Term
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Definition
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Term
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Definition
| rbc's with an mcv of less than 80 fL and a diameter of less than 7 u |
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Term
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Definition
| impaired hemoglobin synthesis from ineffective iron utilization, absorption or release; or decreased or defective globin synthesis. |
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Term
| Microcytes are associated with what diseases? |
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Definition
| iron deficiency anemia, thalassemia and anemia of chronic disease. |
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Term
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Definition
| rbc's with an mcv of greater than 100 fL and a diameter greater than 9 u. |
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Term
| What does poikilocytosis mean? |
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Definition
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Term
| What is another name for the sea urchin type or burr cell? |
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Definition
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Term
| A rbc with 10 to 30 spicules or projections evenly distributed over the entire surface is called..? |
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Definition
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Term
| What abnormal cell shape is thought to be the result of an increase in the area of the outer leaflet of the lipid bilayer as compared to the inner layer? |
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Definition
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Term
| On a stained smear, an echinocyte could be artifactual. What would be the causes of this? |
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Definition
| the alkaline glass effect, or ATP depletion in stored blood. |
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Term
| Which abnormal red cell shape is associated with plasma chemical abnormalities such as dehydration, uremia, liver disease in newborns. |
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Definition
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Term
| An abnormal red cell that lacks the area of central pallor and has a decreased surface to volume ratio. |
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Definition
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Term
| What conditions could cause spherocytes? |
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Definition
| Hereditary spherocytosis, hemolytic anemias |
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Term
| Hereditary spherocytosis is associated with a membrane protein defect. What protein is usually defective? |
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Definition
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Term
| What causes non-hereditary spherocytes? |
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Definition
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Term
| What kind of macrocytes are formed following acute hemorrhage or hemolysis? |
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Definition
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Term
| What abnormal red cell morphology is associated with recovery from acute blood loss, hemolytic anemias, parenchymal liver disease |
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Definition
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Term
| What is a more common name for a drepanocyte? |
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Definition
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Term
| Disordered erythrocyte maturation results in what abnormal cell morphology? |
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Definition
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Term
| An oval to elongated cell with variable diameter is called... |
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Definition
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Term
| The drepanocyte or sickle cell is associated with what abnormal hemoglobin? |
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Definition
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Term
| What are two forms of Drepanocytes? |
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Definition
| holly leaf form and sickle cell |
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Term
| What shape is a dacryocyte? |
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Definition
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Term
| What abnormal red cell could result from forceful extrusion or removal of the nucleus in extramedullary hematopoiesis? |
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Definition
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Term
| Removal of rigid inclusion bodies such as hemosiderin, Howell Jolly bodies or Heinz bodies by reticuloendothelial cells can result in this cell type. |
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Definition
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Term
| What shape is a codocyte when it's in the body? |
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Definition
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Term
| What does a codocyte look like on the blood smear? |
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Definition
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Term
| Increased cholesterol and phospholipid in red cell membrane causes increased surface area resulting in what abnormal cell? |
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Definition
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Term
| What diseases are associated with codocytes? |
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Definition
| obstructive liver disease, hemoglobinopathies (S and C), thalassemia, iron deficiency, postsplenectomy. |
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Term
| What is the name for a scell that is shaped like a cup, that looks like a mouth on the blood smear? |
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Definition
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Term
| Increase in the inner lipid bilayer in relation to the outer lipid bilayer results in what abnormal cell shape? |
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Definition
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Term
| A cell of normal or slightly reduced size with 3 to 12 blunt spicules of uneven length distributed along the periphery of the cell membrane? |
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Definition
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Term
| How can you tell between an acanthocyte and echinocyte? |
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Definition
| Acanthocyte has 3 to 12 spicules; echinocyte has 10 to 30 spicules |
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Term
| This abnormal cell is caused by an increase in cholesterol, increased surface area and decreased lecithin in the cell membrane. |
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Definition
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Term
| Cells that have an essentially normal cell volume, but demonstrate one or more projections or horns. |
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Definition
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Term
| What abnormal red cell morphology is associated with mechanical trauma and impact hemolysis, DIC and pulmonary emboli? |
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Definition
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Term
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Definition
| cell fragments which are irregular in shape and size. |
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Term
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Definition
| abnormalities in hemoglobin synthesis |
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Term
| if a red cell has a central pallor of greater than 3 u, what is this called? |
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Definition
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Term
| What illnesses can cause hypochromia? |
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Definition
| iron deficiency anemia, thalassemia, sideroblastic anemia and lead poisoning |
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Term
| If you see polychromasia, what are you actually seeing? |
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Definition
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Term
| What cells look gray-blue on a wright-stained smear and are also usually larger than normal? |
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Definition
| polychromatophilic rbc's/reticulocytes |
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Term
| If you saw hemoglobin C crystals in the blood smear, what would you do next? |
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Definition
| hemoglobin electrophoresis |
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Term
| Are Howell Jolly bodies visible on the wright stained smear? |
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Definition
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Term
| Is it possible for a nucleated RBC to have Howell Jolly bodies? |
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Definition
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Term
| What are Howell Jolly bodies composed of? |
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Definition
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Term
| Is it normal to see a couple of Howell Jolly bodies here and there? |
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Definition
| No. It's always abnormal to see them. |
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Term
| What is basophilic stippling made out of? |
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Definition
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Term
| What inclusions would you see in lead poisoning? |
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Definition
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Term
| what are Pappenheimer bodies made out of? |
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Definition
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Term
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Definition
| A cell with pappenheimer bodies |
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Term
| Are heinz bodies visible on the wright stained smear? |
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Definition
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Term
| What stain would you use if you wanted to check for heinz bodies? |
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Definition
| supra-vital stain like crystal violet or brilliant cresyl blue |
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Term
| what are heinz bodies made out of? |
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Definition
| denatured or precipitated hemoglobin |
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Term
| what inclusion is thought to be remnants of the mitotic spindle? |
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Definition
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