Term
| What two hormones are excreted by the adrenal medulla? |
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Definition
| Epinephrine and norepinephrine |
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Term
| What hormones are excreted by the adrenal cortex |
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Definition
Corticosteroids
Glucocorticoids and mineralocorticoids |
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Term
What does Glucocorticoid hormone regulate? |
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Definition
Carbohydrates, protein, and lipid metabolism and inhibit the release of adrenocorticotropic hormone (corticotropin) |
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Term
| What does mineralocorticoid regulate? |
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Definition
electrolytes and water balance; primary mineralocorticoid is aldosterone
Think regulating Minerals |
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Term
| Aldosterones primary role? |
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Definition
| To maintain normal levels of sodium in the blood by causing sodium to be reabsorbed from the urine back into the blood in exchange for potassium and hydrogen ions. |
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Term
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Definition
| Disorder characterized by abnormally increased secretion of the adreno- corticosteroid |
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Term
|
Definition
Potentially life-threatening condition caused by partial or complete failure of adrenocortical function, with resulting decrease in glucocorticoid, mineralocorticoid, and androgenic hormones.
It is a chronic disease of hyposecretion of steroids |
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Term
| Which glucocorticoid would you use for women in premature labor to accelerate fetal lung maturation? |
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Definition
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Term
Glucocorticoid
Contraindications |
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Definition
| Cataracts, glaucoma, peptic ulcers, mental health problems, and diabetes mellitus |
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Term
Glucocorticoid
Interactions |
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Definition
Potassium wasting diuretics (thiazides, loop)
Aspirin and NSAIDS ^ chance of gastric ulcers
Anticholinesterase drugs
Antidiabetics
Thyroid hormones and Antifungal
Oral contraceptives, ^ half-life of adrenal drugs
Anticoagulants
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Term
| What medication would you use to treat Addison's disease? |
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Definition
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Term
| What medication would you use to treat Cushing's disease? |
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Definition
Aminoglutethimide
(Antiadrenal drug)
Hepatotoxicity, GI upset, jaundice and hypotension |
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Term
|
Definition
Mineralocorticoid
Treat Addison's disease, treat salt-losing adrenogenital syndrome
Adverse effects related to water retention effect
Heart failure, hypertension, elevated intracranial pressure |
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Term
|
Definition
Intermediate-acting Glucocorticoid
Methylprednisolone, prednisolone, and triamcinolone
Used for antiinflammatory and immunosuppressant
Treat chronic respiratory diseases |
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Term
|
Definition
Injectable glucocorticoid drug
Long-acting
Not given to children under 28 days |
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Term
| When is the best time to administer Glucocorticoids? |
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Definition
between 6 am and 9 am
To minimize the amount of adrenal suppression while levels are at their peak |
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Term
| Prednisone (glucocorticoid) and Fludrocortisone (minerialocorticoid) Is recommended to be administered orally with? |
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Definition
| milk and/or food to help minimize GI upset |
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Term
| Why would you instruct a patient to take their long-acting glucocorticoid on alternating days? |
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Definition
| To minimize the adrenal suppression |
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Term
| A patient is prescribed aminoglutethimide. Because of this prescription, you can assume the patient has? |
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Definition
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Term
| During long-term corticosteroid therapy, the nurse will monitor the patient for Cushing's syndrome, which is manifested by? |
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Definition
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Term
| During long-term corticosteroid therapy, the nurse will monitor the patient's laboratory results for adverse effects, such as? |
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Definition
Decreased serum potassium levels
Increased sodium levels
Hyperglycemia |
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Term
Signs of adrenal insufficiency |
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Definition
anorexia, nausea, weakness, and fatigue
Others: hypotension and hypoglycemia |
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