| Term 
 | Definition 
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        | Term 
 
        | nicotinic acid and nicotinamide |  | Definition 
 
        | derivatives of vitamin B3 |  | 
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        | Term 
 | Definition 
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        | Term 
 
        | function of ascorbic acid (vitamin C) |  | Definition 
 
        | necessary in the body to form collagen in bones, cartilage, muscle, and blood vessels |  | 
        |  | 
        
        | Term 
 
        | ascorbic acid (vitamin C) deficiency |  | Definition 
 | 
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        | Term 
 
        | ascorbic acid (vitamin C) overdose |  | Definition 
 | 
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        | Term 
 
        | nicotinic acid/nicotinamide (vitamin B3 derivatives) deficiency |  | Definition 
 
        | pellagra (skin disease, diarrhea, dementia, depression) |  | 
        |  | 
        
        | Term 
 
        | nicotinic acid/nicotinamide (vitamin B3 derivatives) overdose |  | Definition 
 
        | liver toxicity increased liver enzyme levels in blood
 jaundice
 ascites
 liver failure
 |  | 
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        | Term 
 | Definition 
 
        | risk of the fetus developing a neural tube defect (spina bifida) 
 megaloblastic and macrocytic anemias
 |  | 
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        | Term 
 | Definition 
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        | Term 
 | Definition 
 
        | significant CNS side effects |  | 
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        | Term 
 
        | cyanocobalamin (vitamin B12) deficiency |  | Definition 
 | 
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        | Term 
 
        | function of cyanocobalamin (vitamin B12) |  | Definition 
 
        | helps maintain healthy nerve cells and RBCs 
 also needed to make DNA
 |  | 
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        | Term 
 | Definition 
 
        | required for a vast number of biological processes like vision and cellular growth |  | 
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        | Term 
 | Definition 
 
        | xerophthalmia (dry eye) night blindness/total blindness
 some skin disorders
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | acne certain leukemias
 measles
 malaria
 retinitis pigmentosa
 |  | 
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        | Term 
 | Definition 
 
        | infants can develop a bulging fontanelle 
 adults experience brain tumor-like symptoms
 
 severe toxicity can lead to eye damage, high levels of calcium, and liver damage
 |  | 
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        | Term 
 | Definition 
 
        | aids in absorption of calcium, helping to form and maintain strong bones |  | 
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        | Term 
 | Definition 
 
        | rickets (children) osteomalacia (adults)
 |  | 
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        | Term 
 | Definition 
 
        | hypophosphatemia hyperparathyroidism (due to low vit D)
 hypocalcemia
 psoriasis
 osteomalacia
 renal osteodystrophy
 |  | 
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        | Term 
 | Definition 
 
        | hypercalcemia excess bone loss
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | acts as an antioxidant acts through immunomodulation
 acts through an antiplatelet effect
 |  | 
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        | Term 
 | Definition 
 
        | profoundly affects the CNS and can cause ataxia and peripheral neuropathy |  | 
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        | Term 
 | Definition 
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        | Term 
 | Definition 
 
        | may increase the risk of bleeding problems |  | 
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        | Term 
 | Definition 
 
        | necessary for normal clotting of blood in humans |  | 
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        | Term 
 | Definition 
 
        | defective blood clotting and increased bleeding |  | 
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        | Term 
 | Definition 
 
        | hemorrhagic disease of newborn warfarin reversal
 |  | 
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        | Term 
 
        | rule of thumb with supplements and surgery |  | Definition 
 
        | STOP ALL SUPPLEMENTS 2-3 weeks before any procedure |  | 
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        | Term 
 | Definition 
 
        | hot flashes, night sweats, vaginal dryness, other menopausal symptoms |  | 
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        | Term 
 | Definition 
 
        | mixed <6 month long trials
 |  | 
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        | Term 
 
        | black cohosh side effects |  | Definition 
 
        | headache, GI complaints, weight problems |  | 
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        | Term 
 
