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Advanced Nutrition
Vitamins and Minerals
224
Other
Undergraduate 4
04/20/2010

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Term
What are the two forms of vitamin A?
Definition
(1)Retinoids
(2)Carotenoids
Term
Which of the two forms of vitamin A is in the active form and what is the best source? Can it exhibit a toxicity?
Definition
Retinoids; liver; yes
Term
What are four forms of retinoids?
Definition
(1)Retinol
(2)Retinal
(3)Retinoic acid
(4)Retinyl ester
Term
Carotenoids are considered a ___________.
Definition
Provitamin
Term
Which of the two forms of vitamin A is an antioxidant?
Definition
Carotenoids
Term
Regarding vitamin A, the body can convert ___________ to ___________.
Definition
Carotenoids; retinoids
Term
What are three benefits of carotenoids?
Definition
(1)Not a major toxicity
(2)Sources contain less fat
(3)Antioxidant
Term
What are three forms of carotenoids?
Definition
(1)Beta-carotene
(2)Beta-cryptoxanthin
(3)Alpha-carotene
Term
What are five food sources of retinoids?
Definition
(1)Liver
(2)Fish
(3)Fish oils
(4)Fortified milk
(5)Eggs
Term
What are good food sources of carotenoids? Give five examples.
Definition
Dark leafy green/yellow-orange veggies/fruits.
(1)Sweet potato
(2)Carrots
(3)Squash
(4)Broccoli
(5)Cantaloupe
Term
Can eating liver on a consistent basis cause a vitamin A toxicity? If so, what are two other sources that would be less likely to do so?
Definition
Yes
(1)Milk
(2)Eggs
Term
What vitamin and two minerals make-up the most common world-wide deficiencies?
Definition
(1)Vitamin A
(2)Iron
(3)Iodine
Term
Is the absorption rate of vitmain A the same for both veggies and meat?
Definition
No
Term
Unless meat has _____ with it, you probably won't get maxiumum absorption of vitamin A.
Definition
Fat
Term
What is a benefit of the food sources of carotenoids over retinoids?
Definition
Lower in fat
Term
Vitamin A recommendations are expressed as ___________________ (____).
Definition
Retinol activity equivalents (RAE)
Term
Older units of measure for vitamin A include ____ and ____.
Definition
IU; RE
Term
What is the upper limit of vitmain A?
Definition
3000 micrograms/day
Term
It takes (more/less) carotenoids to create a retinoid.
Definition
More
Term
Although the mechanisms remain unclear, what are seven functions of retinoids?
Definition
(1)Reproduction
(2)Cell growth
(3)Bone metabolism
(4)Cellular differentiation
(5)Visual cycle
(6)Immune function
(7)Cell health - mucus
Term
Explain how having adequate retinoids can improve night blindness.
Definition
Rhodopsin (made of a cis-retinal and an opsin) is a protein bound to vitamin A in the rods of the eye. During a light flash, light hits the rods/rhodopsin, which causes it to break; the cis becomes trans. A message is sent to the brain. The retinal can't recombine with opsin becuase it is still in the trans form, so epithelial cells transform it back to the cis form. Ultimately, this takes longer when deficient in vitamin A, causing night blindness.
Term
What vitamin deficiency is a leading cause of world-wide blindness?
Definition
Vitamin A deficiency
Term
Explain retinoids and cell health.
Definition
They promote mucus production by maintaining the health of cells that line both internal and external surfaces (epithelial cells), which provides a barrier to bacterial infection.
Term
______ is a common cause of blindness in older people.
Definition
ARMD (Age-related macular degeneration)
Term
There is a correlation between which two carotenoids providing more protection against ARMD?
Definition
(1)Lutein
(2)Zeaxanthin
Term
Becuase they are _____________, lutein and zeaxanthin, which are found in the __________, can inhibit oxidation of teh cell membrane and protect the eye against damage.
Definition
Antioxidants; macula
Term
What are four good sources of both lutein and zeaxanthin?
Definition
(1)Romaine lettuce
(2)Broccoli
(3)Corn
(4)Garden peas
Term
Explain the difference between risk of toxicity (or lack thereof) of both retinoids and carotenoids.
