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Definition
CASE: 14y/o girl with bilateral knee pain and swelling for 2 weeks, symptoms improved, then 1 week ago right knee started to hurt.
She had a soar throat, fever one month ago. |
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Definition
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ACQUIRED heart disease : 90,000 ppl die annually
Mortality 1-10% |
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Definition
| RHD is the leading cause of what world wide? |
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Term
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Definition
| RF develops how long after sore throat. |
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Direct contact
Respiratory secretions
Crowded living conditions
Genetic predisposition/HLA markers |
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Definition
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Definition
| RF can develop after infection with Group A beta-hemolytic strep of what organ? |
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| GAS produce several toxic enzymes that have effects on heart tissue |
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Definition
| Cytotoxic theory of pathogenesis of RF |
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| Rheumatogenic strains are stronly immunogenic and ABs against strep and may cross react with heart tissue |
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Definition
| Immune Mediated theory of RF |
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Term
J-joints for polyarthritis (MOST COMMON) Low to High
O- Heart (2nd Most common)
N- Subcutaneous nodules (extensor surface)
E-Erythema Marginatum
S- Sydenham Chorea (purposeless movements of arms) |
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Definition
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Endocarditis murmur insufficiency (M>A>T>P valves)
also: pericarditis, myocarditis, pericarditis, tachycardia
Stenosis occurs 2-20 years after complications |
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Definition
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Definition
| All problems except _________ will resolve? |
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Arthralgia
FV
Elevated ESR, CRP
Prolonged PR period |
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Definition
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Term
2 major OR 1 major + 2 minor
And must have evidence of GAS infection |
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Definition
| Dx requires how many of each criteria? |
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Term
throat culture
rapid antigen test
Elevated blood tests: ASO (prior infx), Anti-DNAse B, Anti-hylauronidase titer |
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Definition
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Term
Mitral Valve Stenosis
Cardiomegaly
CHF
Hepatosplenomegaly
Pulmonary Edema
Increased risk of infective endocarditis |
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Definition
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Term
Antibiotic: oral PCM, IM Benthazine PCN
Aspirin
Steroids for inflammation
Bed rest |
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Definition
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Term
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Definition
| Must treat strep phayringitis within ______days of symptom onset to prevent RF |
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| IM Benzathine PCN G every 3-4 weeks |
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Definition
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