        | black cohosh drug interactions |  | Definition 
 | 
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        | Term 
 
        | black cohosh contraindications |  | Definition 
 
        | hx of breast/uterine cancer (very similar to estrogen)
 |  | 
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        | Term 
 | Definition 
 
        | menstrual problems (PMS) menopausal symptoms
 infertility
 acne
 |  | 
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        | Term 
 | Definition 
 
        | some benefit shown for PMS, breast pain, and infertility BUT small poorly designed studies 
 more data needed
 |  | 
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        | Term 
 | Definition 
 
        | GI problems, acne-like rashes, dizziness may affect certain hormone levels
 may affect dopamine system in the brain
 |  | 
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        | Term 
 
        | chasteberry contraindications |  | Definition 
 
        | pregnant women women taking OCP
 women who have a hormone-sensitive condition (ex: breast cancer)
 |  | 
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        | Term 
 | Definition 
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        | Term 
 | Definition 
 
        | no evidence so far 
 more research underway for URIs
 |  | 
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        | Term 
 | Definition 
 
        | asthma, anaphylaxis, rashes |  | 
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        | Term 
 
        | echinacea contraindications |  | Definition 
 
        | allergies (related to plants in the daisy family including ragweed) |  | 
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        | Term 
 | Definition 
 
        | weight loss colds, fever, flu, headaches, nasal congestion, asthma, wheezing
 |  | 
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        | Term 
 | Definition 
 
        | increased risk of heart, psychiatric, and GI problems as well as high blood pressure and stroke |  | 
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        | Term 
 | Definition 
 
        | nausea, anxiety, headache, psychosis, kidney stones, tremors, dry mouth, arrhythmias, heart damage, high blood pressure, restlessness, sleep problems, GI upset, increased urination |  | 
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        | Term 
 
        | What supplement was no longer FDA approved for weight loss as of 2004? |  | Definition 
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        | Term 
 | Definition 
 
        | effective laxative 
 mixed data on lowering cholesterol and preventing heart disease
 |  | 
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        | Term 
 | Definition 
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        | Term 
 | Definition 
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        | Term 
 | Definition 
 
        | high cholesterol HTN
 heart disease
 stomach cancer
 |  | 
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        | Term 
 | Definition 
 
        | no effect on cholesterol mixed data on HTN and atherosclerosis
 no data on cancers
 |  | 
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        | Term 
 | Definition 
 
        | breath/body odor, heartburn, upset stomach, allergic reactions, blood thinner (similar to ASA) |  | 
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        | Term 
 | Definition 
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        | Term 
 | Definition 
 
        | stomach ache nausea
 diarrhea
 |  | 
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        | Term 
 | Definition 
 
        | safely relieves pregnancy-related N/V mixed data on chemo-induced N/V
 |  | 
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        | Term 
 | Definition 
 
        | few if any except with powdered ginger--gas, bloating, heartburn, nausea) |  | 
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        | Term 
 | Definition 
 
        | improve memory prevent Alzheimer's and other types of demetia
 |  | 
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        | Term 
 | Definition 
 
        | promising results for Alzheimer's/dementia BUT larger studies needed 
 may be helpful in reducing claudication symptoms
 |  | 
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        | Term 
 
        | ginko biloba side effects |  | Definition 
 
        | nausea, GI upset, diarrhea, dizziness, allergic skin reactions, can increase bleeding risk 
 uncooked ginko can cause seizures and death (in large quantities)
 |  | 
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        | Term 
 | Definition 
 
        | boost immune system improve mental and physical performance
 erectile dysfunction
 menopausal symptoms
 lower blood glucose
 |  | 
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        | Term 
 | Definition 
 
        | may be effective in lowering blood glucose not enough data on other uses
 |  | 
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        | Term 
 | Definition 
 
        | headaches, sleep problems, GI upset |  | 
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        | Term 
 