Definition
Consuming excessive retinoids can cause a toxicity; although excessive carotenoids can cause a non-threatening toxicity, even in excess, the body will stop converting carotenoids to retinoids when a safe threshold is reached.
Term
What are three function of carotenoids?
Definition
(1)Antioxidant - found in lipid b/c fat-soluble
(2)Cell proliferation/growth/differentiation
(3)May improve gap-junction communication b/w cells (lowers risk of cancer)
Term
A vitamin A deficiency can cause...
Definition
(1)Blindness
(2)Night blindness
(3)Poor dark adaptation
(4)Bitot's spots
(5)Keratomalacia
(6)Xeroderma
(7)Xeropthalmia (dry eyes)
(8)Xerosis
Term
When supplementing vitamin A, you can work around a toxicity by avoiding which of the two forms?
Definition
Retinoids
Term
After stopping the use of large doses of these two vitamins (while still maintaining adequate intake), deficiencies can occur.
Definition
(1)Vitamin A
(2)Vitamin C
Term
Large doses of retinoids in a short time period can lead to what toxicity?
Definition
Hypervitaminosis A
Term
What are five symptoms of hypervitaminosis A?
Definition
(1)Nausea
(2)Vomiting
(3)Double vision
(4)Headache
(5)Dizziness
Term
Amounts as little as ___ to ___ times the RDA can bring on hypervitaminosis A.
Definition
3; 4
Term
Hypervitaminosis A can lead to ________ effects (________ ________).
Definition
Teratogenic; birth defects
Term
What is the name of a carotenoid toxicity?
Definition
Hypercarotenemia
Term
Hypercarotenemia results from excessive amounts of _______/_______/_______ _________, which results in what?
Definition
Carrots; squash; beta-carotene; high amounts of carotenoids in the bloodstream
Term
What is a symptom of hypercarotenemia?
Definition
The skin turns a yellow-orange color
Term
Although questionable, high levels of carotenoids may interfere with what two things?
Definition
(1)Estrogen
(2)Fertility
Term
What are two common forms of vitamin E?
Definition
(1)Tocopherols
(2)Tocotrienols
Term
What is the most biologically active form of vitmain E?
Definition
RRR alpha-tocopherol
Term
Is it normal for a diet analysis to show an inadequate intake of vitmain E?
Definition
Yes
Term
Between tocopherols and tocotrienols, which can be an antioxidant?
Definition
Both
Term
Why is vitmain E so difficult to identify in foods?
Definition
Because there are so many different isomers
Term
Is it better to get vitamin E from food or a supplement? Why?
Definition
Supplement; usually provide the most biologically available form
Term
What vitamin, like vitamin E, is better in supplement form?
Definition
Folate
Term
For the most part, vitamin E is safe, except in which population?
Definition
Pregnent women
Term
Can other forms of vitmain E be converted to RRR alpha-tocopherol?
Definition
Yes, but it's lengthy
Term
What are the two best sources of vitamin E?
Definition
(1)Wheat germ
(2)Plant/veggie oils
Term
What are four functions of vitamin E? Which is the principle function?
Definition
(1)MAINTENANCE OF MEMBRANE INTEGRITY - AS AN ANTIOXIDANT
(2)Antioxidant
(3)Reduce synthesis of cholesterol metabolism
(4)Possible supression of tumor growth and cell proliferation
Term
Which form of vitamin E appears to affect cholesterol metabolism?
Definition
Tocotrienols
Term
Is vitamin E quickly or slowly incorporated into cell membranes?
Definition
Slowly
Term
Typically, which is a better source of tocotrienols - supplements or food?
Definition
Food
Term
Is a vitamin E deficiency common or rare?
Definition
Rare
Term
What illness can a vitamin E deficiency cause?
Definition
Cystic fibrosis
Term
What does vitamin E deficiency cause in infants?
Definition
Anemia
Term
What does vitamin E deficiency cause in adults?
Definition
Neuropathy, myopathy
Term
What are three symptoms of vitamin E deficiency?
Definition
(1)Neurological problems
(2)Myopathy
(3)Hemolytic anemia
Term
What is myopathy?
Definition
Skeletal muscle pain
Term
What is hemolytic anemia and what is a mechanism related to vitamin E?
