest section of the liver, at its 6 corners it has portal triads and portal tracts. Has a central vein at its center, with hepatocytes branching off. |
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Term
| The portal triad contains... |
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Definition
| a branch of the bile duct, a branch of the hepatic portal vein, and a branch of the hepatic artery. |
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Term
| The parenchymal cell is the... |
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Definition
| main cell of the liver, making up 80% of it |
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Term
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Definition
| large leaky capillaries between the hepatocytes, lined by discontinuous endothelium. They have a mixing of arterial and vein blood. |
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Term
| What are the organelle concentrations in hepatocytes and what is their function? |
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Definition
| High SER to make (Exocrine), High RER and Golgi to make albumin (endocrine), High SER and Peroxisomes and abundant mitochondria to aid in fat storage and drug metabolism. |
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Term
| Describe the flow of nutrients in the hepatocytes |
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Definition
| Bile enters the bile canalculus, blood protein and glucose enters the sunisoid, and nutrients and toxins enter the hepatic cell. |
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Term
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Definition
| the macrophage of the Liver |
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Term
| The Stroma of the liver... |
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Definition
| is the supporting tissue that is reticular CT. |
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Term
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Definition
| stores and concentrates bile |
|
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Term
| Can you live without a gallbladder? |
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Definition
|
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Term
|
Definition
| muscles around the gallbladder contract, extreting it's extra bile into duodenum |
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Term
| What 3 things dump into the duodenum? |
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Definition
| Chyme, Bile, and Pancreatic enzymes |
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Term
| The Acinar cells in the pancreas are |
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Definition
|
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Term
| Inactive form of enzymes in the pancreas are stored in... |
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Definition
|
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Term
| Saliva is composed of _________________________________ and it functions to ______________ |
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Definition
H2O, ions, mucus, ENZ, and bicarbonate;
Moistens mouth, binds food, making bolus |
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Term
| The enzyme in saliva ____________ and bicarbonate ________________ |
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Definition
starts starch digestion;
Neutralizes acid from bacteria |
|
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Term
| What are the types of glands in the mouth |
|
Definition
Parotid - Purely Serous
Submandibular - Mucus and Serous
Sublingual - Mucus and Serous |
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Term
|
Definition
Serous secretion - watery, ions, ENZ
Mucous secretion - thick mucus |
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Term
| Glands in the tongue are.... |
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Definition
|
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Term
| What are the basic organs of the respiratory system? |
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Definition
| Nose, oral cavity, Larynx, the Bronchii, the pharynx, the trachea, and the lungs |
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Term
|
Definition
|
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Term
| Right lung has _ lobes, and left lung has _ lobes |
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Definition
|
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Term
|
Definition
1. Passage way for air
2. Contitions air (warm, moisten, clean)
3. Involved in phonation |
|
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Term
| Conducting vs respiratory zones |
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Definition
Conducting zone- No gas exchange, a passage way that conditions air by cleaning, moistening and warming it. anything not listed below.
Respiratory zone - Gas exchange is possible, alveoli are present. Respiratory bronchiole, alveolar duct, alveolar sac, and alveoli. |
|
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Term
| the Nasal Vestibule is... |
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Definition
| the part of the inside of the nose that has hair and sweat glands |
|
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Term
| Describe the nasal cavities properties |
|
Definition
1. Has olfactory mucosa - limited to superior concha housing olfactory epithelium
2. Respiratory mucosa - epithelium and lamina propria, pseudostratified ciliated columnar epithelium and goblet cell. |
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Term
| The lamina propria in the respiratory tract... |
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Definition
| contains seromucous glands that moisten the air, alot of capillaries and veins used to warm the air |
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Term
|
Definition
|
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Term
| The parts of the pharynx are... |
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Definition
| Nasopharynx (respiratory mucosa), the oropharynx (stratified squamous), and the laryngopharynx (stratified squamous) |
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Term
| Soft pallette serves to... |
|
Definition
| prevent food from entering the nasal area |
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Term
| Describe the 2 folds in the trachea |
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Definition
| the vestibular fold, and the vocal fold which holds vocal ligaments |
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Term
| The larynx has _ named cartilages |
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Definition
|
|
Term
| The 3 functions of the larynx: |
|
Definition
1. Voice production
2. Passage way
3. Switching mechanism between air and food |
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Term
|
Definition
1. Epiglottis
2. Cuniform cartilages
3. Corniculate cartilages
4. Arytenoid cartilages (start of vocal cords)
5. Cricoid cartilages
6. Tracheal cartilages
7. thyroid cartilage (end of vocal cords) |
|
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Term
|
Definition
| the opening between the true vocal cords |
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Term
|
Definition
