Term
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Definition
| Sympathomimetic, bronchodilator, beta-2 agonist |
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Term
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Definition
| Selective beta-2 agonist that stimulates the adrenergic receptors of the sympathomimetic nervous system causing relaxation of the smooth muscle tissue in the bronchial tree and peripheral vasculature |
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Term
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Definition
| Treatment of bronchospasms in patients with reversible COPD and asthma. Also used in prevention of bronchospasms in patients with exercise-induced asthma. |
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Term
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Definition
| Known history of hypersensitivity. Tachycardia, dysrythmias especially when caused by digitalis. Synergistic with other sympathomimetic medications. |
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Term
| Adverse reactions/Side effects |
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Definition
| Often dose-related and include headache, fatigue, lightheadedness, irritability, restlessness, aggressive behavior, pulmonary edema, hoarseness, nasal congestion, increased sputum, hypertension, tachycardia, dysrhythmias, angina pectoris, palpitations, nausea/vomiting, dry mouth, epigastric pain, and tremors. |
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Term
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Definition
| Tricyclic antidepressants may potentiate vasculature effects. Beta blockers are antagonistic and may block pulmonary effects. May potentiate hypokalemia caused by diuretics. |
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Term
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Definition
| Metered-dose inhaler: 90 ug/metered spray. Solution for aerosolization: 0.5% (5mg/mL), 0.083% (2.5 mg) in 3-mL unit dose nebulizer. |
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Term
Dosage and administration
Adult
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Definition
| Administer 2.5 mg. Dilute in 0.5 mL of 0.5% solution for inhalation with 2.5 mL normal saline in nebulizer and aminister over 10-15 minutes. Metered-dose inhaler: 1-2 inhalations (90-180 ug); wait 5 minutes between inhalations |
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Term
Dose and administration
Pediatrics |
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Definition
| ~20kg; 1.25 mg/dose via hand-held nebulizer or mask over 20 minutes. Over 20 kg: 2.5 mg/dose via hand-held nebulizer or mask over 20 minutes. Repeat once in 20 minutes. |
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Term
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Definition
Onset: 5-15 minutes
Peak: 30 minutes to 2 hours
Duration: 3-4 hours |
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Term
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Definition
| Pregnancy safety: Category C. May precipitate angina pectoris and dysrythmias. In prehospital emergency care, albuterol should be administered only via inhalation. |
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