anti platlet

monoclonal

Diuretic

Carbonic Anhydrase Inhibitor

reduces the reabsorption of bicarbonate ions in proximal tubule

SFx: hyperchloremic metabolic acidosis, kidney stones, sulfa drug

needs 90% inhibition, treats mountain sickness

anti arrhythmic

binds to adenosine receptor

Iv bolus fo treatment of reentrant supraventricular arrythmias

anti asthmatic

inhaled beta agonist

SFx: tremor, doesn't affect inflammation

quick relief

anti hypertensive

Direct Renin inhibitor

SFx: edema, diarrhea, gerd, elevated uric acid

anti coagulant

fibrinolytic

clot buster

must be sure it is it is not a hemmorage

Anti hypertensive/ Diuretic

K sparing

INDIRECT Aldosterone inhibitor

inhibits liminal Na transport in collecting tubule

SFX: hyperkalemia

anti arrhythmic

delayed rectifier K channel blocker

delays repolarization of K channels of phase 2 and 3

SFx: pulmonary fibrosis, photodermatitis, thyriod issues

anti coagulant

anti platelet

inhibits cyclooxygenase

irreversable

Atenolol

Anti hypertensive/ anti arrhythmic

Beta blocker

Mech: blocks beta receptor in heart, blocks beta renin release

SFX: fatigue, tremor, bronchoconstriction

anti asthmatic

long term inhaled corticosteroid

SFx: immunosuppression

anti anginal

inhibits fast inward na current

Sfx: increase QT can lead to torsades

Diuretic

Carbonic Anhydrase Inhibitor

reduces the reabsorption of bicarbonate ions in proximal tubule

SFx: hyperchloremic metabolic acidosis, kidney stones, sulfa drug

needs 90% inhibition, treats mountain sickness

Anti hypertensive/ Diuretic

Loop diuretic

inhibits Cl reabsorption in thick, ascending loop of Henle

SFX: hypokalemia, sulfa drug

smoking cessation

anti depresent

start 1 or 2 weeks prior to quitting

anti hypertensive

ACE inhibitor

decreases angiotensin II production

SFx: hyperkalemia, hypotension, dry cough

bad w/ Nsaids, birth defects 2nd and 3rd trimesters

No reflex sympathetic activation

1st choice in patients w/ chf

Anti hypertensive

mixed blocker

reduces vascular tone and heart rate

SFX: blocks both types of adrenergic receptors

antioxidant

Anti hypertensive/ Diuretic

Thiazide diuretic

inhibits Na/Cl reabsorption in distal convoluted tubule

usefule in nephrogenic diabetes insipidus

SFX: sulfa drug, hypokalemia, hyperuricemia

anti lipid

bile acid resin

interfered with absoprtion of lipid vitamins and drugs

Safest anti lipid

Anti hypertensive/ Diuretic

Thiazide diuretic

inhibits Na/Cl reabsorption in distal convoluted tubule

usefule in nephrogenic diabetes insipidus

SFX: sulfa drug, hypokalemia, hyperuricemia

anti platelet

reversible

Anti lipid

PPAR activator

activates peroxisome proliferator activated receptor

reduces plasma triglycerides

SFX: gallstones can lead to myopathy like statins

first choice in severe triglyceridemia

anti hypertensive

Central acting sympahtolytic

CNS alpha 2 agonist

SFX: water/na retention, sedation, sexual dysfunction

dry mouth, constipation

anti platelet

irreversible

blocks adp receptor

diuretic

vasopressin antagonist

mixed v1 and v2 inhibitor

acute treatment of of CHS w/ hyponatremia

Anti asthmatic

histamine release blocker

very safe

anti diuretic

vasopressin agonist

increases permeability of distal convoluted tubule, inserts water channel

3000x affinity, long half-life

anti hypertensive

arterial vasodilator

K channel openor

SFX: hyperglycemia

treats hypertensive emergencies

Ionotropic agent

cardiac glycoside

blocks Na/K atpase in sarcolemma

increases contractility

anti anginal

Ca channel antagonist

affect cardiac fxn, reduce rate of phase 4 depolarization

risk of MI

anti arrhythmic

delayed rectifier K channel blocker

delays repolarization of K channels of phase 2 and 3

SFx: torsades de pointes

pure k blocker

CHF drug

beta agonist

increase heart rate

used only in hospital

CHF drug

beta agonist

increase heart rate

used only in hospital

Diuretic

Carbonic Anhydrase Inhibitor

reduces the reabsorption of bicarbonate ions in proximal tubule

SFx: hyperchloremic metabolic acidosis, kidney stones, sulfa drug

needs 90% inhibition, treats mountain sickness

Anti hypertensive

alpha adrenoceptor blocker

