Term
| Cross BBB and accumulate in CSF (first two are commonly used to treat bac. meningitis |
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Definition
| ceftriaxone, ceftotaxime, ceftazidime, cefttazoxime, cycloserine, pens (only if inflamed), chloramphenicol |
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Term
| excreted in bile (first one commonly used in renal failure pts.) |
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Definition
| ceftriaxone, moxifloxacin (FQ), clindamycin, erythromycin, azithromycin, nafcillin |
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Term
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Definition
| doxycycline, quinupristin/dalfopristin |
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Term
| cross-resistance is present among... |
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Definition
| tetracyclines, fluoroquinolones, macrolides, sulfonamides |
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Term
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Definition
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Term
| chelation by divalent and trivalent ions |
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Definition
fluoroquinolones
tetracyclines |
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Term
| drug interactions cause increased serum warfarin levels with |
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Definition
sulfonamides (poteniate effect)
chloramphenicol,ciprofloxacin/ofloxacin (FQ), quinuprisitn/dalfopristin, erythromycin and clarithromycin (macrolides) - All inhibit metabolism |
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Term
| fosfomycin has syngergistic effects with |
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Definition
| aminoglycosides, b-lactams, fluoroquinolones |
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Term
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Definition
| tetracycline, fluoroquinolones, & sulfonamides(kaplan) |
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Term
| used as empiric therapy. these are resistant to most b-lactamases |
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Definition
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Term
| accumulate in liver and are contraindicated in pts with hepatic disease |
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Definition
| erythromycin, tetracyclines |
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Term
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Definition
| tetracyclines, aminoglycosides, macrolides |
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Term
| gray baby syndrome is caused by |
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Definition
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Term
| these compete with bilirubin for albumin binding sites, causing jaundice |
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Definition
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Term
| Which antibiotics should be avioded during pregnancy |
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Definition
| tetracyclines, fluoroquinolones, aminoglycosides, and sulfonamides |
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Term
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Definition
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Term
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Definition
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Definition
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Term
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Definition
| aminoglycoside (streptomycin) |
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Definition
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Definition
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