Term
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Definition
| Broad term encompassing variety of incidents that occur within the context of drug therapy that result in problematic outcomes |
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Term
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Definition
An injury resulting from the use of a drug
(includes overdoses and ADRS) and withdrawl |
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Term
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Definition
Response to a drug which is noxious and unintended; occurs at doses typically used for therapy; causal link exists
Type A = predictable
Type B = non predictable |
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Term
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Definition
| Side effect - expected or known outcome |
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Term
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Definition
Mishaps that occur during prescribing, transcribing, dispensing, administering, using (adhering to) and monitoring a drug
May be errors comission or omission
May result in harm, or may be “near misses |
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Term
| Gastric pH absorbtion interaction |
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Definition
| ppI and ketoconazole (alters degree ionization) |
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Term
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Definition
| antacid + floroquinolone form insoluble complexes |
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Term
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Definition
| Cholestrymine and digoxin or thyroid hormone |
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Term
| Majority drug interactions phase 1 or phase 2 metabolism? |
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Definition
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Term
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Definition
urinary pH: acid increases phenobarbital
competition: penicillin + probenicid
quinidine + digoxin
Na + Li |
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