Definition
Breaking of RBCs; oxidative stress can break-down RBCs b/c of inadequate vitamin E in cell membrane to act as an antioxidant
Term
Vitamin E appears to be one of the (most/least) toxic of the vitamins.
Definition
Least
Term
What are three vitamers of B6?
Definition
(1)Pyridoxine, PNP
(2)Pyridoxal, PLP
(3)Pyridoxamine, PMP
Term
Which of the three vitamers of B6 is the one that all other vitamers become?
Definition
Pyridoxal, PLP
Term
The vitamers of B6 are ____________ and __________ ____________.
Definition
Interchangeable; comparably active
Term
What are two sources of B6?
Definition
(1)Bananas
(2)Fortified cereal
Term
Much of the vitamin originally present in foods can be lost through _________.
Definition
Processing
Term
What are six functions of B6?
Definition
(1)Coenzyme
(2)Decarboxylation
(3)Glycogen degredation
(4)Homocysteine regulation
(5)Racemization
(6)Transamination
Term
What is racemization?
Definition
Making AAs ready to use
Term
Without what three B-vitamins do we have higher levels of homocysteine?
Definition
B6, B9, B12
Term
Higher levels of homocysteine is directly related to what two things?
Definition
(1)Heart disease
(2)Plaque formation
Term
A B6 deficiency is (rare/common).
Definition
Rare
Term
What are seven signs of a B6 deficiency?
Definition
(1)Cheilosis
(2)Fatigue
(3)Glossitis
(4)Hyperhomocysteinemia
(5)Microcytic anemia
(6)Seizures
(7)Sleepiness
Term
What is cheilosis?
Definition
Tissue degredation on the sides of the mouth
Term
What is glossitis?
Definition
Swelling of the tongue
Term
As a medicine, B6 may help with what six things? What hormone plays a role? Which one has the strongest support?
Definition
(1)Autism
(2)Carpel tunnel syndrome
(3)Depression
(4)MORNING SICKNESS
(5)Muscular fatigue
(6)PMS
Serotonin, which promotes feelings of happiness
Term
As a medicine, B6 is (conclusive/inconclusive).
Definition
Inconclusive; although it does help with serotonin levels
Term
Can B12 be stored? If so, where?
Definition
Yes; liver
Term
Where is B12 found naturally?
Definition
In animal sources
Term
All of the forms of B12 have what suffix?
Definition
-cobalamin
Term
Which two forms of B12 are most prevalent in the body?
Definition
(1)Methylcobalamin
(2)5'-deoxyadenosylcobalamin
Term
All naturally occuring B12 is produced by ___________.
Definition
Microorganisms
Term
What are the best sources of B12?
Definition
Meat and meat products
Term
What two populations typically need more B12 and why?
Definition
(1)Elderly
(2)Type II diabetics (metformin)
They don't absorb it well
Term
A B6 (toxicity/deficiency) and a B12 (toxicity/deficiency) lead to permanent nerve damage.
Definition
Toxicity; deficiency
Term
What are three functions of B12?
Definition
(1)Coenzyme
(2)Maintenance of nervous system
(3)RBC synthesis
Term
As a coenzyme, in what two enzymatic reactions is B12 involved?
Definition
(1)Conversion of homocysteine to methionine
(2)L-methylmalonyl CoA to Succinyl CoA
Term
Which of the two B12 coenzyme-enzymatic functions is part of the Crebs Cycle?
Definition
L-methylmalonyl CoA to Succinyl CoA
Term
Which of the two B12 coenzyme-enzymatic functions explains RBC synthesis?
Definition
L-methylmalonyl CoA to Succinyl CoA
Term
Which part of the nervous system does B12 aid in maintaining?
Definition
Myelin sheaths
Term
(Inadequate absorption/inadequate dietary intake) is responsible for the majority of B12 deficiency seen in the US.
Definition
Inadequate absorption
Term
B12 deficiency typically occurs in what two populations?
Definition
(1)Strict vegetarians
(2)Infants/young children
Term
A toxicity of _______ can mask a B12 deficiency.
Definition
Folate
Term
What are the stages of a B12 deficiency?
Definition
Serum level diminishes-->cell concentration diminishes-->biochemical deficiencies occur-->anemia
Term
What type of anemia occurs with a B12 deficiency?
Definition
Megaloblastic/macrocytic anemia
Term
Deficiencies of folate and B12 both can cause what?
