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7-Barrett's Esophageus
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21
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Kindergarten
11/14/2012

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Cards

Term
Squamous to columnar
Definition
What is the epithelium change in Barret's Esophagus
Term
GERD----->Barret's Esophageus
Definition
Case Study: 55 year old man comes in complaining of burning in the chest. Pain radiates to his neck. Sometimes awakes him from his sleep. Difficulty swallowing solid foods. Symptoms are getting worse over several years. What do they have?
Term
Distal Esophagus
Definition
Where is Barretts esophagus found?
Term
Adenocarcinoma
Definition
What is the cancer associated with Barretts
Term
Low (5 year is 15-20%)
Definition
Survival rate of Barretts?
Term
Advanced age
Male
White
Reflux issues
Obesity
Definition
Risk factors of Barrets (5)
Term
Heart Burn
Definition
retrosternal burning, usually regurgitation of gastic contents into LES:
Term
GERD
Definition
Decreased efficacy of esophageal anti-reflux mechanism, particularly of LES tone
Term
LES tone problem
Sliding Hiatal Hernia
Slowed clearance of reflexed material
Delayed gastric emptying
Reduction of repair capacity of mucosa
Definition
5 causes of GERD?
Term
Barretts with no symptoms - yearly

Barretts with ALARM symptoms - EVERY six months
Definition
When to Endoscope in Barretts?
Term
Dysphage odonyophagia
weight loss
early satiety
anemia
new onset
Male >45
Definition
ALARM symptoms of Barretts (6)
Term
Four quadrant biopsy; specimens obtained every 2cm along the extent of the esophagus
Definition
How to biopsy Barretts
Term
Single erosion above esophageal jxn
Definition
Grade 1 barretts
Term
Multiple, non circumferential erosions above esophageal jxn
Definition
Grade 2 barretts
Term
Circumferential erosion covered by hemorrhagic and pseudomembranous exudate
Definition
Grade 3 barretts
Term
chronic change with esophageal ulceration and associated structure barretts metaplasia
Definition
Grade 4 barretts
Term
Barretts esophagus with histologically confirmed intestinal differentiation with columnar epithelium
Definition
Grade 5 barretts
Term
1. histological evidence of interstinal metaplasia

2. Columnar epithelial lines above GEJ
Definition
What two criteria are needed to diagnose barretts
Term
1st: PPI

2nd: Surgery
Definition
Tx of barretts
Term
Hoarsness, aspiration pneumonia, non cardiac chest pain, bleeding
Definition
extaesophageal symptoms of GERD
Term
Anemia
Weight loss
worsening dysphagia
GI bleed
Persistent vomiting
Palpable mass
Definition
Endoscopy indications? (6)
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