Term
| acute inflammatory response attracts -- to -- microbes while -- accumulates |
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Definition
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Term
1. Acute inflammatory response-
recognition by --; release -- |
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Definition
Recognition by macrophages; release “help” cytokines
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macrophages
tend to hang out in tissues monitor for unusual activity and consume microbes and send out cytokines to tell other cells. |
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Term
2.Acute inflammatory response-
-- to host cells releases -- |
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Definition
Damage to host cells releases bradykinin
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Bradykinin opens gaps in enothelial single layer of cells lining the blood vessel. The cells on the inside release a series of adhesion molecules that make neutrophiles (most prevelant WBC in blood) slow down and push themselves thru extravasation squeeze thru gaps in cells and release enzyme ending up in tissue where macrophage is. =fluid accumulation. Swelling= edema |
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Term
3. Acute inflammatory response-
cytokines -- |
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Definition
| Cytokines increase endothelial adhesion molecules (ICAM/VCAM) |
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Term
| 4. Acute inflammatory response- |
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Definition
| Rolling WBC stick + stop, squeeze through gaps (extravasation/diapedesis) toward infection/injury |
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Term
| 5. Acute inflammatory response- |
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Definition
| Fluid accumulates (edema=swelling) |
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Term
| 6. Acute inflammatory response- |
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Definition
| Neutrophils phagocytize microbes, die quickly |
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Term
| 7. Acute inflammatory response- |
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Definition
| Pus (cells and blood proteins) forms. |
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Term
| Interferons are a -- response |
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Definition
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Term
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Definition
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Term
| Interferons are -- antiviral -- that help --. # of types |
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Definition
Non-specific Antiviral cytokines help prevent infection.
2 types |
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Term
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Definition
| Inhibit viral RNA production/destroy viral RNA |
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Term
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Definition
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Term
| Fever is caused by -- binding at -- |
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Definition
| Cytokines bind at hypothalamus regulator |
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Term
| What is the benefit to a fever? |
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Definition
| Temperature increases= mesophiles(most pathogens) don’t like above 37 degrees. |
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Term
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Definition
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Term
| A virus that would be effected by type 1 interferons |
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Definition
| influenze- the viral RNA would be destroyed |
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