has 16-20 c shaped hyaline cartilage rings with fibroelastic CT between C cartilage. It has 4 layers
1.Mucous membrane
2. Submucosa
3. Hyaline cartilage
4. Advantitia |
|
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Term
|
Definition
| controls diameter of the lumen of the trachea and connects between the hyaline cartilages |
|
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Term
|
Definition
Mams=primary bronchi, 1/lung
Lobar=secondary bronchi 1/lobe
Segmental=tertiary bronchi 1/segment
bronchiole<1mm, no cartilage
Terminal bronchiole<0.5mm |
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Term
| Changes from in bronchial tree: |
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Definition
| Decrease in cartilage, decrease in height of epithelium (pseudostratified columnar, simple columnar to cuboidal), increase in elastic fibers, increase in smooth muscle |
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Term
|
Definition
| respiratory bronchioles, alveolar duct, and alveolar sac |
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Term
| ________ branch off the sides of the alveolar duct, and at the end there are __________ |
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Definition
|
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Term
| A type 1 pneumocyte is... |
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Definition
|
|
Term
| On the outside of all the alveoli are... |
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Definition
| capilaries and elastic fibers |
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Term
| The type 1 pneumocyte, the fused basal lamina and the endothelium of the capilary comprise the _______________ |
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Definition
| Blood-air barrier AKA the repsiratory membrane |
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Term
| The type II pneumocyte performs what functions? |
|
Definition
1. Stem Cell
2. Produces surfactant (reduces surface tension, coats inner surface of the alveolus) |
|
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Term
|
Definition
| a macrophage that cleans the alveolus, also known as PAM (pulmonary alveolar macrophage) |
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Term
|
Definition
| allows for equilibrium of air, and allows for alternate routes for air to flow |
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Term
| Lymphatic vessels - think... |
|
Definition
Transport lymph
and return lymph to veins in base of neck |
|
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Term
|
Definition
| provides immunity, long term resistance |
|
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Term
|
Definition
| Lymph duct, lymph trunk, lymph node, lymphatic collecting vessels with valves, lymphatic capillaries |
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Term
| Lymph is a _ way flowing system |
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Definition
|
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Term
| Tissue fluid contains ______________, and what moves into the lymphatic capillaries is called ______ |
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Definition
| H2O, blood proteins, cells, pathogens, bacteria, cancer cells, etc.; Lymph |
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Term
|
Definition
| remove the components of tissue fluid that aren't wanted |
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Term
|
Definition
|
|
Term
| How does tissue fluid enter the capillaries? |
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Definition
| The endothelium has callogen fibers which connect to the local tissue, when it swells, it causes the valve to open, allowing tissue fluid in, until swelling goes down when it closes. |
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Term
| Collecting vessels, lymph trunk, and lymph duct are structured like... |
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Definition
| Blood vessels, in that they have the same 3 layers |
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Term
| Tunica intima is composed of... |
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Definition
|
|
Term
| Tunica media is composed of- |
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Definition
|
|
Term
| lymphnodes are located... |
|
Definition
| in the path of collecting vessels |
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Term
|
Definition
|
|
Term
| The intestinal trunk and the lumbar trunk form... |
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Definition
|
|
Term
| the thoracic duct returns lymph from... |
|
Definition
|
|
Term
| The beginning of the thoracic duct is the... |
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Definition
|
|
Term
| Thoracic duct dumps its lymph betwen |
|
Definition
| the subclavian vein and the jugular vein |
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Term
|
Definition
Parenchymal cell= lymphocyte
Stroma= reticular CT (except in thymus)
Cells= B lymphocyte and T lymphocyte, plasma cells, macrophages
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|
|
Term
B. lymphocyte vs T lymphocyte
(when exposed to antigen) |
|
Definition
B lymphocyte converts to a plasma cell, which produces antibodies to attach antigens. Memory cells (lymphocytes on reserve) ready to respond to 2nd exposure. Humoral immunity.
T lymphocytes has memory cells as well. I has helper cells, and cytotoxic cells. They respond to antigens on cell membranes, respond to eukaryotic cells (cancer, virally infected, fungal, transplanted cells). Cell mediated immunity. |
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Term
|
Definition
| antigen presenting cells, and phagocytosis |
|
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Term
|
Definition
| highly concentrated area of lymphocytes, just B cells |
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Term
|
Definition
| Indicates an immune response, |
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Term
|
Definition
| MALT (mucosa associated lymphoid tissue) |
|
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Term
|
Definition
| Leukocytes, agranulocytes |
|
|
Term
| All lymphocytes originate from... |
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Definition
|
|
Term
|
Definition
| thymus to become immunocompetent. They have the ability to recognize foreign material. |
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Term
| B cells do what to become immunocompetent? |
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Definition
|
|
Term
| The organs in the lympoid system are.. |
|
Definition
| the tonsils, the thymus, the spleen, the aggregated lymphoid nodules and the appendix |
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Term
|
Definition
| has cortex & medula, B+T cells, stroma is reticular CT, functions to remove pathogens, cancer cells.... from lymph. ~500 exist |
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Term
|
Definition
| Has a cortex and medulla, No B cells only T cells, Stroma is epithelial reticular cells, only lymphoid organ that does not mount an immune response, has a blood-thymus barrier. It functions as the site where T cells become immunocompetent. |
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Term
|
Definition
No cortex & medulla but has red pulp and white pulp, has B & T cells, stroma is reticular CT.
