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ABX and pathogens
Understanding ABX and pathogens
35
Health Care
Graduate
09/11/2007

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Term
Erythromycin is effective against _______ organisms and NOT _________ organisms.
Definition
Erythromycin is effective against gram-positive organisms and NOT gram-negative organisms.
Term
Why is Ciprofloxacin not a good choice for bacterial endocarditis?
Definition
does not cover gram-positive Streptococcus viridans
Term
Inhibits cell wall production
Definition
beta lactams (PCN, cephalosporins, carbaoenems)
monobactams (aztreonam)
glycopeptides (vancomycin)
Term
Inhibits protein synthesis
Definition
50S ribosome (macrolides, lincosamides, oxazolidinones)
30S ribosome (aminoglycosides, tetracylines)
Term
Inhibits DNA synthesis
Definition
fluroquinolones and metronidazole
Term
Inhibits folic acid synthesis
Definition
TMP/SMX
Term
Bacteriocidal
Definition
primarily beta lactams and fluroquinolones.
also monobactams, glycopeptides, aminoglycosides and metronidazole
Term
Bacteriostatic
Definition
primarily tetracylines, macrolides
also lincosamides, oxazolidinones, sulfonamides
Term
ABX class for salmonella
Definition
fluroquinolones
Term
ABX class for legionella
Definition
macrolides
Term
ABX active against intracellular organisms
Definition
remember fluroquinolones and macrolides

also tetracylines, TMP/SMX
Term
ABX renal secretion
Definition
beta lactams, monobactams, glycopeptides, aminoglycosides, fluroquinolones and tetracylines
Term
ABX hepatic secretion
Definition
ceftriaxone, macrolides and metronidazole
Term
ABX and Ototoxicity
Definition
aminoglycosides (gentamycin and vancomycic) and minocycline
Term
ABX and nephrotoxicity
Definition
Amphotericin B, aminoglycosides (gentamycin), beta lactams (nafcillin), vancomycin
Term
No ETOH with which ABX
Definition
metronidazole
Term
ABX in red man syndrome
Definition
vanco
Term
ABX in red lobster syndrome
Definition
rifampin
Term
ABX in discolored teeth
Definition
tetracyclines
Term
ABX in loss of red/green color
Definition
ethambutol
Term
ABX in yellow babies
Definition
sulfonamides
Term
ABX in hyperkalemia
Definition
trimethoprim (half of Bactrim)
Term
ABX in hypokalemia
Definition
various PCNs
Term
ABX in c.diff
Definition
aminopenicillins, clindamycin, cephalosporins
Term
fetotoxic ABX
Definition
metronidazole
Term
oral anti-MSSA ABX (methacillin suseptable staph aureus)
Definition
Gold standard: dicloxacillin
Silver: cephalexin
minocycline, doxycycline > TMP/SMX
Term
oral anti-MRSA ABX (methacillin resistant staph aureus)
Definition
linezolid
minocycline, doxycycline > TMP/SMX
Term
oral Anti-psuedomonal ABX
Definition
ciprofloxacin and levofloxacin
Term
oral Anti-VRE ABX (vancomycin-resistant enterococcus)
Definition
linezolid
Term
oral Anti-anerobic ABX
Definition
gold standard = metronidazole or amoxicillin/clavulanate
silver = clincamycin
Term
IV anti-MSSA ABX (methacillin suseptable staph aureus)
Definition
gold = nafcillin
silver = cefazolin
bronze = vancomycin
Term
IV anti-MRSA ABX (methacillin resistant staph aureus)
Definition
gold = vancomycin
Term
IV Anti-psuedomonal ABX
Definition
piperacillin/tazobactam
aztreonam
ceftazidime or cefepime
cipro or levofloxacin
tobramycin
doripenem > meropenem > imipenem
Term
IV Anti-VRE ABX
Definition
linezolid
daptomycin
Term
IV Anti-anerobic ABX
Definition
Gold = betamactim, imipenem, metronidazole
silver = clindamycin
bronze = cephamycin
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