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Alternative & Complimentary Medicines
N/A
94
Pharmacology
Professional
04/29/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
ascorbic acid
Definition
vitamin C
Term
nicotinic acid and nicotinamide
Definition
derivatives of vitamin B3
Term
cyanocobalamin
Definition
vitamin B12
Term
function of ascorbic acid (vitamin C)
Definition
necessary in the body to form collagen in bones, cartilage, muscle, and blood vessels
Term
ascorbic acid (vitamin C) deficiency
Definition
scurvy
Term
ascorbic acid (vitamin C) overdose
Definition
>2,000 mg/day
Term
nicotinic acid/nicotinamide (vitamin B3 derivatives) deficiency
Definition
pellagra (skin disease, diarrhea, dementia, depression)
Term
nicotinic acid/nicotinamide (vitamin B3 derivatives) overdose
Definition
liver toxicity
increased liver enzyme levels in blood
jaundice
ascites
liver failure
Term
folic acid deficiency
Definition
risk of the fetus developing a neural tube defect (spina bifida)

megaloblastic and macrocytic anemias
Term
folic acid
Definition
form of vitamin B
Term
folic acid overdose
Definition
significant CNS side effects
Term
cyanocobalamin (vitamin B12) deficiency
Definition
pernicious anemia
Term
function of cyanocobalamin (vitamin B12)
Definition
helps maintain healthy nerve cells and RBCs

also needed to make DNA
Term
function of vitamin A
Definition
required for a vast number of biological processes like vision and cellular growth
Term
vitamin A deficiency
Definition
xerophthalmia (dry eye)
night blindness/total blindness
some skin disorders
Term
vitamin A uses
Definition
acne
certain leukemias
measles
malaria
retinitis pigmentosa
Term
vitamin A overdose
Definition
infants can develop a bulging fontanelle

adults experience brain tumor-like symptoms

severe toxicity can lead to eye damage, high levels of calcium, and liver damage
Term
function of vitamin D
Definition
aids in absorption of calcium, helping to form and maintain strong bones
Term
vitamin D deficiency
Definition
rickets (children)
osteomalacia (adults)
Term
vitamin D uses
Definition
hypophosphatemia
hyperparathyroidism (due to low vit D)
hypocalcemia
psoriasis
osteomalacia
renal osteodystrophy
Term
vitamin D overdose
Definition
hypercalcemia
excess bone loss
Term
function of vitamin E
Definition
acts as an antioxidant
acts through immunomodulation
acts through an antiplatelet effect
Term
vitamin E deficiency
Definition
profoundly affects the CNS and can cause ataxia and peripheral neuropathy
Term
vitamin E uses
Definition
controversial
Term
vitamin E overdose
Definition
may increase the risk of bleeding problems
Term
function of vitamin K
Definition
necessary for normal clotting of blood in humans
Term
vitamin K deficiency
Definition
defective blood clotting and increased bleeding
Term
vitamin K uses
Definition
hemorrhagic disease of newborn
warfarin reversal
Term
rule of thumb with supplements and surgery
Definition
STOP ALL SUPPLEMENTS 2-3 weeks before any procedure
Term
black cohosh uses
Definition
hot flashes, night sweats, vaginal dryness, other menopausal symptoms
Term
data on black cohosh
Definition
mixed
<6 month long trials
Term
black cohosh side effects
Definition
headache, GI complaints, weight problems
Term
black cohosh drug interactions
Definition
none reported
Term
black cohosh contraindications
Definition
hx of breast/uterine cancer
(very similar to estrogen)
Term
chasteberry uses
Definition
menstrual problems (PMS)
menopausal symptoms
infertility
acne
Term
data on chasteberry
Definition
some benefit shown for PMS, breast pain, and infertility BUT small poorly designed studies

more data needed
Term
chasteberry side effects
Definition
GI problems, acne-like rashes, dizziness
may affect certain hormone levels
may affect dopamine system in the brain
Term
chasteberry contraindications
Definition
pregnant women
women taking OCP
women who have a hormone-sensitive condition (ex: breast cancer)
Term
echinacea uses
Definition
common cold
flu
URI
Term
data on echinacea
Definition
no evidence so far

more research underway for URIs
Term
echinacea side effects
Definition
asthma, anaphylaxis, rashes
Term
echinacea contraindications
Definition
allergies (related to plants in the daisy family including ragweed)
Term
ephedra uses
Definition
weight loss
colds, fever, flu, headaches, nasal congestion, asthma, wheezing
Term
data on ephedra
Definition
increased risk of heart, psychiatric, and GI problems as well as high blood pressure and stroke
Term
ephedra side effects
Definition
nausea, anxiety, headache, psychosis, kidney stones, tremors, dry mouth, arrhythmias, heart damage, high blood pressure, restlessness, sleep problems, GI upset, increased urination
Term
What supplement was no longer FDA approved for weight loss as of 2004?
Definition
ephedra
Term
data on fiber/flax
Definition
effective laxative