Red pulp removes damaged or dead RBC's.
White pulp removes blood-borne pathogens, and has the immune function |
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Term
|
Definition
| No cortex & medulla, contains B & T cells, Stroma is reticular CT, located in the mucosa of pharynx. Only lymphoid organ that is covered by an epithelium. |
|
|
Term
| What can you survive without? |
|
Definition
A few lymphs (concentrated removal is bad)
thymus can be removed but life is tricky since there are no T cells
Spleen can be removed
Tonsils can be removed |
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Term
|
Definition
| a channel for lymph, lined by endothelium |
|
|
Term
| Lymphnode trabeculae are... |
|
Definition
|
|
Term
|
Definition
| B & T cells (extension of cortex), macrophages and plasma cells |
|
|
Term
| Afferent vs efferent lymphatic vessels |
|
Definition
| Flow goes from afferent to efferent vessels |
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Term
|
Definition
| a point where structures enter or exit or both |
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|
Term
| What is the only WBC that can re-circulate? |
|
Definition
|
|
Term
| As you get older the thymus goes through the process of __________ which is when... |
|
Definition
| involution: thymic tissue is mostly replaced by adipose |
|
|
Term
| The function of the lymphnode is... |
|
Definition
| to remove pathogens from the lymph |
|
|
Term
| Medulary cords are cellular, containing... |
|
Definition
| B&T cells, macrophages and plasma cells |
|
|
Term
| Degenerative epithelial-reticular cells are found in the _________ of the thymus and are called _________ |
|
Definition
| medulla; Thymic (Hassall's) corpuscles |
|
|
Term
| The hormones in the thymus... |
|
Definition
| allow the T cells to become immunocompetent |
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|
Term
| White pulp in the spleen... |
|
Definition
| is made of PALS and of lymphoid tissue |
|
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Term
|
Definition
| Pariarterial lymphatic sheath, which are the sleeve of T cells/B cells |
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|
Term
| The spleen has a _______ capsule, because it is... |
|
Definition
| thick; very bloody, and rupturing could cause one to bleed out |
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Term
|
Definition
|
|
Term
| Once the splenic artery leaves the connective tissue and enters the matter of the spleen, it is called... |
|
Definition
|
|
Term
| The central artery may not appear to be _________ because of B cell __________ |
|
Definition
|
|
Term
|
Definition
|
|
Term
| The venous sinuses of red pulp contain ____ |
|
Definition
|
|
Term
| Cords in Red pulp mainly contain... |
|
Definition
|
|
Term
|
Definition
| in the mucosa of the pharynx |
|
|
Term
| the 2 sets of tonsils are... |
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Definition
| the pharyngeal (pseudostratified ciliated epithelium) and the palatine (stratified squamous non-keratinized) |
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|
Term
| Which kidney is more superior than the other? Why? |
|
Definition
| the left kidney due to the liver blocking the other kidney |
|
|
Term
| What 4 things surround/protect the kidneys? |
|
Definition
1. fibrous capsule
2. Perirenal fat capsule
3. The anterior and posterior renal fascia
4. Pararenal fat |
|
|
Term
| What is the function of the kidney? |
|
Definition
It filters blood conserving H2O, ions, A.A's, and glucose, while it secretes wastes (urea, uricacid) drug metabolites, ions, H2O
It forms concentrated urine |
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|
Term
| What is unusual about the kidney's medula? |
|
Definition
| it is in the shape of pyramids |
|
|
Term
| The region where the renal cotrex is between the medullar pyramids is called... |
|
Definition
|
|
Term
| Kidneys have ______ lobes, which consist of.... |
|
Definition
| 7-11; medullary pyramid and associated cortical tissue |
|
|
Term
| What is the path of blood through the kidney? |
|
Definition
| Renal artery to segmental artery to lobar artery to interlobar artery, to arcuate artery to interlobular artery |
|
|
Term
| What is the functional unit of the kidney? How many are there? What does it consist of? |
|
Definition
| the nephron; 1million; Renal corpuscle and tubular portion |
|
|
Term
| The renal corpuscle is the site of... |
|
Definition
|
|
Term
| the tubular portion is the site of... |
|
Definition
| reabsorption and secretion |
|
|
Term
| The uriniferous tubule consists of... |
|
Definition
| the nephron and the collecting ducts |
