Term
|
Definition
B1 selective
vasodilation via NO release endothelial cells |
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Term
|
Definition
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Term
|
Definition
non-selective
blocks B2 in bronchiole smooth m.
life threatening constriction in COPD, asthma |
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Term
|
Definition
| decrease aqueous humor production decreases IOP in glaucoma |
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Term
|
Definition
| reduce performance anxiety |
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Term
|
Definition
| tx: HTN, angina, CHF, SV tachycardia, atrial flutter, MI, migraine prophylaxis |
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Term
|
Definition
| HTN, CHF, improves survival in acute MI |
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Term
|
Definition
B1 and partial B2 antagonist
chronic or emergency HTN
can cause orthostatic hypotension |
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Term
|
Definition
longest acting
combined with diuretic
HTN and angina |
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Term
|
Definition
| HTN, MI, migraine, topical for glaucoma (with pilocarpine) |
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Term
|
Definition
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Term
|
Definition
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Term
|
Definition
| least selective B1 selective |
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Term
|
Definition
longest 1/2 life of B1 selective
HTN, angina, MI, arrhythmia, migraine |
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Term
|
Definition
ultra short acting
tx in critically ill patients sensitive to bradycardia, controlling arrhythmias associated with thyroid storm |
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Term
|
Definition
widely used
HTN, angina, MI |
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Term
|
Definition
most B1 selective
NO vasodilation
HTN |
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Term
|
Definition
blocks uptake into vesicles
NE accumulates in cytoplasm
degraded by MAOs = decrease NE release
drop in BP and cardiac rate |
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Term
|
Definition
blocks NE release and displaces NE from storage vesicles
gradual decrease of BP and HR |
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Term
|
Definition
inhibits tyrosine hydroxylase, preventing catecholamine synthesis
rare use: pheochromocytoma |
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|
Term
Pindolol
Penbutolol
Acebutolol
Labetalol |
|
Definition
| intrinisic sympathetic activity (partial agonist) |
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|
Term
|
Definition
| tx HTN, angina, arrhythmias, myocardial infarction, glaucoma, migraines |
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|
Term
Acebutolol
Metoprolol
Esmolol
Atenolol
Nebivolol |
|
Definition
|
|
Term
|
Definition
lower lipid solubility, cannot enter CNS
therefore decrease adverse effects such as sedation, sleep disturbances, and depression |
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