Definition
Megaloblastic/macrycytic anemia
Term
What are the two biochemical deficiencies that occur with a B12 deficiency?
Definition
(1)Decreased RBCs
(2)Increased homocysteine
Term
Increased homocysteine increases the risk of what?
Definition
Heart disease
Term
Explain why fatigue occurs with anemia.
Definition
The RBCs can't adequately carry oxygen, which means less ATP is produced.
Term
In macrocytic anemia, the RBCs are very (small/large).
Definition
Large
Term
What are six symptoms of a B12 deficiency?
Definition
(1)Concentration loss
(2)Fatigue
(3)Palpitations
(4)Shortness of breath
(5)Skin pallor
(6)Parasthesia
Term
What is parasthesia?
Definition
Tingling and numbness
Term
What is the toxicity of B12?
Definition
No clear toxicity from massive doses of B12 has ever been recorded
Term
What is the upper limit of B12?
Definition
None established
Term
Define macromineral.
Definition
Major mineral; required in amounts > 100 mg/day
Term
Define micromineral.
Definition
Trace mineral; required in amounts < 100 mg/day
Term
What's the relationship between calcium and hypertension?
Definition
Can lower blood pressure
Term
What is the most abundant mineral in the human body?
Definition
Calcium
Term
Which has more calcium: 1/4 c. almonds or 1/2 c. ice-cream? What's the principle here?
Definition
1/4 c. almonds; just becuase it's dairy doesn't mean it's the best source of calcium
Term
When do we reach peak bone mass?
Definition
24 years
Term
Who is more likely to develope osteoporosis: men or women?
Definition
Women
Term
How does smoking relate to calcium?
Definition
Reduces intestinal absorption
Term
How does alcohol consumption relate to calcium? Explain.
Definition
Reduces intestinal absorption of calcium through an inhibition of vitamin D in the liver
Term
What is a good, general recommendation for calcium?
Definition
~1000mg/day
Term
Women lose calcium from bones during _________.
Definition
Lactation
Term
Does milk with a higher fat content (ie whole milk) have more calcium?
Definition
No
Term
Name two food sources of calcium from each category: dairy, seafood, fruits/veggies, fortified foods.
Definition
Dairy: (1)milk, (2)yogurt
Seafood: (1)salmon, (2)sardines w/ bones
Fruits/veggies: (1)broccoli, dried fruit
Fortified foods: (1)cereal, (2)OJ
Term
Better mineral bioavailability absorption will come from _______ sources.
Definition
Animal
Term
What are six poor sources of calcium?
Definition
(1)Meats
(2)Grains
(3)Nuts
(4)Spinach
(5)Rhubarb
(6)Swiss chard
Term
Why are some veggies poor sources of calcium?
Definition
They are high in oxalic acid, which binds the calcium and prevents its absoprtion.
Term
What are four substances that enhance calcium absorption?
Definition
(1)Vitamin D
(2)Sugars
(3)Sugar alcohols
(4)Protein
Term
What are five substances that inhibit calcium absorption?
Definition
(1)Fiber
(2)Phytate
(3)Oxalate
(4)Zinc/magnesium
(5)Unabsorbed fatty acids
Term
What three nutrients enhance urinary calcium excretion?
Definition
(1)Sodium
(2)Caffeine
(3)Protein
Term
The absorption of what two nutrients may be inhibited by excessive calcium?
Definition
(1)Iron
(2)Fatty acids
Term
99% of total body calcium is used for what?
Definition
Mineralization of bone
Term
What are the two types of bone, what part of the bone do the make-up, and what percentage of total bone in the body do they represent?
Definition
(1)Cortical; outer layer; 75-80%
(2)Trabecular; interior; 20-25%
Term
1% of total body calcium is ___________ and is essential for many processes.
Definition
Nonosseous
Term
What are seven functions of nonosseous calcium?
Definition
(1)Blood clotting
(2)Enzyme regulation
(3)Nerve conduction
(4)Muscle contraction
(5)Weight management
(6)Reduces blood pressure
(7)May reduce the risk of colon cancer
Term
Nonosseous calcium functions as a _________ in enzyme regulation.
Definition
Cofactor
Term
Which one of the nonosseous calcium functions is questionable?
