| Term 
 | Definition 
 
        | Work in the periphery and affect prostaglandin synthesis |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Work in the central nervous system and bind to the mu, kappa, and delta receptors |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: Antipyretic, nonopiod analgesics Ind: mild pain. fever
 Act: inhibits prostaglandin synthesis, no significant anti-inflammatory properties or GI toxicity
 ADRs: hepatic failure, hepatoxicity
 |  | 
        |  | 
        
        | Term 
 
        | Cyclooxygenase inhibitors (COX 1) |  | Definition 
 
        | Present in all tissues, protects gastric mucosa, supports renal function, promotes platelet aggregation (GOOD) |  | 
        |  | 
        
        | Term 
 
        | Cyclooxygenase inhibitors (COX 2) |  | Definition 
 
        | At site of tissue injury and brain. Mediates inflammation, pain, fever response (BAD) |  | 
        |  | 
        
        | Term 
 
        | Aspirin (acetylsalicylic acid, ASA) |  | Definition 
 
        | T: antipyretics, nonopioid analgesics P: salicylates
 Ind: inflammatory disorders, mild to moderate pain, prophylaxis of transient ischemic attacks and MI
 ADRs: dyspepsia, epigastric distress, nausea, naphylaxis, alaryngeal edema,
 |  | 
        |  | 
        
        | Term 
 
        | ibuprofen (Advil, Nuprin) * |  | Definition 
 
        | T: antipyretics, antirheumatics, nonopioid analgesics, P: nonopioid analgesics
 Ind:  mild to modeate pain or dysmenorrhea, inflammatory disorders
 Action: inhibits prostaglandin synthesis
 ADRs: headache, constipation, dyspepsia, nausea, vomiting, anaphylaxis
 |  | 
        |  | 
        
        | Term 
 
        | naproxen (Anaprox, Aleve) |  | Definition 
 
        | T: nonsteroidal anti-inflammatory agents, antipyretics P: nonopioid analgesics
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: antipyretics, antirheumatics, nonopioid analgesics, nonsteroidal anti-inflammatory agents P: nonopioid analgesics
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: antirheumatics, nonsteroidal anti-inflammatory agents |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: antirheumatics P: nonsteroidal anti-inflammatory agents
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: antirheumaticsm nonsteroidal anti-inflammatory agents |  | 
        |  | 
        
        | Term 
 
        | diclofenac (Voltaren, Cataflam) |  | Definition 
 
        | T: T: nonopioid analgesics, non-steroidal anti-inflammatory agents |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T:antirheumatics, nonopioid analgesics P: pyranocarboxylic acid
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: nonsteroidal anti-inflammatory agents, nonopioid analgesics P: pyrroziline carboxylic acid
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | enhance efficacy of other agents, add analgesia, treat concurrent symptoms |  | 
        |  | 
        
        | Term 
 
        | propoxyphene (Darvocet, Darvon) |  | Definition 
 
        | T: opioid analgesics P: opioid agonists, opioid agonists/nonopioid analgesic combinations
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: allergy, cold, and cough remedies, antitussives, opioid analgesics P: opioid agonists
 |  | 
        |  | 
        
        | Term 
 
        | hydrocodone (Vicodin, Lorcet, Norco)* |  | Definition 
 
        | T: allergy, cold, and cough remedies, opioid analgesics P: opioid agonists/nonopioid analgesic combinationsin combination with nonopioid analgesics (aceta/asp/ibu) managing moderate to severe pain
 Act: binds to opiate receptors in CNS
 ADRs: confusion, dizziness, sedation, hypotension, constipation, dyspepsia, nausea
 Ind:
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: opioid analgesics P: opioid agonists, opioid agonists/nonopioid analgesic combinations
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: analgesics (centrally acting) 
 Ind: moderate to severe pain
 Act: binds to mu opioid receptors, inhibits reuptake of serotonin and norepinephrine in the CNS
 ADRs: seizures, dizziness, headache, somnolence, constipation, nausea
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Brand new, not needed for test, but... |  | 
        |  | 
        
        | Term 
 
        | morphine (MS Contin, Avinza)* |  | Definition 
 
        | T: opioid analgesic P: opioid agonists
 Ind: severe pain, pilmonary edema, associated with MI
 Act: binds to opiate receptors in the CNS,
 ADRs: confusion, sedation, hypotension, constipation, respiratory depression
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: allergy, cold, cough remedies, opioid analgesics P: opioid agonists
 Ind: moderate to severe pain
 Act: binds to opiate receptors in the CNS
 ADRs: confusion, sedation, hypotension, constipation
 |  | 
        |  | 
        
        | Term 
 
        | oxycodone (Roxicodone, OxyContin) |  | Definition 
 
        | T: opioid analgesics P: opioid agonists, opioid agonists/nonopioid analgesic combinations
 |  | 
        |  | 
        
