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6-Asbestosis
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33
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Pre-School
11/13/2012

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Term
Asbestosis
Definition
Shipyard worker for 18 years, has dyspnea and non-productive cough.

CXR- Calcified lesions on diaphragm

Physical: Bilateral basilar crackles

What do they have?
Term
Pneumoconiosis
Definition
Occupational lung disease caused by inhalation of dust.
Term
Asbestos
Coal Workers Disease
Silicosis
Definition
3 examples of Pneumoconiosis
Term
occur as fibers, either straight (most dangerous due to being easier to deposit) or curved
Definition
Describe Asbestos particles:
Term
when they are airborn and inhaled due to renovations. Disease is associated with long-term exposure.
Definition
When are asbestos particles most dangerous?
Term
SHIP AND BOAT BUILDERS
Mining, construction, plumbing
Electricians, Insulation, breakline
NAVY
Definition
Which individuals should be screened for asbestos?
Term
Pulmonary Function Tests
CXR:
3-5 years for <10 year exposure
1-2 years for > 10 year exposure
ANNUAL FOR >20 YEAR EXPOSURE
Definition
How are individuals screened for Asbestos? (2) And when should they be tested?
Term
Affects lung function and increases risk of pneumothorax due to thickening of pleura. NOT CANCEROUS
Definition
When happens when the pleura is affected by asbestos?
Term
5-20 years after chronic exposure
Definition
How long does it take asbestosis to occur?
Term
DECREASES DLCO (diffusion capacity)
Definition
Asbestos inflammation causes scarring and stiffening of the lung which (increases or decreases) DLCO?
Term
Dyspnea
Nonproductive cough
clubbing and cyanosis-late signs
chest pain-not common
Definition
Major Symptoms of Asbestosis?
Term
Bilateral basal reticulonodular infiltrates
Shaggy Heart ground glass appearance
Definition
CXR findings?
Term
Pleural Plaques
Basilar interstitial Fibrosis (scarring)
Fine and coarse honeycombing
rounded atelectasis
pleural adhesions
Definition
HCRT findings?
Term
Usually restrictive pattern
Decreased TLC and DLCO
Definition
Pulmonary function test findings?
Term
Rarely, but only if accelerated clinical course and you will find asbestos bodies
Definition
When does a patient need a biopsy with asbestosis and what are the findings?
Term
Tachycardia, and right heart failure
Definition
Cardiac Exam findings?
Term
NO SMOKING
O2
pulmonary rehab
resection of bronchogenic carcinoma
Definition
Non pharm tx of asbestos
Term
No drugs really work. Control other conditions such as COPD.
Definition
pharm management of asbestos
Term
cigarettes
Definition
Synergy between asbestos and _____exposure causes 59x more risk of cancer
Term
Mesothelioma
Definition
Cancer of the lining of the lung and chest cavity due to asbestos?
Term
Pleural 2/3
Definition
Is Mesothelioma found in the pleural or peritoneal more often?
Term
30-50 years to develop
Rapidly fatal 75% after 1 year.
Smoking does not increase risk
Definition
How long does it take mesothelioma to develop and what is the prognosis?
Term
smoking
environmenta/occupational exposure
CT diseases
Definition
What are some other risk factors for common interstitial lung diesease?
Term
Progressive Dyspnea on exertion and non-productive cough
Hemoptysis or fatigue
Clubbing/cyanosis
Inspiratory squeks
If you suspect a systemic disease:
ACE: sarciodosis
CANCA: wegners
PANCA: churg strauss
Antiglomerular basement membrane antibody: GoodPasture
Serum Precipitating AB: Hypersensitivity Pneumonitis
Definition
What are the physical exam findings associated with interstitial lung diseases?
Term
Silicosis
Definition
Most common pneumocosis in USA
Term
Sarcoidosis
Definition
36 y/o African american female complaining of exertional dyspnea, dry and non productive cough
Term
Beryilliosis
Definition
Ceramic workers get this:
Term
Radiology: Bilateral symmetric hilar adenopathy of upper lung zone reticular opacities

Physical: Raynaud's

Lab: elevated ACE and hypercalcemia
Definition
Findings of Sarcoidosis:
Term
Dermatomyositis
Definition
Heliotrope rash with Gottron's Sign: what condition?
Term
Neurofibromatosis
Definition
Cafe la spots found in what condition?
Term
Wegners
Definition
cANCA postive, Radiology shows ill defined nodule with an air bronchogram due to hemorrhage and necrosis
Term
Churg Strauss
Definition
Patient has nasal polyps and asthma
pANCA positive
Term
Goodpasture's Syndrome
Definition
Patient has a history of pulmonary and urinary complaints and Labs show antiglomerular basement membrane antibody
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