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Aetiology of autism: findings & questions
Article by Rutter
15
Psychology
Graduate
02/23/2015

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Cards

Term
multifactorial disorder
Definition
Although there is good evidence to believe that autism is a _____, an adequate understanding of the genetic and non-genetic causes has yet to be achieved.
Term
rise
Definition
Over recent decades there has been a major _____ in the rate of diagnosed autism.
Term
diagnostic concept
Definition
The main explanation for the rise of diagnosed autism is to be found in better ascertainment and a broadening of the ____.
Term
Rett Syndrome
Definition
Has been shown to be the result, in almost all cases, of a mutant gene on the X chromosome.
Term
extends well beyond
Definition
Twin data show that the genetic liability _____ the traditional core diagnosis of autism to include a wider spectrum of autistic-like-disorders including the broader phenotype.
Term
tuberous sclerosis
Definition
The only single gene condition with an established association with ASD is _____.
Term
tuberous sclerosis
Definition
a rare multi-system genetic disease that causes benign tumors to grow in the brain and on other vital organs such as the kidneys, heart, eyes, lungs, and skin.
Term
Fragile X anomaly
Definition
In a very small proportion of cases of ASD studies have found a link between the _____ and autism.
Term
congenital rubella
Definition
The only other established link (re: Intra-Uterine Infections or Toxins) is that between _____ and autism.
Term
rubella (congenital)
Definition
is a viral infection acquired from the mother during pregnancy. Signs are multiple congenital anomalies that can result in fetal death. Diagnosis is by serology and viral culture. There is no specific treatment. Prevention is by routine vaccination.
Term
firstborn
Definition
It has generally been found that autism tends to be more common in the _____ in sibships of two.
Term
last born
Definition
It has generally been found that autism tends to be more common in the _____ in larger sibships.
Term
monozygotic tiwn
Definition
The evidence indicates that it is not likely that being a _____ constitutes a major risk factor.
Term
against
Definition
The evidence is consistently _____ the MMR hypothesis.
Term
negative
Definition
The findings on the link between Thimerosal ( a preservative in many vaccines) and autism are _____.
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