Definition
Weight management
Term
How does nonosseous calcium reduce the risk of colon cancer?
Definition
Calcium binds with bile acids and free fatty acids which are promoters of colon cancer
Term
The greatest benefit from bone modeling by calcium occurs during _________ and __________.
Definition
Childhood; adolescence
Term
Calcium deficiency in children is known as ________ and is (reversible/irreversible).
Definition
Rickets; reversible
Term
What is one of the first signs of a calcium deficiency?
Definition
Tetany
Term
What are three symptoms of tetany?
Definition
(1)Muscle pain
(2)Spasms
(3)Numbness and tingling in hands/feet
Term
A calcium deficiency can cause what three things besides tetany?
Definition
(1)Hypertension
(2)Colon cancer
(3)Obesity/increased body weight
Term
What does calcium do concerning blood pressure?
Definition
Aids w/ vasodilation of arteries
Term
Besides calcium, what vitamin and what mineral also cause rickets when deficient?
Definition
Vitamin D; phosphorous
Term
What is the adult deficiency of calcium called. Is it reversible or irreversible?
Definition
Osteomalacia; not reversible
Term
Intakes of calcium in amounts up to ______ mg daily appear to be safe for most individuals.
Definition
2500
Term
Is a calcium toxicity common or rare?
Definition
Rare
Term
What are two symptoms of a calcium toxicity?
Definition
(1)Constipation
(2)Headaches
Term
Excessive calcium intake may increase the risk of what?
Definition
Developing calcium-containing kidney stones
Term
A calcium toxicity can cause what condition? Explain what this is.
Definition
Hypercalcemia; when the calcium level in the blood is constantly above the normal status
Term
Like calcium, a toxicity of _______ is called hypercalcemia.
Definition
Vitamin D
Term
Calcium is a (micromineral/macromineral).
Definition
Macromineral
Term
T/F If you begin taking prenatal vitamins prior to pregnancy, you may experience less nausea during pregnancy.
Definition
True
Term
Zinc is a (micromineral/macromineral).
Definition
Micromineral
Term
T/F Zinc is believed to help reduce the severity and duration of the common cold by 3 days.
Definition
True
Term
Concerning zinc, the (more/less) you consume, the (more/less) you absorb.
Definition
More; less
Term
The (darker/lighter) the meat, the more zinc is available.
Definition
Darker
Term
T/F With zinc, you don't tend to see problems with marginal deficiencies.
Definition
False-you do
Term
Zinc from plant sources is (lower/higher) in content and is absorbed to a (lesser/greater) extent when compared to animal sources.
Definition
Lower; lesser
Term
List two very good sources of zinc and give examples of each.
Definition
(1)Red meat (organ meat)
(2)Seafood (oysters, mollusks)
Term
List three "other good animal sources" of zinc.
Definition
(1)Poultry
(2)Pork
(3)Dairy
Term
Although not the best way to get zinc, what are three good plant sources of zinc?
Definition
(1)Whole grains
(2)Veggies
(3)Nuts/seeds
Term
Zinc is a component of numerous ________ enzymes.
Definition
Metallo
Term
T/F Enzymes from a few enzyme classes have been shown to require zinc.
Definition
False; enzymes from every enzyme class
Term
Besided being a component of numerous metallo enzymes, lists eight more functions of zinc.
Definition
(1)Antioxidant (2)Immune fxn (3)Skin integrity (4)Wound healing (5)Bone formation (6)Supports normal growth and development during pregnancy, childhood, adolescence (7)Sexual maturation dduring adolescence (8)Maintain sense of taste
Term
How does zinc maintain sense of taste?
Definition
It's a component of gustin, a protein involved in taste acuity
Term
_____ and _____ may help with behavior/concentration during childhood.
Definition
Zinc; iron
Term
Sometimes people are diagnosed with _____ when really they are deficient in _____ and _____.
Definition
ADHD; zinc; iron
Term
What are nine symptoms of a zinc deficiency?
Definition
(1)Slow growth
(2)Decreased appetite
(3)Poor wound healing
(4)Hair loss
(5)Taste abnormalities
(6)Hypogonadism
(7)Frequent infections
(8)Night blindness
(9)Skin lesions
Term
Taste abnormalities due to a zinc deficiency can lead to what?
