Term
STEMI --> Anticoagulation is administered (Streptokinase)
What is the most common SE of streptokinase administration? |
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Definition
Hemorrhage
(ASIDE: streptokinase is a bacterial product, thus has the potential to cause hypersensitivity reactions, just like many antibiotics, notably penicillins) |
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Term
Triad of pre-eclampsia?
Eclampsia?
HELLP syndrome? |
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Definition
- HTN, Proteinuria, Edema
- Pre-eclampsia + seizures
- Hemolysis, Elevated liver enzymes, Low platelets (may develop from pre-eclampsia |
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Term
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Definition
| inability to be still. Common SE of antipsychotics |
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Term
IL causeing IgE class switching?
IgA? |
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Definition
IL4
IL5 (IL5 is also chemotactic & pro-growth for eosinophils) |
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Term
Deletion of this gene protects against HIV?
What is the function of nef gene? |
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Definition
CCR5
nef downregulates MHC-I receptors |
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Term
| parotid gland is innervated by what nerve? |
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Definition
| IX (through otic ganglion --> auriculotemporal branch of CN-V2) |
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Term
wide fixed S2
can this lead to eisenmenger syndrome? |
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Definition
ASD
Yes, if the defect is hemodynamically significant (remember that ASDs are the most common congenital heart defect, present in as high as 30% of the population) |
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Term
Treatment for high cholesterol is begun. W/in 3mo of initiation, person comes in with decreased appetite & malaise.
What was the drug?
What is it's side effect that is causing the sx? |
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Definition
Statins
Hepatotoxicity (get liver enzymes to confirm)
NOTE: fibrates also cause hepatotoxicity.
Statins also cause myopathy |
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Term
| G+, rod-shaped bacteria with subterminal spore |
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Definition
| Clostridium (an anaerobe) |
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Term
| name signal transduction for alpha1 receptors |
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Definition
GPCR --> phospholipaseC --> IP3 & DAG released
IP3 --> increase Ca release from ER/SR --> Ca activates PKC
DAG --> directly activates PKC |
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Term
Crampy abdominal colic, constipation, discoloration between teeth & gingivae, neurologic signs
Basophilic stippling on peripheral smear |
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Definition
Lead poisoning
Kids eating paint chips, adults w/ occupational exposer (e.g. battery manufacturing, industrial workers) |
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Term
| What part of the peptidoglycan amino-acid sequence is cross-linked? |
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Definition
D-ala D-ala
the NH2 group from adjacent L-lys group attaches to D-ala group |
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Term
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Definition
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Term
| Tx for TCA-induced cardiac arrhythmias (QRS & QT prolongations) |
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Definition
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Term
| treatment for suspected aspirational pneumonia (alcoholic w/ poor dentition & foul-smelling sputum) |
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Definition
Clindamycin (covers anaerobes)
oral flora causing anaerobic pneumonia: bacteroides, prevotella, fusobacterium, peptostreptococcus |
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Term
| 2 antiepileptics that are "mood-stabilizers", and thus can be used for bipolar |
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Definition
| Valproic acid & carbamazepine |
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Term
| morphology of mucor/rhizopus |
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Definition
broad, non-septate hyphae that branch @ right angles & have sporangium
remember: diabetic patient w/ paranasal infection & black discharge |
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Term
| Neutropenic patient (esp leukemic pt) w/ signs of extrapulmonary involvement (e.g. sinus) of a fungus branching @ 45 degree angles |
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Definition
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Term
Haloperidol, Fluphenizine, Pimozine, Chlorpromazine, Thioridazine
Which ones are high & which ones are low potency? |
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Definition
High: Haloperidol, Fluphenazine, Pimozine
Low: Chlorpromazine, Thioridazine
NOTE: atypicals include Clozapine, Risperidone, Olanzapine, Quetiapine (fewer 'negative' symptoms) |
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Term
Which DNA polymerase removes RNA primers in Okazaki fragments (via 5'->3' exonuclease activity)?
Which DNA pol carries out normal replication? |
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Definition
- DNA pol I removes RNA fragments & lays down DNA
- DNA pol III is responsible for majority of DNA synthesis during replication |
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Term
| Where is wernickes area located? What artery supplies it? |
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Definition
| Posterosuperior temporal lobe. Middle cerebral (also supplies Broca's area in the inferior frontal gyrus of the frontal lobe) |
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Term
Atopic dermatitis (or eczema in general) is associated w/ other atopic diseases. name 2?
Hint:
one is in the nose
one is in the lungs |
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Definition
Allergic rhinitis (chronic will give you polyps)
Asthma
all of these things are typeI hypersensitivity reactions |
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Term
| Alcohol, Barbiturates & hypoxia will cause an increase in what step of heme synthesis? |
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Definition
| ALA synthase (takes place in mitochondria) |
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Term
| Peripheral lung tumor: columnar cells joined by desmosomes w/ abundant tonofilaments and studded, long microvilli |
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Definition
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Term
| Elevated AlkPhos & antimitochondrial antibodies |
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Definition
Primary biliary cirrhosis
granulomatous intrahepatic bile-duct destruction & heavy lymphocyte-predominant portal tract infiltrate (looks very similar to graft-vs-host disease) |
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Term
| If a male has cryptorchidism. What part of the hypothalamic->pituitary->testes signaling access is downregulated? |
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Definition
inhibin
seminiferous tubules are obliterated, and sertoli cells are not present to secrete inhibit. In contrast, testosterone-secreting Leydig cells are not temperature sensitive and have no problems |
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Term
| 2 Growth factors that promote angiogenesis (e.g. in granulation tissue) |
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Definition
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