blocks postsynaptic alpha receptors

SFX: headache, sexual dysfunction

anti hypertensive

ACE inhibitor

decreases angiotensin II production

SFx: hyperkalemia, hypotension, dry cough

bad w/ Nsaids, birth defects 2nd and 3rd trimesters

No reflex sympathetic activation

1st choice in patients w/ chf

anti coagulant

heparin

facilitates antithrombin III

inactivates thrombin and factors IXa and Xa

bleeding

Anti hypertensive/ Diuretic

K sparing

DIRECT aldosterone antagonisst

SFX: hyperkalemia, GYNECOMASTIA

used in primary or secondaryt aldosteronism and liver cirrhosis

No CNS effects

Hematopoetic growth factor

erythropoietin

stimulates rbcs in bone marrow

anti platlet

prevents mi

Anti hypertensive/ anti arrhythmic

Beta blocker

Mech: blocks beta receptor in heart, blocks beta renin release

SFX: fatigue, tremor, bronchoconstriction

short acting, IV used when rapid blockage needed

Anti hypertensive/ Diuretic

Loop diuretic

inhibits Cl reabsorption in thick, ascending loop of Henle

SFX: hypokalemia, OTOTOXICITY

NOT A SULFA DRUG

Anti lipid

inhibits cholesterol absorption at brush border

Interferes with NPCILI

administered w/ statins

Myeloid growth factor

enhance neutrophils

bone pain

treats neutropenia associate w/ chemo

Flecainide

anti arrhythmic

high affinity

na channel blocker

effective at low heart rate too

don't use with heart disease

anti asthmatic

long term inhaled corticosteroid

SFx: immunosuppression

anti coagulant

heparin

facilitates antithrombin III

inactivates thrombin and factors IXa and Xa

bleeding

Anti hypertensive/ Diuretic

Loop diuretic

inhibits Cl reabsorption in thick, ascending loop of Henle

SFX: hypokalemia, sulfa drug

Anti hypertensive

Adrernergic neuron blocker

Inhibits NE release

SFX: Water/Na retention, orthostatic hypotension, drowsiness, diarrhea, sexual disfunction

CHF drug

vasodilator

anti hypertensive

arterial vasodilator

releases NO

SFX: angina, arrhythmia, lupus

has 1st pass effect

Anti hypertensive/ Diuretic

Thiazide diuretic

inhibits Na/Cl reabsorption in distal convoluted tubule

usefule in nephrogenic diabetes insipidus

SFX: sulfa drug, hypokalemia, hyperuricemia

anti arrhythmic

delayed rectifier K channel blocker

delays repolarization of K channels of phase 2 and 3

SFx: torsades de pointes

IV

Anti hypertensive/ Diuretic

Thiazide diuretic

inhibits Na/Cl reabsorption in distal convoluted tubule

usefule in nephrogenic diabetes insipidus

SFX: sulfa drug, hypokalemia, hyperuricemia

anti asthmatic

anti cholinergic

blocks hypersensitivity to choline

SFx: dry mouth,

anti copd

anticholinergic

bronchodilation

anti anginal

nitrate

converted to NO

quick relief of angina

sublingual

CHF drug

vasodilator

converted to NO

can have tolerance

venous dilation

anti anginal

nitrate

converted to NO

quick relief of angina

oral

Anti hypertensive

mixed blocker

reduces vascular tone and heart rate

SFX: blocks both types of adrenergic receptors

anti coagulant

direct inhibition of thrombin

from leeches

anti asthmatic

inhaled beta agonist

SFx: tremor, doesn't affect inflammation

quick relief

anti arrhythmic

low na channel blocker

effective at high heart rate

anti hypertensive

ACE inhibitor

decreases angiotensin II production

SFx: hyperkalemia, hypotension, dry cough

bad w/ Nsaids, birth defects 2nd and 3rd trimesters

No reflex sympathetic activation

1st choice in patients w/ chf

anti hypertensive

Angiotensin II receptor blocker

SFX: less cough, agniodema

similar to ace inhibitors

Anti-lipid

Statin

inhibit HMC-CoA Reductace

decreases plasma LDLs

cardio protective

anti diuretic

vasopressin agonist

increases permeability of distal convoluted tubule, inserts water channel

short half-life

Methyldopa

anti hypertensive

Central acting sympahtolytic

CNS alpha 2 agonist

SFX: water/na retention, sedation, sexual dysfunction

dry mouth, constipation

+ Coombs test hematologic immunodeficiency

anti arrhythmic

low na channel blocker

effective at high heart rate

anti hypertensive

arterial vasodilator

opens up K channels, stabilizes resting potentials

SFX: hypertrichosis (hair growth)

