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Adv H 1.3
RR Quiz Qs
28
Biology
Not Applicable
04/05/2022

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Term
What is the name of the model that describes the plasma membrane structure?
Definition
fluid mosaic
Term
Which type of interaction of R groups holds proteins in a cell membrane?
Definition
Hydrophobic
Term
What are the 2 types of cell membrane proteins (determined by their position)?
Definition
Peripheral and transmembrane
Term
Which type of R group interaction holds peripheral proteins on the surface of the cell membrane?
Definition
Hydrophilic
Term
Give 2 examples of hydrophilic interactions of R groups involved in holding peripheral proteins on the surface of the cell membrane
Definition
ionic and hydrogen bonds
Term
Give 2 examples of molecules which can pass through the bilayer of the cell membrane by diffusion.
Definition
carbon dioxide and oxygen
Term
Define facilitated diffusion.
Definition
Passive transport of molecules across the through some transmembrane proteins.
Term
What controls ligand-gated channels?
Definition
the binding of signal molecules
Term
What controls voltage-gated channels?
Definition
changes in ion concentration
Term
What types of molecules cannot cross the barrier created by the phospholipid bilayer?
Definition
ions and most uncharged polar molecules / hydrophilic
Term
How do transporter proteins transfer substances across the membrane?
Definition
bind to the specific substance to be transported and undergo a conformational change to transfer the solute across the membrane.
Term
What is the function of ATPases?
Definition
ATPases hydrolyse ATP
Term
What two things are needed to cause active transport (movement of molecules against their concentration gradient)?
Definition
ATP & membrane protein.
Term
Function of sodium potassium pump
Definition
actively transports sodium ions out of the cell and potassium ions into the cell
Term
Name the important integral protein pump involved in creating an ion gradient across a cell.
Definition
Sodium potassium pump.
Term
Name the protein pump, found in animal cells, that accounts for much of the organism's basal metabolic rate (about 25% of your BMR)
Definition
Sodium potassium pump.
Term
What causes a membrane potential (an electrical potential difference).
Definition
a difference in electrical charge on the two sides of a membrane
Term
What is the general function of ion pumps?
Definition
to establish and maintain ion gradients
Term
From where does the sodium potassium pump get its energy?
Definition
from the hydrolysis of ATP
Term
Which direction does the sodium potassium pump the ions?
Definition
sodium is pumped OUT of the cell, potassium is pumped IN to the cell
Term
Which conformation of the Na/K pump has a high affinity for Na?
Definition
dephosphorylated / without phosphate attached
Term
Which conformation of the Na/K pump has a high affinity for K?
Definition
phosphorylated / with phosphate attached
Term
How many Na ions are transported by one cycle of the Na/K pump?
Definition
3
Term
How many K ions are transported by one cycle of the Na/K pump?
Definition
2
Term
What happens to the Na/K pump when it is phosphorylated / dephosphorylated?
Definition
the conformation of the protein changes
Term
As well as the ions' concentration gradients what else does the Na/K pump create?
Definition
an electrical gradient
Term
How is the sodium gradient created by the Na/K pump useful in the intestinal epithelial cells?
Definition
it is used to drive the active transport of glucose.
Term
How does the glucose symport protein work ?
Definition
sodium ions move into the cell, DOWN their concentration gradient, through the symport which simultaneously pumps the glucose into the cell AGAINST its concentration gradient
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