Term
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Definition
1.2mg orally (this is two 0.6 mg tablets) followed by 0.6 mg in 1 hour (new recommendation is to not exceed a total of 1.8 mg - or 3 doses) |
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Term
| Brand name for colchicine |
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Definition
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Term
| Brand name for indometachin |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| Which is the DOC NSAID for acute gout attacks? |
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Definition
Indomethacin was 1st NSAID approved and is the traditional DOC, however, it is more toxic thatn ibuprofen (increase risk for GI toxicity) and has psyciatric side effects including confusion, depression, psychosis. |
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Term
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Definition
| Statement. Not a question. |
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Term
| Colchicine is a substrate of? |
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Definition
CYP 3A4; if using a moderate 3A4 inhibitor, the maximum dose is 2 tablets (x1) - and wait at least 3 days prior to an additional dose. |
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Term
| Precaution of taking colchicine with statins? |
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Definition
Myopathy and rhabdomyolysis have been reported in patients taking colchicine with a statin or fibrate. Try not to use with gemfibrozil and have patients monitor muscle pain/soreness. |
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Term
| How to take colcichine when having an acute gout attack. |
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Definition
At the first sign of an attack, take 2 tablets. You can take 1 more tablet in one hour. Do not use more than this amount.
Taking too much colchicine can lead to serious side effects. |
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Term
| Should one stomach upset be concerned about colchine? |
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Definition
Colchicine causes significant GI upset. One should not take the 2nd dose (during a gout attack) if one has an upset stomach, nausea or diarrhea. |
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Term
| How long should one wait before doing a round of colchicine treatment? |
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Definition
Wait at least 3 days before initiating another course of colchicine therapy.
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