potent long lasting

Anti asthmatic

histamine release blocker

very safe

diuretic

Brain natriuretic peptide

iv constant infusion,

anti lipid

over the counter

inhibits lypolysis of triglycerides in adipose tissue

reduces LDLs

increases HDLs

Hepatotoxic at useful dosages

anti anginal

Ca channel antagonist

relax arterial smooth muscle only

SFx: inhibits heart fxn

reduce O2 demand

anti anginal

Ca channel antagonist

relax arterial smooth muscle only

SFx: inhibits heart fxn

reduce O2 demand

anti anginal

nitrate

converted to NO

quick relief of angina

sublingual

anti asthmatic

monoclonal anti IgE antibody

sub Q injection

megakaryocyte growth factor

recombinant IL-11

increases platelet production

treats thrombocytopenia

Myeloid growth factor

enhance neutrophils

bone pain

treats neutropenia associate w/ chemo

longer half life

anti asthmatic

inhaled beta agonist

SFx: tremor, doesn't affect inflammation

quick relief

Anti hypertensive

alpha adrenoceptor blocker

blocks postsynaptic alpha receptors

SFX: headache, sexual dysfunction

anti asthmatic

systemic corticosteroid

(short term or long term)

anti inflammatory

weight gain, adrenal axis problems

anti arrhythmic

Med na channel blocker

affects some low heart rate

may cause lupus

anti copd

alpha proteinase inhibitor

anti hypertensive

ACE inhibitor

decreases angiotensin II production

SFx: hyperkalemia, hypotension, dry cough

bad w/ Nsaids, birth defects 2nd and 3rd trimesters

No reflex sympathetic activation

1st choice in patients w/ chf

Quinidine

anti arrhythmic

med na channel blocker

affects some low heart rate

tinnitis

anti hypertensive

ACE inhibitor

decreases angiotensin II production

SFx: hyperkalemia, hypotension, dry cough

bad w/ Nsaids, birth defects 2nd and 3rd trimesters

No reflex sympathetic activation

1st choice in patients w/ chf

Anti-hypertensive

Adrenergic Neuron Blocking Agents

 blocks uptake/storage of NorEp

SFX:depression, Parkinson's, nasal congestion, stiffness

megakaryocyte growth factor

stimulates thrombopoiten receptors

increase platelets

headache

treats thrombocytopenia

Myeloid growth factor

enhance neutrophils

bone pain

treats neutropenia associate w/ chemo

SFx: fever malaise edema arthralgia

anti arrhythmic

delayed rectifier K channel blocker

delays repolarization of K channels of phase 2 and 3

SFx: torsades de pointes

Anti hypertensive/ Diuretic

K sparing

DIRECT aldosterone antagonisst

SFX: hyperkalemia, GYNECOMASTIA

used in primary or secondaryt aldosteronism and liver cirrhosis

anti coagulant

fibrinolytic

clot buster

must be sure it is it is not a hemmorage

Anti hypertensive

alpha adrenoceptor blocker

blocks postsynaptic alpha receptors

SFX: headache, sexual dysfunction

anti asthmatic

inhaled beta agonist

SFx: tremor, doesn't affect inflammation

quick relief

anti asthmatic

methylxanthine

phosphodiesterase inhibition

prevents nocturnal symptoms

anti asthmatic

anti cholinergic

blocks hypersensitivity to choline

SFx: dry mouth

longer half-life

Anti hypertensive/ Diuretic

Loop diuretic

inhibits Cl reabsorption in thick, ascending loop of Henle

SFX: hypokalemia, sulfa drug

diuretic

vasopressin antagonist

mixed v1 and v2 inhibitor

acute treatment of of CHS w/ hyponatremia

anti asthmatic

long term inhaled corticosteroid

SFx: immunosuppression

Anti hypertensive/ Diuretic

K sparing

INDIRECT Aldosterone inhibitor

inhibits liminal Na transport in collecting tubule

SFX: hyperkalemia

anti hypertensive

ganglionic blocker

blocks ganglion

sympathoplegia/ parasympathoplegia

NO LONGER AVAILABLE

anti hypertensive

Angiotensin II receptor blocker

SFX: less cough, agniodema

similar to ace inhibitors

anti anginal

Ca channel antagonist

affect cardiac fxn, reduce rate of phase 4 depolarization

risk of MI

anti coagulant

vitamin k epoxide inhibitor

inhibits prothrombin, factors VII, IX, X and protein C

inhibited by vitamin k

anti asthmatic

leukotriene modifier

R= blocks receptor

diuretic

osmotic diuretic

not reabsorbed in renal tubules

SFx: Extracellular volume expansion

hyperkalemia, hypernatremia

IV only

Diuresis without naturesis

Anti hypertensive/ anti arrhythmic

Beta blocker

Mech: blocks beta receptor in heart, blocks beta renin release

SFX: fatigue, tremor, bronchoconstriction

anti asthmatic

leukotriene modifier

blocks receptor

Anti hypertensive/ anti arrhythmic

Beta blocker

Mech: blocks beta receptor in heart, blocks beta renin release

SFX: fatigue, tremor, bronchoconstriction

Anti hypertensive/ anti arrhythmic

Beta blocker

Mech: blocks beta receptor in heart, blocks beta renin release

SFX: fatigue, tremor, bronchoconstriction

anti asthmatic

long acting beta agonist

SFx: tremor, tachycardia

long term

anti asthmatic

leukotriene modifier

blocks enzyme