Term
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Definition
| potent vasoconstricor and cardiac stimulant. physiological consequences depend on method of administration and dose |
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Term
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Definition
| drug of choice for anaphylactic shock or hypersensitivity |
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Term
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Definition
| can actually make "shock" worse by decreasing blood flow to vital organs |
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Term
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Definition
| give subQ or IV for emergency asthma, but there are more selective agents available |
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Term
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Definition
tx open angle glaucoma
decreases production increase flow aqueous humor |
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Term
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Definition
| given in emergency cardiac arrest or complete heart block |
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Term
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Definition
rapidly metabolized by MAO and COMT
action brief IV |
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Term
Epinephrine
Rapid IV infusion |
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Definition
blood pressure rapidly peaks (S>D)
B-1 increases rate and force
A-1 increases peripheral R |
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Term
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Definition
decrease Diastolic (B2 vasodilates skeletal muscle)
B2= more sensitive than A |
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Term
Epinephrine
slow infusion/subQ |
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Definition
| heart rate, CO, SV, force all increase |
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Term
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Definition
released from adrenal medulla during exercise:
increase blood to muscles/lungs, bronchodilate, energy |
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Term
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Definition
| increase blood glucose, lactate levels, glucagon, fatty acids= increased energy |
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Term
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Definition
litte effect on B2 therefore no bronchodilation
increase HR, force, BP, R |
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Term
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Definition
only use:
increase BP in acute hypotensive state |
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Term
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Definition
potent activator of B receptors
little effect on A receptors
increase HR, FC (B1)
decrease peripheral R (B2) |
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Term
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Definition
| can cause palpitations, sinus tachycardia, serious arrhythmia |
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Term
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Definition
resists MAO, but not COMT
once used as bronchodilator
stimulate HR in emergency bradycardia, but pacemaker is preferred |
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Term
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Definition
activates D1 and D2
only given IV |
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Term
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Definition
low doses activate D1:
dilates renal, coronary, mesenteric arteries
increase GFR, renal Q, Na excretion |
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Term
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Definition
low doses at D2
inhibit release endogenous NE |
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Term
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Definition
high doses can activate B1 on HEART
positive inotropic
can also activate a1 increase PR |
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Term
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Definition
tx severe CHF with oliguria and normal peripheral vascular resistance
beneficial in shock |
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Term
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Definition
D1 selective
lower BP in severe HTN
short duration |
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Term
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Definition
synthetic catecholamine
primarily B1 agonist
some alpha agonist and antagonist |
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Term
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Definition
| short term tx cardiac decompensation after surgery, CHF, or acute MI |
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Term
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Definition
| increases CO and SV without much effect on HR |
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Term
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Definition
| increase force of contraction more than rate when compared to isoproterenol |
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