Term
|
Definition
# superior rectal artery off IMA
# middle rectal artery off internal iliac
# inferior rectal off pudendal off internal iliac |
|
|
Term
| Electrolytes actively secreted by the colon |
|
Definition
|
|
Term
| Innervation of external anal sphincter |
|
Definition
| # inferior rectal branch of internal pudendal nerve and perineal branch of S4 |
|
|
Term
| Managemet of SCC of the anal canal |
|
Definition
# Nigro protocol (Chemo and XRT)
# must check for inguinal adenopathy and FNA anything suspicious; if positive- extend radiation field
# APR for recurrent disease |
|
|
Term
| Avg length of time for malignant transformation of a polyp |
|
Definition
|
|
Term
| Definition of T1 rectal CA and management |
|
Definition
# Confined to submucosa
# can be excised transanally |
|
|
Term
| Definition of T2 rectal CA and management |
|
Definition
#
# APR; do not resect transanally if poor differentiation or neurovasc invasion |
|
|
Term
| Definition of stage III colon CA and management |
|
Definition
# has + node
# chemo, no RT |
|
|
Term
| Management of Stage II rectal CA |
|
Definition
|
|
Term
| Management of stage III rectal CA |
|
Definition
|
|
Term
| Genetic alterations a/w with colon CA |
|
Definition
# 50% have ras mutation
# 85% have absent p53
# 70% have DCC (deleted in colon CA) |
|
|
Term
| Mode of inheritance of FAP |
|
Definition
|
|
Term
| Genetics involved with FAP |
|
Definition
|
|
Term
|
Definition
# polyps present at puberty
# colon CA by age 40 |
|
|
Term
|
Definition
# start at 10-12 yo; stop at 40 if no CA
# flex-sig looking for polyps and EGD looking for duodenal polyps,
# sulindac to makes polyps recede |
|
|
Term
|
Definition
| # Prophylactic total proctocolectomy, mucosectomy and ileoanal pouch followed by lifetime surveillance of remaining rectal mucosa |
|
|
Term
|
Definition
# lynch I: Right sided colon cancer, young
# Lynch II: colon CA + increased risk of ovary, bladder, endometrial and stomach CA |
|
|
Term
| Mode of inheritance of Lynch |
|
Definition
|
|
Term
|
Definition
| DNA mismatch repair gene mutation |
|
|
Term
| Diagnostic criteria of Lynch |
|
Definition
# Amsterdam criteria (3-2-1)
* 3 primary relatives
* over 2 generations
* 1 with cancer < 50 yo |
|
|
Term
|
Definition
# start at 20-25 yo or 10 yrs younger than earliest family member
# Colonoscopy every 2 years until age 40, then annual |
|
|
Term
|
Definition
| Colon CA and desmoid tumors |
|
|
Term
|
Definition
| Colon CA and breain tumors |
|
|
Term
|
Definition
| Polyposis (not CA) and mucocutaneous pigmentation |
|
|
Term
| Best approach if operating for a suspected appy but find Crohn's dz |
|
Definition
| # do appendectomy unless cecum is involved in Crohn's |
|
|
Term
| Management of peri-rectal abscess in Crohns |
|
Definition
|
|
Term
| Effect of total colectomy on extra-intestinal manifestations of UC |
|
Definition
# PSC and arthritis do not improve
# skin and anemia may get better |
|
|
Term
| Genetic association of sacroiliitis |
|
Definition
|
|
Term
|
Definition
| Flagyl and/or short chain fatty acid enemas |
|
|
Term
| Management of pyoderma gangrenosum |
|
Definition
| # dapson and/or steriod (topical or systemic) |
|
|
Term
| Location of anal fissures |
|
Definition
# 10% anterior in women
# nearly all others posterior midline |
|
|
Term
| Management of anal fissures |
|
Definition
# sitz baths
# water and fiber
# can try topic nitroglycerine or botox
# lateral internal sphincterotomy if persists |
|
|
Term
| # Ddx for fissures that are not in midline |
|
Definition
|
|
Term
| Definition of Bowen's dz and manaement |
|
Definition
# intraepidermal SCC (only 5% invasive)
# tx with widel local incision |
|
|
Term
| Definition and diagnosis of perianal Paget's dz |
|
Definition
# rare intra-epidermal neoplasms of apocrine glands with a long pre-invasive phase
# +PAS stain |
|
|
Term
| Diff b/w CD and UC: location |
|
Definition
# CD: small bowel involved
# UC: confined to colon (+backwash ileitis) |
|
|
Term
| Diff b/w CD and UC: anatomic distribution |
|
Definition
# CD: asymetric (skip lesions)
# US: contiguous involvemed started distally and moving proximally |
|
|
Term
| Diff b/w CD and UC: rectal involvement |
|
Definition
# CD: rectal sparing
# UC: most of the time |
|
|
Term
| Diff b/w CD and UC: Gross bleeding |
|
Definition
|
|
Term
| Diff b/w CD and UC: peri-anal dz |
|
Definition
|
|
Term
| Diff b/w CD and UC: Fistulas |
|
Definition
|
|
Term
| Diff b/w CD and UC: Granulomas |
|
Definition
|
|
Term
| Diff b/w CD and UC: layers of bowel involved |
|
Definition
# CD: transmural
# UC: mucosa and submucosa |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Diff b/w CD and UC: location of perforation |
|
Definition
# CD: distal ileum
# UC: transverse colon |
|
|
Term
| Most common post-op morbidity |
|
Definition
|
|
