Term
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Definition
| The study of the interaction of chemicals with living organisms to produce biological effects. |
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Term
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Definition
| ability to chemically connect |
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Term
| Food, Drug, and Cosmetic Act of 1938 |
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Definition
Regulate the manufacture, distribution, advertising, and labeling of drugs.
Required proof of saftey before a durge could be marketed.
Authorized factory inspections.
Started penalties for fraudulent claims and misleading labels. |
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Term
| Comprehensive Druge Abuse Prevention and Control Act of 1970 |
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Definition
Regulated distribution of narcotics and other drugs of abuse
Categorized these drugs according to therapeutic usefulness and potential for abuse.
Named things "controlled substances" and we must now account for meds in the hospital. |
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Term
| Drug Regulation Reform Act of 1978 |
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Definition
| Shortened time to get drugs developed |
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Term
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Definition
| Pays companies to make meds for disease with lower disease rates |
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Term
Drug Enforcement Administration
(DEA) |
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Definition
| enforces the controlled substances |
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Term
| Conditions that must be met for a nurse to give a drug: |
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Definition
Valid Order
Presceiber and nurse must be licensed
RN must KNOW about the drug
Use correct technique and precautions when administering each medication |
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Term
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Definition
| Drugs that are not approved for medical use and have high abuse potentials |
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Term
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Definition
| Drugs that are used medically and have high abuse potentials |
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Term
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Definition
| Drugs with less potential for abuse |
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Term
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Definition
| Drugs with some potential for abuse |
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Term
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Definition
| Products containing moderate amounts of controlled substances |
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Term
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Definition
| Involves drug movement through the body to reach sites of action, metabolism, and excretion |
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Term
| Three Main Pathways for Drug Movement Across Cell Membranes |
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Definition
| Direct Penetration, Protein Channels, Carrier Proteins |
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Term
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Definition
| The transport of drug molecules within the body |
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Term
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Definition
| The method by which drugs are inactivated or biotransformed by the body |
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Term
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Definition
| elimination of a drug from the body |
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Term
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Definition
| Very small amounts given. *Death by decimal* |
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Term
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Definition
| Involves drug actions on target cells and the resulting alterations in cellular biochemical reactions and functions ("what the drug does to the body") |
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Term
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Definition
| Drugs that produce effects similar to those produced by naturally occurring hormones |
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Term
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Definition
| Drugs that inhibit cell function by occupying receptor sites |
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Term
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Definition
| Occur when two drugs with similar pharmacologic actions are taken: A+B=AB |
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Term
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Definition
| Two drugs with different sites of action produce greater effects when taken together: A+B=AB2 |
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Term
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Definition
| One drug with the metabolism or elimination of a second drug may result in intensified effects of the second drug |
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Term
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Definition
| Displacement of one drug from plasma protein-binding sites by a second drug increases the effects of the displaced drug |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| Drugs affect people differently |
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Term
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Definition
| Tested by the FDA; not herbs, etc. |
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Term
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Definition
| Fever associated with administration of a medication |
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Term
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Definition
| An unexpected reaction to a drug that occurs the first time it is given |
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Term
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Definition
| it takes more of a substance for it to work |
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Term
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Definition
| The ability of a substance to cause cancer |
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Term
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Definition
| The ability of a substance to cause fetal defects |
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Term
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Definition
| The liver trying to get rid of things. |
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Term
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Definition
| Right drug, dose, client, route, time |
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Term
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Definition
| Absorption, Distribution, Metabolism, Excretion |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| In the veins; quickest route |
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Term
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Definition
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Term
| 3 Routes of Drug Elimination |
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Definition
| In the feces, urine after metabolism, or urine without prior metabolism |
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Term
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Definition
| Tells what type of drugs and equiptment to use based on size of child |
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Term
| How are pediatric doses measured? |
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Definition
| Based on body surface area |
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Term
| Should older adults be given higher or lower doses of meds? |
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Definition
| Lower, because the drugs last longer and act stronger. |
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Term
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Definition
| No risk demonstrated to fetus |
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Term
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Definition
| No adverse effects in animals. No human studies available. |
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Term
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Definition
| Only given when absolutely needed. Animal studies have shown adverse reactions. No human studies available. |
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Term
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Definition
| Definite fetal risks. May still be given in life threatening conditions. |
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Term
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Definition
| Absolute teratogen. Never used! (Accutane) |
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Term
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Definition
| Drugs tested on young males (18-30). No guarentee on what the outcome will be. |
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Term
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Definition
| Small group of people that have the disease are tested. The size of the group is directly proportional to the prevalance of the disease. |
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Term
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Definition
| It didn't kill the Phase 2 people, so it's tested more broadly. |
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Term
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Definition
| Drug is prescribed, but side effects are reported to the FDA by doctors. (Vioox) |
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Term
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Definition
| Failure to do something that could be expected of the reasonable, prudent nurse. |
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Term
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Definition
| Black outlined drug warnings. Improtant warning information. |
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Term
| How many times should you read a drug lable? |
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Definition
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Term
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Definition
| Used to estimate the surface area of infants and young children (Broslow Tape) |
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Term
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Definition
| Used to estimate the surface area of infants and young children (Broslow Tape) |
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Term
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Definition
| Used to estimate the surface area of infants and young children (Broslow Tape) |
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Term
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Definition
| Individual drugs that represent groups of drugs |
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Term
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Definition
| Individual drugs that represent groups of drugs |
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Term
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Definition
| Capillaries with tight walls which limits the transport of medications in the Central Nervous System |
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Term
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Definition
| Physiological Characteristics that lead to Pharmacokinetic consequences |
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Term
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Definition
| Related to the chemical or official name and is independent of the manufacturer (eg, amoxicillin) |
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Term
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Definition
| Designated and patented by the manufacturer |
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Term
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Definition
| Designated and patented by the manufacturer |
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Term
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Definition
| Laboratory measurement of the amount of a drug in the blood at a particular time |
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Term
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Definition
| The ability of a compound to stimulate the receptor to some action; efficiency |
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