        | Term 
 
        | fentanyl (Sublimaze, Duragesic) |  | Definition 
 
        | T: opioid analgesics P: opioid agonists
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: opioid analgesics P: opioid agonists
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: opioid analgesics P: opioid agonists
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: opioid analgesics P:opioid agonists/antagonists
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: opioid analgesics P: opioid agonists/antagonists
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: opioid analgesics P: opioid agonists/analgesics
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: opioid analgesics P: opioid agonists/antagonists
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: opioid analgesics P: opioid agonists
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | raspberry flavored T: opioid analgesics
 P: opioid agonists
 |  | 
        |  | 
        
        | Term 
 
        | fentanyl buccal (Fentora) |  | Definition 
 
        | T: opioid analgesics P: opioid agonists
 |  | 
        |  | 
        
        | Term 
 
        | fentanyl buccal soluble film (Onsolis) |  | Definition 
 
        | T: opioid analgesics P: opioid agonists
 |  | 
        |  | 
        
        | Term 
 
        | opioid-induced side effects |  | Definition 
 
        | constipation, nausea/vomiting, sedation, respiratory depression |  | 
        |  | 
        
        | Term 
 
        | methylnaltrexone (Relistor) |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: antidotes (for opioids) P: opioid antagonists
 |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: anesthetics-topical/locall, antiarrhythmics |  | 
        |  | 
        
        | Term 
 
        | bupivicaine (Marcaine, Sensorcaine) |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: general anesthetics Ind: induction of general anesthesia
 Act: short-acting hypnotic,
 ADRs: apnea, bradycardia, hypotension, burning, pain, stinging
 |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: antianxiety agents, sedative/hypnotics, muscle relaxants P: benzodiazepines
 |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: vasculat headache suppressants P: 5-HT, agonists
 Ind: acute treatment of migraine attacks
 Acts: selective agonist of 5-HT specific vascular serotonin receptor sites, causing vasoconstriction in large intracranial arteries
 ADRs: dizziness, vertigo, tingling, warm sensation, injection site reaction
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T:vascular headache suppressants P: 5-HT, agonists
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: vascular headache suppressants P: 5-HT, agonists
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T:  vascular headache suppressants P: 5-HT, agonists
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: vascular headache suppressants P: 5-HT, agonists
 |  | 
        |  | 
        
        | Term 
 
        | rizatriptan (Maxalt, Maxalt MLT) |  | Definition 
 
        | T: vascular headache suppressants P: 5-HT, agonists
 |  | 
        |  | 
        
        | Term 
 
        | zolmitriptan (Zomig, Zomig ZMT) |  | Definition 
 
        | T: vascular headache suppressants P: 5-HT, agonists
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: antiasthmatics, corticosteroids P: corticosteroids (systemic)
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: antiasthmatics, corticosteroids P: corticosteroids (systemic)
 |  | 
        |  | 
        
        | Term 
 
        | traiamcinolone (Aristocort) |  | Definition 
 
        | T:antiasthmatics, corticosteroids P: corticosteroids (systemic)
 |  | 
        |  | 
        
        | Term 
 
        | methotrexate (Rheumatrex)* |  | Definition 
 
        | T: antineoplastics, antirheumatics, immunosuppressants, P: antimetabolites
 
 Ind: rheummatoid arthritis
 Act: interferes with folic acid metabolism
 |  | 
        |  | 
        
        | Term 
 
        | hydroxychloriquine (Plaquenil) |  | Definition 
 
        | T: antimalarials, antirheumatics |  | 
        |  | 
        
        | Term 
 
        | sulfasalazine (Azulfidine) |  | Definition 
 
        | T: antirheumatics, anti-inflammatories Ind: rheumatoid arthritis
 Act: locally acting anti-inflammatory action
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: antirheumatics P: anti-TNF agents
 Ind: decrease progression, signs and symptoms of rheumatoid arthritis,
 Act: binds to tuumor necrosis factor making it inactive(TNF is a mediator of inflammatory response)
 ADRs: headache, rhinitis, upper respiratory tract infection, injection site reactions
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: antirheumatics P: monoclonal antibodies
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: antirheumatics P: DMARDs, monoclonal antibodies
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: antirheumatics (DMARD) P: interleukin antagonists
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: antirheumatics (DMARDs) P; immune response modifiers
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: analgesics, anticonvulsants, nonopioid analgesics, GABA analogues |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: antidepressants P: selective serotonin and norepinephrine reuptake inhibitors (SSNRIs)
 Ind: major depressive disorders, fibromyalgia
 |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | T:antigout agents, antihyperuricemics P: xanthine oxidase inhibitors
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | T: antigout agents, uricosurics |  | 
        |  | 
        
        | Term 
 
        | sulfinpyrazone (Anturane) |  | Definition 
 | 
        |  |