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4.13 Emergency Lab Medicine
By Dr. McGoey
71
Pathology
Professional
04/14/2012

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Cards

Term
What are the 3 categories of the glasgow coma scale?
Definition
eye opening, verbal response, motor response
Term
What are the possible scores you can get for eye opening on the glasgow coma scale?
Definition
4= spontaneously, 3= to speech, 2= to pain, 1= none
Term
What are the verbal response scores on the glasgow coma scale?
Definition
5= oriented, 4= confused, 3=inappropriate, 2= incomprehensible, 1= none
Term
What are the motor response scores on the glasgow coma scale?
Definition
6=obeys commands, 5=localizes to pain, 4= withdraws from pain, 3=flexion to pain, 2= extension to pain, 1= none
Term
What is the maximum glasgow coma scale score?
Definition
15
Term
What are the ABCDEs?
Definition
airway, breathing, circulation, disability, exposure
Term
At what point is a breathing rate too slow? too fast?
Definition
<8= too slow; >40=too fast
Term
How do you asses for disability?
Definition
AVPU (alert, responds to verbal stimuli, responds to painful stimuli, unresponsive)
Term
What does SAMPLE stand for?
Definition
signs/symptoms, allergies, medications, PMH, Last oral intake, events leading to current problem
Term
What does ROLAIDS stand for?
Definition
radiation, onset, lasting how long, aggravators/relief factors, degree or severity, spreads anywhere (radiation)
Term
Name some causes of changes in mental status?
Definition
toxicity, infection, porphyria/pharmaceuticals, space occupying lesions, seizures, shock, sepsis
Term
What types of things can cause long QT syndrome?
Definition
electrolyte abnormalities, hereditary LQTS, drugs (antiarrhythmics, tricyclics, phenothiazines)
Term
What kinds of electrolyte abnormalities cause long QT syndrome?
Definition
decreased K+, decreased Ca, decreased Mg
Term
How many cases of TCA overdose are there per year?
Definition
>6000
Term
What is the mortality rate of TCA overdose?
Definition
1-2%
Term
What are the symptoms of TCA overdose?
Definition
anti-cholinergic actions: mental status change, febrile, erythema, mydriasis, dry
Term
What does PCP stand for?
Definition
phecyclidine
Term
What are the commonly screen toxicologies?
Definition
cocaine, morphine, benzodiazepines, barbiturates, amphetamines, PCP, methadone, THC, heroin, ethanol, codeine
Term
What are the two most common toxicities?
Definition
#1= tylenol; #2= alcohol
Term
What types of substances count as "alcohol"?
Definition
ethanol, isopropyl alcohol, methanol, ethylene glycol
Term
What BAC is considered legally drunk?
Definition
.08% or 80mg/dL
Term
What BAC is lethal?
Definition
>.5% or 500mg/dL
Term
At what BAC do you experience coma?
Definition
0.3% or 300 mg/dL
Term
At what BAC do you experience respiratory depression?
Definition
0.4% or 400 mg/dL
Term
At what BAC do you experience lethargy, stupor, and vomiting?
Definition
.2% or 200 mg/dL
Term
At what BAC do you experience ataxia and slurred speech?
Definition
.1% or 100 mg/dL
Term
Is AST sensitive or specific for liver disease?
Definition
sensitive
Term
Is ALT sensitive or specific for liver diesease?
Definition
specific
Term
What is the AST and ALT in patients with EtOH related liver disease?
Definition
both are elevated but not above 500. AST:ALT ratio= >2.5
Term
Is PT an early or late marker of liver failure?
Definition
early
Term
What kind of liver disease causes decreased albumin?
Definition
advanced, end-stage liver disease
Term
Name the viruses that can cause hepatitis?
Definition
hep A, B, C, D, E, herpes simplex, cytomegalovirus, epstein-barr, adenovirus
Term
What are the three most common types of acute viral hepatitis in the US?
Definition
HAV>HBV>HCV
Term
What is the first marker to rise in HBV?
Definition
HBsAg
Term
What is the window period?
Definition
time between the antigen's disappearance and the antibody's appearance
Term
What is the second marker to rise in HBV?
Definition
Anti-HBc
Term
What indicates a patient with HBV is no longer infective?
Definition
anti-HBe
Term
T/F Anti-HBs rises only after HBsAg is gone.
Definition
true
Term
How long does it take for anti-HBcIgM to disappear?
Definition
6 months
Term
What is the AST and ALT level in viral hepatitis?
Definition
500-4000
Term
Periumbilical ecchymosis=
Definition
cullen's sign
Term
Flank ecchymosis=
Definition
Grey-Turner sign
Term
How long do the symptoms of acute pancreatitis last?
Definition
one week
Term
What are the Ranson criteria for prognosis on admission?
Definition
glucose >200, age >55y, LDH >350, AST >250, WBC >16
Term
What are the Ranson criteria for prognosis at 48 hours?
Definition
calcium less than 8, Hct drops by 10%, paO2 <60, BUN drops by 8, sequestration of >6L fluid
Term
What does a ranson score of 3-5 mean?
Definition
10-30% mortality
Term
What does a ranson score of more than 5 mean?
Definition
50% mortality
Term
What does a ranson score of more than 8 mean?
Definition
100% mortality
Term
Is amylase sensitive or specific for pancreatitis?
Definition
sensitive>specific (both rather low but specificity improves with amylase P
Term
How long does it take amylase to return to normal?
Definition
2-5 days
Term
Is LDH specific or sensitive for pancreatitis?
Definition
sensitive>specific (specificity improves with LDH-4)
Term
Is Lipase more sensitive or specific?
Definition
specific>sensitive
Term
How long does lipase stay elevated for pancreatitis?
Definition
7-10 days
Term
What is Murphy's sign?
Definition
severe RUQ pain to palpation (winces and becomes breathless)
Term
Abdominal pain first followed by N/V indicates...
Definition
a surgical problem
Term
N/V first followed by abdominal pain indicates..
Definition
a medical problem
Term
Murphy's signs suggests what disease?
Definition
cholecystitis
Term
What's the difference between cholecystitis and cholangitis?
Definition
cholecystitis is GB inflammation usually with stone in cystic duct and cholangitis is due to infection (usually e.coli)
Term
What's charcot's triad?
Definition
fever, RUQ pain, and jaundice
Term
What is Reynold pentad?
Definition
charcot + mental status change + hypotension; suggests cholangitis
Term
Is ALP sensitive or specific for biliary disease?
Definition
sensitive>specific (also present in bone, liver, intestine, placenta)
Term
What are findings on CT suggestive of appendicitis?
Definition
thickened appendix with "target sign," enlargment and accumulation of periappendiceal exudate suggests perforation
Term
What is the most common surgical emergency?
Definition
acute appendicitis
Term
What is the incidence of acute appendicitis?
Definition
7%
Term
What is the typical age range of acute appendicitis?
Definition
80% are less than 40 yoa but 20% are adults
Term
What is the classical presentation of acute appendicitis?
Definition
periumbilical first then RLQ pain (McBurney point), anorexia, fever, N/V
Term
What causes malposition of appendix?
Definition
intestinal malrotation shifts it to LUQ, pregnancy shifts it to RUQ
Term
What are the complications of acute appendicitis?
Definition
perforation (first 24 to 36 hours)
Term
What are the WBC findings in appendicitis?
Definition
mildly elevated in 85% (range 10-16); neutrophilia (75%) on the differential
Term
What are the findings on urinalysis for appendicitis?
Definition
50% have RBCs and WBCs
Term
What test for appendicitis has a high negative predictive value?
Definition
CRP
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