Definition
Weight loss and even anorexia
Term
Zinc deficiency is common in who?
Definition
Elderly
Term
The UL for zinc for healthy adults is ___mg/day, which you probably (will/will not) get from food?
Definition
40; will not
Term
Intakes of 150 mg/day of zinc can do what four things?
Definition
(1)Lower copper status
(2)Alter iron fxn
(3)Reduce immune fxn
(4)Reduce HDL levels
Term
List seven symptoms of a zinc toxicity.
Definition
(1)Diarrhea
(2)Abdominal cramping
(3)Vomiting
(4)Jaundice
(5)Chills
(6)Fever
(7)Hymolytic anemia
Term
Hemolytic anemia can cause _______, ____ _____, and _____/_____ ________.
Definition
Fatigue; pale gums; rapid/labored breathing
Term
Iron is a (micromineral/macromineral)
Definition
Micromineral
Term
_____ deficiency is the greatest deficiency in the world.
Definition
Iron
Term
What is the name for iron toxicity?
Definition
Hemochromatosis
Term
What is the most common cause of poisoning deaths in kids under 6 in the US?
Definition
Accidental iron overdose
Term
Hemochromatosis typically occurs in _____ _____.
Definition
Older men
Term
What are the two forms of dietary iron in food?
Definition
(1)Heme
(2)Nonheme
Term
Heme iron is a component of what two things?
Definition
(1)Hemoglobin
(2)Myoglobin
Term
In what form is 2/3 of all the iron in our bodies found?
Definition
Hemoglobin
Term
About 50-60% of the iron in meat is ____.
Definition
Heme
Term
This kind of iron is usually bound to components in foods.
Definition
Nonheme iron
Term
What must happen in order for the absoprtion of nonheme iron to occur?
Definition
It must be enzymatically freed int he GI tract
Term
Where is nonheme iron primarily found?
Definition
In plant products
Term
Nonheme iron is (easier/more difficult) to absorb than heme iron.
Definition
More difficult
Term
Which vitamin aids in the absorption of nonheme iron?
Definition
Vitamin C
Term
T/F It's entirely possible to get 100% absorption of iron, especially from meat.
Definition
False; never absorb 100% of iron, not even from animal sources
Term
What are three good sources of iron?
Definition
(1)Organ meats
(2)Raw clams
(3)Oysters
Term
Overall absorption of iron from the US diet is estimated at about ___%-___%.
Definition
10; 18
Term
Does a person's iron status affect their iron absorption?
Definition
Yes
Term
What are six functions of iron?
Definition
(1)Assists with oxygen transport in blood - hemoglobin
(2)Assists in transport of oxygen to muscle cells - myoglobin
(3)Cofactor for enzymes involved in energy metabolism
(4)Catalase that combats free radicals as part of an antioxidant enzyme system
(5)Immune fxn
(6)Pro-oxidant
Term
What is the name for an iron deficiency?
Definition
Iron deficiency anemia
Term
What are four symptoms of an iron deficiency?
Definition
(1)Yellow eyes
(2)Cold
(3)Fatigue
(4)Pale
Term
What are eight things that can impair iron absorption?
Definition
(1)Phytates
(2)Polyphenols
(3)Phosvitin
(4)Calcium
(5)Zinc
(6)Manganese
(7)Nickel
(8)Coffee
Term
What are three sources of phytates?
Definition
(1)Legumes
(2)Rice
(3)Whole grains
Term
What is a source of polyphenols?
Definition
(1)Tannins from tea/coffee
Term
What is phosvitin?
Definition
A protein, containing phosphorylated serine residues found in egg yolk
Term
If you want to drink coffee, but want to prevent the malabsorption of iron as much as possible, when should you not drink it?
Definition
With or just after a meal
Term
What are the two forms of vitamin D?
Definition
(1)Ergocalciferol
(2)Cholecalciferol
Term
What ultraviolet ray is responsible for synthesizing vitamin D?
Definition
UVB rays
Term
What is the best time of day to make vitamin D from sunlight?
Definition
Midday or between 10am and 3pm
Term
What factors will inhibit the synthesis of vitamin D?
Definition
Sunscreen, skin pigment, season/latitude/time of day, aging, skin grafts, hepatic failure, chronic renal failure
Term
Are tanning beds a reliable way to synthesize vitamin D?