|
|
Term
| Renal corpuscle consists of... |
|
Definition
| the glomerulus and the bowman's capsule |
|
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Term
|
Definition
| a tuft of capillariers, fenestrated |
|
|
Term
| the bowman's capsule is composed of... |
|
Definition
| simple squamous epithelium comprising the parietal layer (outside) and the visceral layer (hugs the glomerulus) |
|
|
Term
| The capsular space (AKA urinary space)... |
|
Definition
| is the space between the visceral and parietal layers of the bowman's capsule |
|
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Term
|
Definition
| small pores in capillaries that are small enough to not allow cells through but fluids |
|
|
Term
| The layers of the podocyte are... |
|
Definition
1. The fenestrated capillary endothelium
2. The basement membrane
3. The filtration slits |
|
|
Term
| The molecular barrier functions to... |
|
Definition
| blocks material due to charge and or size |
|
|
Term
| After the bowman's capsule comes the... |
|
Definition
| proximal convoluted tubule P.C.T. |
|
|
Term
| proximal convoluted tubule P.C.T. is composed of_____________________ and it's function is... |
|
Definition
simple cuboidal epithelium, microvilli, and mitochondria;
reabsoprtion and secretion |
|
|
Term
| What are the parts and functions of the loop of henle? |
|
Definition
Thick descending limb, functions like the PCT
The thin limb, functions to concentrate the urine
Thick ascending limb, functions like the DCT |
|
|
Term
| describe the distal convoluted tubule (aka DCT) |
|
Definition
| shorter than the PCT, it's simple cuboidal epithelium and has selective ion secretion (Potassium), and selective ion reabsorption (NCl), it has fewer microvilli and mitochondria than the PCT |
|
|
Term
| The collecting duct serves as... |
|
Definition
| the kidney's last chance to reabsorb water |
|
|
Term
| ADH and aldosterone serve to... |
|
Definition
| Anti diuretic hormone effects the collecting duct, and aldosterone (from the zona glomerulosa of the renal cortex) causes an increase of Na+ reabsorbtion in the DCT |
|
|
Term
| Cortical nephrons vs juxtamedullary nephrons |
|
Definition
Cortical- 85% of nephrons, almost entirely located in the cortex, the thin segment of the loop of henle is extremely small
Juxtamedullary- 15% of nephrons, they have the longest thin limbs of henle that concentrate the urine |
|
|
Term
| from the efferent arteriol arises |
|
Definition
| the eritubular capillaries |
|
|
Term
| materials reabsorbed via tubules are colected in __________. Waste materials to be secreted by the kidneys are delivered via _____________ |
|
Definition
|
|
Term
| The capillaries associated with the justamedullary nephron are... |
|
Definition
| the vasa recta, they arise from the efferent arteriol |
|
|
Term
| The juxtaglomerular apparatus functions to ________ and is composed of... |
|
Definition
| regulate BP; the macula densa and the granular cells (AKA JG cells) |
|
|
Term
| describe JG cells (granular) |
|
Definition
| The are modified sm. muscle cells of the afferent arteriole, they contain granules with renin and detect change in blood volume. Decrease in blood volume causes them to release renin, to increase the release of aldosterone, and causes an increase in Na+ absorption and H2O absorbtion. Increasing blood volume and BP. |
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|
Term
| Describe the macula densa |
|
Definition
| modified regtion of DCT, they detect the concentration of Na+ in the blood. If there is a decrease in Na+, they tell the JG cells to release renin |
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|
Term
| Describe the path of Urine. What epithelium lines each? |
|
Definition
1. Minor Calyx (1/lobe)
2. Major calyx (2~3)
3. Renal Pelvis (most superior part of ureter)
4. Ureter
5. Urinary Bladder
6. Urethra
1-5 are lined with transitional, 6 is lined with tansitional and others. |
|
|
Term
| What are the layers of the ureter and urinary bladder? |
|
Definition
1. Mucosa (transitional epithelium, lamina propria)
2. Muscularis (Upper 2/3's has 2 layers, lower 1/3 and urinary bladder has 3)
3. Advantitia
*serosa is on the most superior part of the urinary bladder |
|
|
Term
| What are the muscularis layers in the urinary track? |
|
Definition
1. Inner longitudinal
2. Middle Circular
3. Outer longitudinal in the lower 3rd |
|
|
Term
| Describe the flow of urine from the urinary bladder |
|
Definition
1. Urinary bladder
2.internal urethral sphincter
3.External urethral sphincter
4.urogenital diaphragm
5.Spongy urethra |
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