Shared Flashcard Set

Details

859-III
Cytotec for Postpartum Hemorrhage
9
Medical
Graduate
02/05/2012

Additional Medical Flashcards

 


 

Cards

Term
What is misoprostol?
Definition
Prostaglandin E1 analogue
Term

Misoprostol

mechanism of action

Definition

Produces uterine contractions

 

Decreases gastric acid secretion

Term
Misoprostol Indications
Definition

1. Cervical ripening for induction of labor

2. Medical abortion with mifepristone

3. Prevention of gastric ulcers secondary to NSAID use

4. Treatment of duodenal ulcers (off-label)

5. Treatment of acute PPH (off-label)

Term
Contraindications to misoprostol use
Definition

1. Hypersensitivity

2. Do not use during pregnancy for GI indications

3. Cervical ripening with prior c-section or other uterine surgery

4. Caution in pt. with CV disease or IBD

Term

Misoprostol 

dosage and route

Definition

PO, rectally, sublingually, vaginally, or IM

 

Dosage range 400 to 1000 mcg

Term
Misoprostol side effects
Definition

Diarrhea

Abdominal pain

Fever/chills

Nausea/vomiting

Tachycardia

Headache

Term
Advantages of misoprostol
Definition

1. Very cost-effective

2. No significant contraindications

3. Fewer side effects than Hemabate

4. Not contraindicated in pt. with hypertension

Term

ACOG Recommended

dosage of misoprostol

Definition

*1st choice is always oxytocin

 

800 - 1000 mcg per rectum once

Term

Recommended sublingual and oral doses 

of misoprostol

Definition

400 to 600 mcg PO

 

or

 

400 to 600 mcg sublingual

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