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Adv H 1.4 Nerve Impulse
Glossary FCs
28
Biology
Not Applicable
10/07/2022

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Term
membrane potential
Definition
a difference in electrical charge on the two sides of the membrane
Term
Resting membrane potential
Definition
a state where there is no net flow of ions across the membrane
Term
depolarisation
Definition
a change in the membrane potential to a less negative value inside.
Term
action potential
Definition
a wave of electrical excitation along a neuron's plasma membrane
Term
Neurotransmitters
Definition
signal molecules that bind to their receptors at a synapse
Term
Neurotransmitter receptors
Definition
ligand-gated ion channels at a synapse
Term
depolarisation
Definition
caused by entry of positively charged ions into a neuron
Term
voltage-gated sodium channels
Definition
when opened allow more sodium ions to enter the cell down their electrochemical gradient
Term
voltage-gated sodium channels
Definition
open when membrane is sufficiently depolarised
Term
voltage-gated potassium channels
Definition
open to restore the resting membrane potential
Term
sodium-potassium pump
Definition
restores the sodium and potassium ions back to resting potential levels
Term
vesicles containing neurotransmitter to fuse with the membrane / release of neurotransmitter into the synapse
Definition
event when the action potential reaches the end of the neuron
Term
retina
Definition
the tissue at the back of the eye which converts light into electrical signals
Term
Rod cells
Definition
cells that are sensitive to changes in light intensity and are particularly useful for vision in areas of low light intensity
Term
cone cells
Definition
cells that are sensitive to specific colours (wavelengths) of light
Term
retinal
Definition
light-absorbing molecule in rod cells of retina
Term
opsin
Definition
membrane protein on rod cells that binds to retinal
Term
rhodopsin
Definition
visual pigment formed when opsin and retinal combine
Term
photoexcited rhodopsin
Definition
formed when retinal absorbs a photon of light
Term
transducin
Definition
G-protein that is activated by photoexcited rhodopsin
Term
100s
Definition
number of transducin proteins activated by single photoexcited rhodopsin
Term
phosphodiesterase (PDE)
Definition
enzyme activated by transducin
Term
1
Definition
number of phosphodiesterase enzymes activated by single transducin
Term
phosphodiesterase (PDE)
Definition
catalyses the hydrolysis of a molecule of cyclic AMP (cAMP)
Term
1000s
Definition
number of cAMPs broken down by one phosphodiesterase (PDE)
Term
closure of ion channels
Definition
effect of reduction in cGMP concentration
Term
increase in membrane potential / triggers nerve impulses
Definition
effect of closing the ions channels in neurons in the retina
Term
high degree of amplification of signal (1>100s>1>1000s)
Definition
what causes rod cells to be able to respond to low intensities of light.
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