Term
Diazepam
Adverse drug reaction? |
|
Definition
Benzodiazepine
Extension of therapeutic effect
Sedation |
|
|
Term
Quinidine
Adverse drug reaction? |
|
Definition
Anti-arrhythmia
Extension of therapeutic effect
Cardiac depression |
|
|
Term
Warfarin
Adverse drug reaction? |
|
Definition
Anticoagulant
Extension of therapeutic effect
Bleeding |
|
|
Term
Digitalis
Adverse drug reaction? |
|
Definition
Cardiac glycoside
For CGH but causes nausea and vomiting |
|
|
Term
Ferrous sulfate
Adverse drug reaction? |
|
Definition
| For hemoproteins but causes GI distress |
|
|
Term
Phenytoion
Adverse drug reaction? |
|
Definition
| For seizures but causes gum overgrowth |
|
|
Term
Hexamethonium
Adverse drug reaction? |
|
Definition
Ganglionic blocking agent
For antihypertensive effect but also blocks parasympathetic ganglia |
|
|
Term
Succinylcholine
Adverse drug reaction? |
|
Definition
Neuromuscular blocking agent
Some people have an atypical plasma cholinesterase that does not inactivate the drug at a normal rate |
|
|
Term
Penicillin
Adverse drug reaction? |
|
Definition
| Covalent binding to a protein → immediate anaphylactic or delayed hypersensitivity reactions |
|
|
Term
Opioid analgesics (e.g. codeine)
Adverse drug reaction? |
|
Definition
| CNS drug dependence may manifest as tolerance, physical dependence or psychological dependence |
|
|
Term
Amiodarone
Adverse drug reaction? |
|
Definition
| Chronic exposure → pulmonary fibrosis |
|
|
Term
Cigarettes, anti-cancer drugs, cell phones
Adverse drug reaction? |
|
Definition
|
|
Term
Thalidomide
Adverse drug reaction? |
|
Definition
Administered to pregnant females during 1st trimester to treat morning sickness
Phocomelia (limb abnormalities) in babies
Effective for leprosy |
|
|
Term
Fetal alcohol spectrum disorder and iron deficiency
Adverse drug reaction? |
|
Definition
| Cause of in utero nutritional deficiencies |
|
|
Term
Anti-cancer drugs
Adverse drug reaction? |
|
Definition
| Mutagenesis → development of resistance in tumour (e.g. transporter molecules) |
|
|