mixed data on lowering cholesterol and preventing heart disease
Term
cheapest form of fiber
Definition
flax seed
Term
fiber/flax side effects
Definition
none
Term
garlic uses
Definition
high cholesterol
HTN
heart disease
stomach cancer
Term
data on garlic
Definition
no effect on cholesterol
mixed data on HTN and atherosclerosis
no data on cancers
Term
garlic side effects
Definition
breath/body odor, heartburn, upset stomach, allergic reactions, blood thinner (similar to ASA)
Term
garlic drug interactions
Definition
some anti-HIV meds
Term
ginger uses
Definition
stomach ache
nausea
diarrhea
Term
data on ginger
Definition
safely relieves pregnancy-related N/V
mixed data on chemo-induced N/V
Term
ginger side effects
Definition
few if any except with powdered ginger--gas, bloating, heartburn, nausea)
Term
ginko biloba uses
Definition
improve memory
prevent Alzheimer's and other types of demetia
Term
data on ginko biloba
Definition
promising results for Alzheimer's/dementia BUT larger studies needed

may be helpful in reducing claudication symptoms
Term
ginko biloba side effects
Definition
nausea, GI upset, diarrhea, dizziness, allergic skin reactions, can increase bleeding risk

uncooked ginko can cause seizures and death (in large quantities)
Term
ginseng uses
Definition
boost immune system
improve mental and physical performance
erectile dysfunction
menopausal symptoms
lower blood glucose
Term
data on ginseng
Definition
may be effective in lowering blood glucose
not enough data on other uses
Term
ginseng side effects
Definition
headaches, sleep problems, GI upset
Term
ginseng contraindications
Definition
careful in diabetics
Term
glucosamine uses
Definition
osteoarthritis
Term
data on glucosamine
Definition
good evidence to support the use of glucosamine sulfate in treatment of mild to moderate knee osteoarthritis
Term
glucosamine side effects
Definition
GI upset, drowsiness, insomnia, headache, skin reactions, photosensitivity, nail toughening, may increase bleeding risk
Term
kava uses
Definition
anxiety
insomnia
menopausal symptoms
Term
data on kava
Definition
some evidence for anxiety, but FDA issued warning regarding liver toxicity
Term
kava side effects
Definition
liver damage, hepatitis, liver failure, dystonia
Term
kava drug interactions
Definition
Parkinson's drugs
Term
noni uses
Definition
joint pain
skin conditions
cardiovascular disease
diabetes
Term
data on noni
Definition
antioxidant, immune-stimulating, and tumor-fighting properties BUT not well-studied

NCI studies underway regarding breast cancer prevention
Term
noni side effects
Definition
liver disease
Term
noni contraindications
Definition
kidney disease (high in potassium)
Term
Where is alpha linoleic acid (ALA) found?
Definition
flax, soy, walnuts, vegetable oils, etc.
Term
Where are EPA and DHA found?
Definition
fish and certain nuts
(salmon and tilapia--little to no mercury)
Term
What are the omega 3's?
Definition
ALA
EPA
DHA
Term
omega 3 uses
Definition
lower triglycerides
reduce risk of death, MI, arrhythmias, stroke
lower blood pressure slightly
Term
data on omega 3's
Definition
good evidence to support slight lowering of BP, reduction in TGs, increase in HDL and LDL, reduction of non-fatal MI, fatal MI, sudden death, and all-cause mortality, improved kidney function (with cyclosporine)

some evidence with RA

no evidence for diabetes, angina, bipolar disorder, cancer, depression, eczema, menstrual symptoms, UC/Crohn's
Term
omega 3 side effects
Definition
GI upset, fishy taste
may cause increased bleeding (high doses)
Term
primrose oil uses
Definition
PMS
menopausal symptoms
eczema
Term
data on primrose oil
Definition
mostly small studies
some evidence for PMS BUT best studies showed no effect
Term
primrose oil side effects
Definition
headache, GI upset
Term
red yeast rice uses
Definition
lower cholesterol
Term
data on red yeast rice
Definition
supportive evidence for TG and LDL lowering

no strong evidence for cardiovascular benefits or diabetes
Term
red yeast rice side effects
Definition
similar to those for lovastatin
heartburn, gas, bloating, muscle pain/damage, dizziness, asthma, kidney problems
Term
red yeast rice contraindications
Definition
liver disease (may increase the risk of bleeding)
Term
saw palmetto uses
Definition
urinary symptoms associated with BPH
chronic pelvic pain, bladder disorders, decreased libido, hair loss, hormone imbalances
Term
data on saw palmetto
Definition
not enough evidence to support any uses
Term
saw palmetto side effects
Definition
stomach discomfort
breast tenderness
decreased libido
Term
St. John's wort uses
Definition
depression
anxiety
sleep disorders
Term
data on St. John's wort
Definition
some effect for mild depressive disorder BUT more studies needed
Term
St. John's wort side effects
Definition
photosensitivity, anxiety, dry mouth, dizziness, GI upset, fatigue, headache, sexual dysfunction
Term
St. John's wort drug interactions
Definition
many including OCPs
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