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Actinic Keratosis (asterisked)
n/a
57
Medical
Graduate
08/26/2012

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Term
What is acidic keratosis?
Definition
Skin-colored to reddish brown or yellowish black ill-defined macule or papule wth a dry adherent scale
Term
How is Actinic Keratosis treated?
Definition
Liquid nitrogen or excision with biopsy if hypertrophic (hypertrophic has high chance of skin cancer)
Term
Why should we treat actinic keratosis?
Definition
Some purists state this is already an early stage of squamous cell carcinoma so it's best to get rid of it
Term
What are some common sites of actinic keratosis?
Definition
Dorsum of the hands, scalp (particularly in men with thinning hair)
Term
There is a strong correlation between Actinic Keratosis and what?
Definition
Sun exposure
Term
What is the second most common form of skin cancer in the US?
Definition
Squamous cell carcinoma (700,000 cases/year)
Term
Where is squamous cell carcinoma most commonly found?
Definition
Head, neck, or hands of older patients
Term
How is squamous cell carcinoma treated?
Definition
Biopsy of lesion is necessary for diagnosis and treatment
Term
What is the most common form of skin cancer in the world?
Definition
Basal cell carcinoma
Term
Describe the appearance of basal cell carcinoma
Definition
Translucent, pearly white dome shaped papule (HIGH YIELD)
Term
How is basal cell carcinoma treated?
Definition
Excisional biopsy if the lesion is small enough
Term
What is the most dangerous and most serious lesion that dermatologists deal with?
Definition
Malignant melanoma (not very common)
Term
What is the prognosis for melanoma?
Definition
Portenially curable with early diagnosis and treatment
Term
What do we look for to determine whether or not to biopsy?
Definition
the ABCDE's of melanoma (HIGH YIELD) - Asymmetry, Border irregularity, Color variability, Diameter, Evolving
Term
How is melanoma treated?
Definition
All suspicious lesions should be biopsied
Term
What kind of advice should you give patients for avoiding skin cancer?
Definition
Minimize sun exposure, individuals with high risk should use sunscreen daily, know that some medications can cause an increase in sun sensitivity, start kids early
Term
What characteristic features indicate seborrheic keratosis?
Definition
Stuck on, pigmented, greasy appearance w/ smooth tiny round embedded pearls or rough dry cracked, always well circumscribed border and appears stuck-on
Term
What is the most common age group diagnosed with Seborrheic Keratosis?
Definition
Adults older than 30
Term
Is Suborrheic Keratosis benign or malignant?
Definition
Benign but resembles malignant melanogma
Term
How is Seborrheic keratosis treated?
Definition
Removed for cosmetic purposes via cryosergery or curettage
Term
Is a cutaneous horn benign or malignant?
Definition
Provides no information, must shave off to determine what is underlying, often benign but may be pre-malignant or malignant
Term
What are the features of condrodermatitis nodularis helicis?
Definition
Painful, pearly papule, looks like basal cell carcinoma
Term
Are cafe au lait spots cancerous?
Definition
If 6 or more then NF1
Term
What disease are cafe au lait spots associated with?
Definition
von Recklinghausen's disease (NF-1)
Term
What are are the characteristics of Becker's nevus?
Definition
Brown macule, patch of hair or both
Term
Is halo nevus benign or malignant?
Definition
Benign but can resemble melanoma
Term
What disease is halo nevus sometimes associated with?
Definition
Turner's syndrome (18% of patients) as well as patients with Vitiligo and Melanoma
Term
How do hypertrophic scars differ from keloids?
Definition
Stays within the borders of the trauma and, keloids are larger than the area of trauma to the skin
Term
What causes hypertrophic scars?
Definition
Overgrowth of granulation tissue (type II and later type I collagen)
Term
What are the characteristic features of blue nevus
Definition
Slightly elevated, round, regular nevus, usually <0.5cm w/large amounts of pigment in dermis, scattering blue light due to tindel effect
Term
Is blue nevus benign or malignant?
Definition
Non-cancerous but can be malignant, associated with arising melanoma or melanoma may resemble a blue nevus
Term
What are the characteristics of spitz nevi?
Definition
Hairless, red/reddish-brown, dome shaped papules or nodules w/ a smooth or warty surface, color due to increased vascularity and may bleed from trauma, usually solitary and appears suddenly, needs to be excised
Term
How androgenic alopecia (male pattern baldness) treated?
Definition
Rogaine (topical minoxidil), propecia (finasteride-oral), transplants, weaves
Term
What is trichotillomania?
Definition
Hair loss usually in easily reachable areas, such as the frontoparietal region
Term
What is the cause of trichotillomania?
Definition
Hair is twisted around the finger and pulled or rubbed until extracted or broken
Term
How is trichotillomania treated?
Definition
Consider psychiatric referral
Term
What are the characteristics of alopecia areata?
Definition
Rapid onset total hair loss in sharply defined, usually round area
Term
How is alopecia areata treated in patients older than 10yrs?
Definition
Intralesional glucocorticoid (first line) and/or 5% topical minoxidil solution
Term
What is cherry angioma?
Definition
Bright cherry read, small (pinhead size to 1/4 inch), smooth or can stick out from skin
Term
How is cherry angioma managed?
Definition
No treatment required but may be cosmetically removed
Term
What are the features of Keratoacanthoma?
Definition
Central core, looks like volcano, comes up within 2-3 weeks, lesions are solitary, smooth, dome shaped red papules or nodules w/central keratin plug
Term
What are the three stages of hair growth?
Definition
Catagen (transitional), telogen (resting0, and anagen (growing, 95% of hair)
Term
The hair pull test should result in what?
Definition
Fewer than 6 club hairs extracted
Term
What is telogen effluvium?
Definition
Premature termination of anagen, causing abnormally high number of hairs to enter telogen phase
Term
What are some causes of telogen effluvium?
Definition
High fever from any cause, severe emotional/physical trauma, hypo/hyperthyroidism, crash diets, acute blood loss, childbirth
Term
How long after a traumatic event is hair normally lost?
Definition
2 weeks
Term
What drugs are commonly associated with telogen effluvium or generalized hair loss?
Definition
Coumarin, heparin, propranolol, vit A
Term
What is anagen effluvium?
Definition
Abrupt hair loss from follicles that re in their growing phase, caused by abrupt insult to metabolic/follicular reproductive apparatus, greater hair loss than telogen effluvium
Term
What is androgenic alopecia?
Definition
Male pattern baldness due to progressive shortening of successive angen cycles
Term
What is hirsutism?
Definition
Excessive terminal hair in women that normally appears in men (beards)
Term
What lab tests are first-line in evaluating hirsutism?
Definition
Total and free testosterone levels (TSH and prolactin)
Term
How is hirsutism treated?
Definition
Anti-androgens, glucocorticoids, long acting gonadotropin-releasing hormone analogs
Term
How does alopecia areata differ from tinea capitis?
Definition
Tinea capitis has positive skin test to Tichophyton antigen, is an immune response responsible for intense inflammation
Term
What is alopecia totalis?
Definition
100% loss of scalp hair
Term
What is traction alopecia?
Definition
Prolonged tension created by certain hairstyles, hair rollers, and hot hair straightening combs, may result in temporary or permanent hair loss
Term
What is nail pitting?
Definition
Sharply defined ice pick-like depressions in nail plate
Term
What nail changes are seen in psoriasis?
Definition
Onycholysis (yello scaly debris that elevates nail bed), nail deformity, pitting, oil spot lesions
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