        | ginseng contraindications |  | Definition 
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        | Term 
 | Definition 
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        | Term 
 | Definition 
 
        | good evidence to support the use of glucosamine sulfate in treatment of mild to moderate knee osteoarthritis |  | 
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        | Term 
 | Definition 
 
        | GI upset, drowsiness, insomnia, headache, skin reactions, photosensitivity, nail toughening, may increase bleeding risk |  | 
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        | Term 
 | Definition 
 
        | anxiety insomnia
 menopausal symptoms
 |  | 
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        | Term 
 | Definition 
 
        | some evidence for anxiety, but FDA issued warning regarding liver toxicity |  | 
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        | Term 
 | Definition 
 
        | liver damage, hepatitis, liver failure, dystonia |  | 
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        | Term 
 | Definition 
 | 
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        | Term 
 | Definition 
 
        | joint pain skin conditions
 cardiovascular disease
 diabetes
 |  | 
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        | Term 
 | Definition 
 
        | antioxidant, immune-stimulating, and tumor-fighting properties BUT not well-studied 
 NCI studies underway regarding breast cancer prevention
 |  | 
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        | Term 
 | Definition 
 | 
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        | Term 
 | Definition 
 
        | kidney disease (high in potassium) |  | 
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        | Term 
 
        | Where is alpha linoleic acid (ALA) found? |  | Definition 
 
        | flax, soy, walnuts, vegetable oils, etc. |  | 
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        | Term 
 
        | Where are EPA and DHA found? |  | Definition 
 
        | fish and certain nuts (salmon and tilapia--little to no mercury)
 |  | 
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        | Term 
 | Definition 
 | 
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        | Term 
 | Definition 
 
        | lower triglycerides reduce risk of death, MI, arrhythmias, stroke
 lower blood pressure slightly
 |  | 
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        | Term 
 | Definition 
 
        | good evidence to support slight lowering of BP, reduction in TGs, increase in HDL and LDL, reduction of non-fatal MI, fatal MI, sudden death, and all-cause mortality, improved kidney function (with cyclosporine) 
 some evidence with RA
 
 no evidence for diabetes, angina, bipolar disorder, cancer, depression, eczema, menstrual symptoms, UC/Crohn's
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | GI upset, fishy taste may cause increased bleeding (high doses)
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | PMS menopausal symptoms
 eczema
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | mostly small studies some evidence for PMS BUT best studies showed no effect
 |  | 
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        | Term 
 
        | primrose oil side effects |  | Definition 
 | 
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        | Term 
 | Definition 
 | 
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        | Term 
 | Definition 
 
        | supportive evidence for TG and LDL lowering 
 no strong evidence for cardiovascular benefits or diabetes
 |  | 
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        | Term 
 
        | red yeast rice side effects |  | Definition 
 
        | similar to those for lovastatin heartburn, gas, bloating, muscle pain/damage, dizziness, asthma, kidney problems
 |  | 
        |  | 
        
        | Term 
 
        | red yeast rice contraindications |  | Definition 
 
        | liver disease (may increase the risk of bleeding) |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | urinary symptoms associated with BPH chronic pelvic pain, bladder disorders, decreased libido, hair loss, hormone imbalances
 |  | 
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        | Term 
 | Definition 
 
        | not enough evidence to support any uses |  | 
        |  | 
        
        | Term 
 
        | saw palmetto side effects |  | Definition 
 
        | stomach discomfort breast tenderness
 decreased libido
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | depression anxiety
 sleep disorders
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | some effect for mild depressive disorder BUT more studies needed |  | 
        |  | 
        
        | Term 
 
        | St. John's wort side effects |  | Definition 
 
        | photosensitivity, anxiety, dry mouth, dizziness, GI upset, fatigue, headache, sexual dysfunction |  | 
        |  | 
        
        | Term 
 
        | St. John's wort drug interactions |  | Definition 
 | 
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