Term
| what is another name for grand mal seizures? |
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Definition
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Term
| Describe absence seizures |
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Definition
| petit mal; when you stare into space |
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Term
| Describe status epileptucis |
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Definition
| prolonged seizure, series of repeated seizures that does not resolve on its own |
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Term
| What are some common actions of seizure drugs? |
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Definition
| makes patient groggy, sleepy with dry mouth |
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Term
| Describe the use of anti seizure drugs |
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Definition
| started one at a time, drug can be increased or changed if not effective; choice of drug depends on seizure type |
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Term
| What is the purpose of first line seizure drugs? |
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Definition
| decrease voltage frequency and spread of electrical impulses in motor cortex of the brain |
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Term
| Patients taking carbamazepine should avoid what? |
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Definition
| grapefruit and grapefruit juice. |
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Term
| Valproic acid during pregnancy has been associated with what side efects? |
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Definition
| developmental defects, low IQ, birth defects, congenital anomalies, and damage to the infant’s liver. |
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Term
| What first line drug for absence seizures can make you sensitive to light? |
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Definition
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Term
| What is the function of second line seizure drugs? |
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Definition
| increase threshold to stimuli, slowing electrical impulses, stabilize membranes of neurons |
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Term
| Gabapentin should not be given with what? why? |
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Definition
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Term
| What are the 3 forms of depressive disorder? |
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Definition
| major depression, dysthymia, bipolar disorder |
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Term
| What is the cause of psychiatric disorders? |
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Definition
| imbalance of neurotransmitters; serotonin, dopamine, and norepi |
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Term
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Definition
| less severe chronic form of depression; persistently low moods |
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Term
| What are the 3 types of antidepressant drugs? |
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Definition
| Selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs) |
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Term
| What are the general side effects of antidepressants? Adverse effects? |
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Definition
| hypotension, headache, dry eye dizziness, drowsiness; TCAs- cardiac, NDRIs- seizures, suicidal thoughts |
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Term
| Depression may be caused by the depletion of ____ |
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Definition
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Term
| TCAs inhibit the reuptake of what? |
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Definition
| serotonin, dopamine, norepi |
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Term
| How long does it take for antidepressants to work? |
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Definition
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Term
| Antidepressant drugs should not be used for ____ days after discontinuing _____ for risk of _______ |
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Definition
| 14 day; MAOI drugs; serotonin syndrome |
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Term
| Beta blockers also function as ___ |
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Definition
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Term
| What are two categories of antianxiety drugs? |
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Definition
| benzodiazapines (CNS depressant) and SSRIs |
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Term
| What are two other terms for antianxiety meds? |
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Definition
| anxiolytics or minor tranquilizers |
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Term
| Benzos should not be taken with ___ |
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Definition
| antacid; decreases absorption; avoid grapefruit juice |
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Term
| Why should benzos be avoided in pregnancy? |
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Definition
| fetus can becooe dependent and cause withdrawal symptoms after birth |
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Term
| Chlordiazepoxide and clorazepate (Tranxene) are not recommended for older adults why? |
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Definition
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Term
| How do antipsychotic drugs work? |
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Definition
| relax CNS, block dopamine receptors in the brain |
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Term
| Taking antipsychotics clozapine or prochlorperazine can cause ____ |
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Definition
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Term
| The antipsychotic Clozapine can cause ____ |
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Definition
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Term
| Antipsychotics Quetiapine, risperidone, and ziprasidone should not be given to adults why? |
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Definition
| increases COD with dementia |
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Term
| What are the symptoms of parkinson's disease? |
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Definition
| tremor at rest, rigidity, bradykinesia, abnormal gait |
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Term
| How do drugs for parkinson's work? |
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Definition
| increase dopamine activity in the brain |
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Term
| What is the function of COMT inhibitors? |
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Definition
| allow more levodopa to reach brain |
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Term
| What is the function of MAO-B inhibitors? |
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Definition
| inhibit monamine oxidase B that breaks down dopamine in brain |
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Term
| Apomorphine for parkinson's can cause what? |
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Definition
| life threatening CNS depression |
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Term
| Bromocriptine stops the production of what? |
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Definition
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Term
| What is the most common type of glaucoma? |
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Definition
| primary open angle, affects both eyes, chronic |
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Term
| eye meds can also go where? |
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Definition
| in the ear but not vice versa |
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Term
| What are the 5 types of drugs that treat glaucoma? |
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Definition
| prostaglandin agonists, beta blockers, adrenergic agonists, cholinergic, carbonic anhydrase inhibitors |
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Term
| Describe the purpose of prostaglandin agonists to treat glaucoma |
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Definition
| Bind to prostaglandin receptor sites, relax blood vessels;cause blood vessels to dilate, collect more fluid |
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Term
| Describe the use of beta blockers to treat glaucoma |
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Definition
| Block beta-adrenergic receptors, prevent adrenalin from binding to them |
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Term
| Describe the use of carbonic anhydrase inhibiors to treat glaucoma |
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Definition
| reduce production of aqueous humor to lower IOP |
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Term
| What is the purpose of glaucoma drugs? |
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Definition
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Term
| What are the systemic effects of beta adrenergic blocking agents for glaucoma? |
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Definition
| slow HR and can lead to HF; narrow airways; can mask signs of hypoglycemia |
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Term
| Adrenergic agonists for glaucoma are contraindicated in who? |
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Definition
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Term
| What category of glaucoma drug is most likely o have systemic effects and why? |
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Definition
| cholinergic; absorbed quickly; headache, flushing, increased saliva and sweat |
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Term
| What are signs of overdose when using cholinergic drugs? |
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Definition
| increased drooling or sweating |
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Term
| Cholinergic drugs and carbonic annhydrase inhibitors should not be given to who? |
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Definition
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Term
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Definition
| chemo and radiation together for cancer treatment |
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Term
| combination chemo is aka what? |
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Definition
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Term
ID chemotherapy drug category:
damage cell's DNA and interrupt DNA/RNA synthesis |
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Definition
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Term
ID chemotherapy drug category:
interfere with formation of tubules so cells can't separate during division |
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Definition
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Term
ID chemotherapy drug category:
cross link DNA making them bind tightly inhibiting cell division |
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Definition
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Term
ID chemotherapy drug category:
disrupt enzyme needed for DNA synthesis and cell division |
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Definition
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Term
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Definition
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Term
T/F:
minor infections in chemo patients can be ignored |
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Definition
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Term
ID BRM:
stimulate immune system to destroy cancer cells |
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Definition
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Term
ID BRM:
stimulate natural killer cells slow tumor division |
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Definition
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Term
ID BRM:
reduce formation of blood vessels in tumors |
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Definition
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Term
ID BRM:
induce faster recovery of bone marrow after chemo |
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Definition
| colony stimulating factors |
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Term
| Describe targeted therapy in cancer treatment |
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Definition
| combo of gene and immunotherapy; EGFR and VEGFR, not effective unless cancer cell over expresses the target substance |
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