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3802
Pain Unit
43
Biology
Undergraduate 1
03/21/2009

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Term
Definitions of Pain
Definition
"Unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage"

"Pain is whatever the experiencing person says it is existing whenever the experiencing person says it does"

Term
Pain Threshold
Definition
Point at which a stimulus evokes pain
Term
Pain tolerance
Definition
duration or intensity of pain a person is willing to endure
Term
Tolerance to opioids
Definition
after repeated administration of the medication, a given dose begins to lose its effectiveness
Term
Dependency
Definition
Involuntary behavior in which abrupt discontinuance of a drug leads to withdrawal symptoms.
Term
Addiction
Definition
A primary, chronic, neurobiologic disease, with genetic, psychosocial, and environmental factors influencing its development and manifestations. It is characterized by behaviors that include one or more of the following: impaired control over medication use, compulsive use, continued use despite harm, and craving
Term
Acute Pain
Definition
Usually temporary, well-defined onset - serves as a warning signal, commonly declines over a short time, < 3 months or as long as it takes for normal healing to occur

Physiological responses - stress response

Behavioral responses - Focuses on pain, cries and moans, frowns, grimaces

Term
Chronic/Persistent Pain
Definition
Usually greater than 6 months in duration - may start as acute injury or event but continues past the normal recovery time poorly defined onset, no useful purpose

Physiological responses – Adaptation

Behavioral responses - No report of pain unless questioned, quiet, rests, inactive, immobile, blank or normal facial expression; can be disabling and is often accompanied by anxiety and depression

Term
Nociceptive Pain
Definition
Normal processing of stimuli that damages normal tissue or has the potential to do so if prolonged

Usually responsive to nonopioids and/or opioids

Types of nociceptive pain: somatic pain and visceral pain

Term
Somatic Pain
Definition
Arises from bone, joint, muscle, skin or connective tissue

Usually aching or throbbing in quality and is well localized

Term
Visceral Pain
Definition
Arises from viscera, such as the GI tract and pancreas

May be due to tumor involvement of the organ capsule that causes aching and fairly well-localized pain

May be due to obstruction of hollow viscus, which causes intermittent cramping and poorly localized pain

Term
Neuropathic Pain
Definition
Abnormal processing of sensory input by the peripheral or central nervous system

Treatment usually includes adjuvant drugs

A physical cause for reports of excruciating pain may not be evident on examination

Term
Examples Neuropathic Pain:
Definition
Phantom limb pain – may reflect injury to the peripheral nervous system

Diabetic neuropathy

Term
Harmful Effects of Unrelieved Pain (Table 10-1, page 126)
Definition
Unnecessary suffering

Physical and psychosocial dysfunction

Impaired recovery from acute illness and surgery

Immunosuppression

Sleep disturbances

Term
Theories Related to Pain
Definition
Specificity Theory – hypothesis that pain is related to specific anatomic structures and physiologic functions

Pattern Theory – accounted for abnormal pain states not explained by specificity theory  Specificity Theory – hypothesis that pain is related to specific anatomic structures and physiologic functions

Pattern Theory – accounted for abnormal pain states not explained by specificity theory

Term
Theories Related to Pain (cont.)
Definition
Psychosocial Theory – views pain as an emotion or as the manifestation of an emotional state

Gate Control Theory - hypothetical gating mechanism in the spinal cord that allows nerve fibers to receive pain sensations.

Term
Pain Assessment
Definition
Location

Quality

Intensity

Onset/Duration

Precipitating, relieving and aggravating factors

Term
Location
Definition
Ask the patient to mark the location(s) on a figure drawing

Ask the patient to point on his or her body the location of pain(s)

Does it radiate to any other part of his body?

Term
Quality
Definition
"What is the pain like?"

"Can you describe how it feels?"

“What would you do to me for me to feel the same pain?”

Term
Intensity
Definition
Ask the patient to rate it on a scale of 0 to 10 (with 10 being the worst pain).

