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Adele's Pharmacology
Block4 Pharm
26
Other
Not Applicable
02/12/2007

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Cards

Term
Describe Muscarinic receptors
Definition
g-protein coupled
M1,M3,M5 = stimulatory (salivary glands!)
M2, M4 = inhibitory (heart/bronchioles)
Term
Describe nicotinic receptors
Definition
ion channels
N1=Nm
N2=Nn
Term
Describe nicotinic receptors
Definition
ion channels
N1=Nm
N2=Nn
Term
What is the rate limiting step of dopmaine, E, and NE synthesis?
Definition
tyrosine hydroxylase
Term
What does activation of beta 1 in kidneys cause?

What does activation of beta 1 in pituitary cause?
Definition
renin secretion

ADH secretion
Term
Ciliary body has __ receptors upon stimulation have what effect?
Definition
beta 1

increase aqueous humor
Term
Ciliary body has __ receptors which upon stimulation have what effect?
Definition
beta 1

increase aqueous humor
Term
What is used to treat chronic glaucoma?
Definition
beta 1 blockers
Term
Radial muscle has __ receptors. Activation causes __.
Definition
alpha 1

mydriasis
Term
Stimulation of H1 receptors causes
Definition
increase in calcium
Term
Bladder sphincter has __ receptors that cause contraction

Detrussor muscle has __ receptors for relaxation
Definition
alpha 1

beta 2
Term
What receptor should you stimulate to inhibit an erection?
Definition
Alpha 2
Term
Dopamine
Definition
activates beta 1, then alpha 1, but NOT beta 2
Term
Norepinephrine
Definition
actvates beta 1, alpha 1, alpha 2 (but NOT beta 2!)
Term
Isoproterenol
Definition
purely beta
Term
Isoproterenol
Definition
purely beta
Term
What receptors does skeletal muscle have?
Definition
alpha 1 and beta 2; low doses of epinephrine activate beta 2 (dilation), higher doses activate alpha 1 (constriction)
Term
What drug do you give to treat Parkinson's? why?
Definition
L-dopa; it can cross the BBB
Term
Dopamine is used to treat __.
Definition
cardiogenic shock
Term
Dopamine is used to treat __.
Definition
cardiogenic shock

increases force of contraction more than rate
Term
phenylephrine
Definition
alpha 1 agonist

nasal decongestant
Term
phenylephrine
Definition
alpha 1 agonist
Term
clonidine
Definition
alpha 2 agonist
Term
albuterol
Definition
beta 2 agonist
Term
Dobutamine
Definition
beta 1 agonist
Term
Dobutamine
Definition
beta 1 agonist
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