Term
|
Definition
| hypoglycemia, meds (anticholinergics/ benzos), infections, renal disease, B12 deficiencies, dehydration |
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Term
|
Definition
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Term
|
Definition
| most common type of dementia |
|
|
Term
| pathophysiology of alzheimers |
|
Definition
| neuritic plaques of beta-amyloid protein (inflam), neurofibrillary tangles, cholinergic deficiency |
|
|
Term
| mini-mental state examination |
|
Definition
| 30 point screening questionnaire |
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|
Term
|
Definition
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Term
|
Definition
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Term
|
Definition
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Term
|
Definition
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|
Term
|
Definition
| moderate to severe alzheimer's disease |
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|
Term
| antipsycotics for agitation or psychosis |
|
Definition
| atypical agents may be better tolerated that traditional agents |
|
|
Term
| select antidepressants for non-cognitive symptoms |
|
Definition
|
|
Term
| selective serotonin reuptake inhibitors for depression |
|
Definition
| consider SE profiles when making choices |
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|
Term
| multimodal group training |
|
Definition
| may improve activities of daily living |
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|
Term
| Aricept (donepezil), Razadyne (galantamine), and Exelon (rivastigmine) |
|
Definition
| acetylcholinesterase inhibitors with greater affinity in CNS |
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|
Term
|
Definition
| prevents breakdown of acetylcholine in periphery |
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|
Term
|
Definition
| moderate to severe alzheimers |
|
|
Term
| NMDA receptor antagonist activity |
|
Definition
|
|
Term
|
Definition
| ketamine, dextromethorfan, nitrous oxide, PCP or "angel dust" |
|
|
Term
| normal physiological levels of glutamate |
|
Definition
| are required for memory and learning |
|
|
Term
|
Definition
| prevent further damage to neuronal cells caused by excessive glutamate |
|
|
Term
|
Definition
| when NMDA antag combined with ACHe-I |
|
|
Term
| most common SE acetylcholinesterase inhibitor |
|
Definition
|
|
Term
| serious side effects of acetylcholinesterase inhibitor |
|
Definition
| bradycardia and cholinergic induced bronchospasm (COPD patients) |
|
|
Term
| side effects of acetylcholinesterase inhibitor |
|
Definition
| are opposite of SEs for anticholinergics |
|
|
Term
|
Definition
|
|
Term
|
Definition
| favored for more advanced disease |
|
|
Term
| 23 mg Aricept (donepezil) ....GAHHH these are the same thing! why am I being stupid! |
|
Definition
| extended release and has longer time to Cmax (might reduce SEs/ may increase efficacy???????????????????) |
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|
Term
|
Definition
| is about double that of the 20 mg dose |
|
|
Term
|
Definition
| moderate to severe AD, statistically better than donepezil alone |
|
|
Term
|
Definition
| often results in transient worsening |
|
|
Term
|
Definition
| earlier onset, behavioral issues may be seen before memory loss, may respond to ACHe-I |
|
|
Term
| Dementia with Lewy Bodies |
|
Definition
| presents like Parkinson's, movement disorder occurs within a year of memory issues |
|
|
Term
| highly sensitive to neuroleptics (D2 receptor blockers) |
|
Definition
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Term
|
Definition
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