An intensity rating scale can also be used to evaluate therapy.

Term
Set Goals for Comfort and Function/Recovery
Definition
Pain ratings of 4 or greater interfere with a patient’s activity

Pain ratings of 6 and 7 interfere with enjoyment of life

Term
Duration
Definition
"How long does the pain last?"

Constant or intermittent (come and go)?

Term
Precipitating and Aggravating Factors
Definition
What, if anything, brought on the pain?

"Is there anything that makes the pain worse?".

Term
Pain Assessment
Definition
Approximately half the people who suffer moderate to severe pain will continue to suffer primarily because clinicians fail to assess pain.
Term
Pharmacological Measures: Nursing Responsibilities
Definition
Assessing pain

Determining when to administer analgesics

Selecting the appropriate analgesic (titrating opioids)

Evaluating effectiveness of the analgesics

Term
Pharmacological Measures: Nursing Responsibilities
Definition
Monitoring and managing medication side effects

Suggesting changes

Consider the needs of special populations (cognitively impaired, patients with substance abuse problems)

Term
Patients with Impaired Communication
Definition
They have pain too
Term
Cognitively Impaired Elders
Definition
Even patients with substantial cognitive impairment may be able to use a pain rating scale.

Allow sufficient time for the patient to process the information and then respond.

Usually a 0 to 5 scale is preferable to a 0 to 10 scale for these patients.

Term
Nonopioids
Definition
Acetaminophen

NSAIDs

Aspirin

Ibuprofen

Ketorolac

Naproxen

Term
Indications
Definition
Inflammatory conditions

Mild to moderate acute or chronic pain of peripheral origin

Co-analgesic for severe pain

Desire by patient to avoid opioids

Conditions associated with excessive prostaglandin at site of injury or pain

Postoperative pain

Term
Disadvantages
Definition
Analgesic ceiling

Gastrointestinal upset

Prolonged bleeding time

Fluid retention

Term
Opioid Agonists
Definition
Codeine

Meperidine

Hydrocodone

Methadone

Hydromorphone

Morphine

Oxycodone

Term
Demerol-toxicity
Definition
Not appropriate for first-line opioid for management of any type of pain (AHCPR 1992)

Active metabolite (normeperidine)

Normeperidine is a CNS stimulant – can produce irritability, tremors, muscle jerking, agitation, and seizure

Normeperidine – half-life of 15-20 hours

More likely to cause delirium in postoperative patients of all ages

Term
Opioid Agonist-Antagonist
Definition
Buprenorphine (Buprenex)

Butorphanol (Stadol)

Nalbuphine (Nubain)

Pentazocine (Talwin)

Dezocine (Dalgan)

Term
Dosing
Definition
ATC – indicated when pain is predicted to be present for 12 or more hours out of 24 hours

PRN – requires patients to request analgesia, appropriate for intermittent pain

Term
Equianalgesic Tables
Definition
Use published tables when converting to another drug or another route
Term
Disadvantages of Opioids
Definition
Sedation

Nausea and vomiting

Respiratory depression

Constipation

Term
"Potentiators"
Definition
Promethazine (Phenergan) does not potentiate the analgesia of narcotics. It actually increases the perceived intensity of pain. Phenergan does potentiate narcotic-related sedation, hypotension, and respiratory depression.
Term
Adjuvant Drugs
Definition
Antidepressants
Antiseizure agents
Corticosteroids
Local anesthetics
Term
Routes of Administration
Definition
Oral

Intramuscular

Intravenous

Rectal

Sublingual/buccal

Subcutaneous

Spinal

Topical

Transdermal

Intranasal

Term
Non-Invasive Non-Pharmacological Methods of Pain Relief
Definition
Repositioning

Heat

Cold

TENS

Acupressure

Massage

Therapeutic touch

Term
Invasive Interventions
Definition
Acupuncture

Neuroaugmentation

Nerve blocks

Term
Specificity Theory
Definition
– hypothesis that pain is related to specific anatomic structures and physiologic functions
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