Definition
No
Term
What is the toxicity of vitamin D called?
Definition
Hypervitaminosis D
Term
Can you get a vitamin D toxicity from sunlight?
Definition
No, excess vitamin D3 is destroyed by sunlight
Term
What are two trace minerals of greatest concern for vegetarians? Why?
Definition
(1)Iron
(2)Zinc
With the elimination of meat and increased intake of phytate-containing legumes and whole grains, the absorption of both iron and zinc is lower with vegetarian than with nonvegetarian diets
Term
What are the best food sources of zinc?
Definition
Red meat, seafood
Term
What are the best food sources of iron?
Definition
Liver, red meat, shellfish
Term
Which form of iron is better absorbed?
Definition
Heme
Term
What are the enhancers of iron?
Definition
Meat, poultry, fish, ascorbic acid, alcohol, retinol, carotenes
Term
What are inhibitors of iron?
Definition
Phytic acid, polyphenols/tannins (tea and coffee), soy protein, egg, calcium, phosphate salts, antacids
Term
What food preparation techniques can improve iron status?
Definition
Using iron cookware, the consumption of iron-containing foods concurrently with sources of ascorbic acid-containig foods while limiting inhibitory foods to between meals, selecting lower-phytate foods
Term
Where does most zinc come from in the US?
Definition
Animal products
Term
What are plant foods rich in zinc?
Definition
Legumes, whole grains, nuts, seeds
Term
What mineral competes with iron and zinc?
Definition
Calcium
Term
What are two reasons for why scholarly articles are often inconclusive?
Definition
(1)Genetics - still don't know enough
(2)Can't safely make definite conclusions
Term
List concrete function statements regarding B6, B9, B12.
Definition
B9 & B12 lower homocysteine; inadequate 6, 9, 12 cause elevated homocysteine; increased plasma homocysteine is risk factor for CVD; treatment of hyperhomocystenemia w/ 6, 9, 12 shown to reduce thrombin formation; elevated homosysteine contributes to atherosclerosis; B12 w/ other B vitamins reduces insulin resistance in patients w/ metabolic syndrome/markers for oxidative stress/inflammation; synthesis and repair of DNA is a well-known function of B9; B9 and possibly B6 and B12 deficiencies are related to cancer; higher B12 significantly associated w/ better outcome for treatment of major depression; adequate B9 shown to reduce incidence of neural tube defects
Term
What is the recommendation for vitamin D for breastfeeding mothers?
Definition
400 IU
Term
What are natural food sources of vitmain D?
Definition
Salmon, sardines, mackerel, tuna, cod liver oil, shitake mushrooms, egg yolk
Term
What is phytic acid, what foods are common sources, and what effect does it have on iron and zinc?
Definition
A compound found naturally in plant cells; plant sources; inhibits the absorption
Term
What is homocysteine?
Definition
A sulfur-containing amino acid precursor of methionine
Term
Who might you recommend (B6), B9, and B12 supplementation to?
Definition
Elderly (50+), vegetarians, in conjunction w/ pharmcotherapy for depression, type II diabetes, CVD
Term
From the "checklist," list four symptoms of hypthyroidism.
Definition
(1)Leg cramps
(2)Feeling cold
(3)Brittle hair and nails
(4)Constipation
Term
What is euthyroid sick syndrome?
Definition
Occurs when a nonthyroid illness (infection, synthetic hormones, inflammatory condition) causes an irregularity of thyroid levels; thyroid itself not diseased/inflamed; other factors are causing imbalance of thyroid hormones
Term
What are the functions/potential benefits of viramin D?
Definition
Determinant of mortality; anti-inflammatory; immune-modulating; maintains blood pressure and cardiovascular health; reduces risk of diabetes and metabolic syndrome; aids in calcium absorption; decreases risk of falling; improved muscle function; benificial role in cancer prevention/survival; reduces risk of autoimmune diseases (MS); improves dimentia; prevent rickets (infants)
Term
What are symptoms of hypervitaminosis D?
Definition
Fatigue, nausea, vomiting, weakness
Term
Symptoms of hypervitaminosis D are probably caused by the resultant ______________.
Definition
Hypercalcemia
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