Term
|
Definition
# precursor to gastric lymphoma
# usually regresses with H. pylori tx |
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Term
| Test that detects urease from H. pylori |
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Definition
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Term
| Cells located in the Fundus and Body |
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Definition
Oxyntic cells:
# Chief Cells
# parietal cell |
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Term
| Secretory product of chief cells |
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Definition
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Term
| Secretory product of parietal cells |
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Definition
| Acid and intrinsic factor |
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Term
| Stimulants of acid production |
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Definition
# Ach
# Gastrin
# histamine |
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Term
| Pathway by which Ach stimulates acid secretion |
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Definition
| Phospholipase increase intracellular Ca |
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Term
| Pathway by which gastrin stimulates acid secretion |
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Definition
| Phospholipase increase intracellular Ca |
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Term
| Pathway by which histamine stimulates acid secretion |
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Definition
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Term
| Inhibitory stimuli for acid secretion |
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Definition
# CCK
# secretin
# PGE1
# SST |
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Term
| Cells in the antrum/pylorus |
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Definition
# G cells
# D cells
# mucus gland |
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Term
| Secretory product of G cells |
|
Definition
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|
Term
| stumulus to secrete gastrin |
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Definition
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Term
| Inhibitory stimuli for gastrin |
|
Definition
secretin
acid in the duodenum |
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Term
| Secretory product of D cells |
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Definition
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Term
|
Definition
| Inhibits gastrin and acid release |
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Term
| Secretory product of Brunner's glands and location |
|
Definition
# secrete pepsinogen and alkaline mucus
# located in duodenum |
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Term
|
Definition
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Term
|
Definition
mucus cell hyperplasion
increased rugal folds |
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Term
| Functional outcome of complete vagotomy on solids |
|
Definition
| Delayed emptying of solids |
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Term
| Target of selective vagotomy |
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Definition
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|
Term
| Effect of vagotomy on liquid emptying from stomach |
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Definition
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|
Term
| Method of ameliorating the delayed gastric emptying of solids from stomach caused by a complete vagotomy |
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Definition
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|
Term
| MC problem following a vagotomy |
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Definition
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|
Term
| Biggest risk factors for rebleeding from a UGI bleed at time of EGD |
|
Definition
# spurting blood vessel- 60%
# visible blood vesel- 40%
# diffuse oozing- 30% |
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Term
| Effect of duodenal ulcers based on location |
|
Definition
# anterior- perforate
# posterior bleed |
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Term
| Most frequent complication of duodenal ulcers |
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Definition
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Term
| Type of ulcers a/w type A blood |
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Definition
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|
Term
| Type of ulcers a/w type O blood |
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Definition
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Term
| Type 1 gastric ulcer, cause and management |
|
Definition
# Along lesser curvature
# decreased mucosal protection
# distal gastrectomy including ulcer with Billroth I or II I/- fagotomy |
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|
Term
| Type 2 gastric ulcer, cause, and management |
|
Definition
# along lesser curvature and the duodenum
# Caused by high acid secretion
# distal gastrectomy with Billroth I or II and truncal vagotomy |
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Term
| Type 3 gastric ulcer, cause and management |
|
Definition
# pre-pyloric
# caused by high acid secretion
# distal gastrectomy with Billroth I or II and truncal vagotomy |
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|
Term
| Type 4 gastric ulcer, cause and management |
|
Definition
# high along lesser curvature along the Cardia
# Caused by decreased mucosal selection
# ulcer excision +/- highly selective vagotomy or trucnal vagotomy and pyloroplasty |
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|
Term
| Type 5 gastric ulcer, cause and management |
|
Definition
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|
Term
| Factors a/w increased risk of gastric adenocarcinoma |
|
Definition
# adenomas > 2 cm
# type A blood
# nitrosamines
# chronic atrophic gastritis/pernicious anemia |
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|
Term
| Surgical margin necessary for gastric adenocarcinoma and why |
|
Definition
| # 6 cm because of intramural spread |
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|
Term
| Treatment for gastric lymphoma |
|
Definition
# chemo/RT
# surgery only for complications |
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|
Term
| Success rates of non-op management for SBO |
|
Definition
# pSBO- 65%
# complete SBO- 20% |
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Term
| Metabolic complications of terminal ileum resection |
|
Definition
# decrease bile salt absorption which leads to less colonic water absorption leading to diarrhea
# decrease B12 from decrease B12/IF absorption
# decreased binding of oxalate leading to mor oxalate absorption in the colon causing oxalate kiney stones |
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Term
|
Definition
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|
Term
| Way to diagnose a carcinoid syndrome |
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Definition
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|
Term
| MC benign gastric neoplasm |
|
Definition
| Gist Tumor (gastric leiomyoma) |
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Term
|
Definition
# resection with 1 cm margins
# Add chemotherapy if tumor > 5 cm or > 5-10 mitoses per HPF |
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Term
| Oncogene a/w with most GIST tumors |
|
Definition
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|
Term
| Chemotherapy of choice for GIST tumors |
|
Definition
| Gleevac (tyrosine kinase inhibitor) |
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Term
| Cause and constellation of symptoms of pellagra |
|
Definition
# tryptophan (or niacin) deficiency
# 3 Ds: dermatitis, dementia, diarrhea |
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Term
|
Definition
# flusing
# asthma
# diarrhea
# R-sided valvular dz |
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|
Term
| Sx management for carcinoid syndrome |
|
Definition
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|
Term
| percentage of pt's with small bowel carcinoid who have mult primary sites |
|
Definition
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|
Term
| Percentage of pt's with small bowel carcinoid who have metachronus adenocarcinoma |
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Definition
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|
Term
| Type of cells the produce serotonin |
|
Definition
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|
Term
| Role of chemotherapy for carcinoid syndrome and common agents |
|
Definition
# usually just for unresectable disease
# streptozocin, doxorubicin, 5-FU |
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Term
| Factors a/w failure of fistulas to heal |
|
Definition
# Friends
* Foreign body
* Radiation
* IBD
* Epithelialization
* Neoplasms
* Distal obstruction
* Sepsis/Infection |
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