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301 quiz 4
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60
Biochemistry
Undergraduate 3
05/19/2014

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Term
how are lipids characterized
Definition
hydrophobicity
Term
functions of lipids
Definition
energy storage
membranes
messengers
cushioning
Term
monomer for lipids
Definition
fatty acid
Term
fatty acid
Definition
long hydrocarbon chain with carboxyl chain at the end
Term
saturated fat
Definition
no C=C bonds in fatty acid
Term
unsaturated fat
Definition
C=C bond present in fatty acid
Term
monounsaturated fat
Definition
1 C=C bond present
Term
polyunsaturated fat
Definition
2+ C=C bonds present
Term
is fatty acid protonated or deprotonated at physiological pH
Definition
deprotonated
Term
fatty acid nomenclature rules
Definition
1) chain length
2) how many double bonds
3) where C=C's are located
Term
anoic
Definition
no C=C
Term
enoic
Definition
yes C=C
Term
what are IMF's between lipids
Definition
van der waals
Term
strength of van der waals
Definition
very weak work over a short distance
Term
melting point trends of fatty acids
Definition
as carbon chain length increase melting point increase

as number of C=C's increase melting point decreases
Term
draw basic triglyceride
Definition
glycerol backbone
3 substituent fatty acid or other
Term
adipoacyte
Definition
fat tissue cell
Term
adipose tissue
Definition
stores triglycerides
Term
wax
Definition
fatty acid covalently linked to an alcohol via ester linkage
Term
phosphotidate
Definition
a triglyceride derivitive with 2 fatty acid chains on C1 and C2 and a phosphate group with a substituent on C3
Term
sphingolipids
Definition
an amphiphatic lipid with an fatty acid on C3 an aminated fatty acid on C2 and an esterified head group substituent on C1
Term
shingosine
Definition
a triglyceride derivitave with an amino group of C2 and an OH group on C1
Term
where does phopholipase A1 sever
Definition
between ester linkage and carbonyl at C1 of triglyceride
Term
where does phospholipase A2 sever
Definition
between ester linkage and carbonyl at C2 of triglyceride
Term
where does phospholipase C sever
Definition
between ester linkage and Phosphate on C3
Term
where does phospholipase D sever
Definition
between phosphate and saccharide linkage on C3
Term
diacylglyceride
Definition
DAG gycerol backbone with 2 attached fatty acids
Term
monoacylglyceride
Definition
MAG, glycerol backbone with 1 attached fatty acid
Term
amphipathic
Definition
molecule with both polar and nonpolar character
Term
cholesterol
Definition
major sterol in animal tissues with amphipathic character
Term
what are cholesterols useful for
Definition
making steroids and hormones
Term
how are lipids seperated
Definition
extracted in a solution of H2O and MeOH and chloroform, lipids dissolve in chloroform and can be seperated in sep funnel
Term
adsorption chromatography (column chromatography)
Definition
type of reversed phase column chromatography, lipids placed into a silicic acid column, polar lipids bind to silicic acid, hydrophobic lipids exit column first
Term
lipid gas chromatography
Definition
lipids placed into gc with inert material, lipids with same character of inert material dissolve in it, lipids with non-similar character are carried off by inert gas.
Term
chromosomes
Definition
a single DNA molecule and associating proteins that contains genes, stores and transmits genetic information
Term
gene
Definition
is the DNA that encodes the primary sequence of some final product (a protein, polypeptide or RNA)
Term
1 gene encode one product
Definition
Term
wild type sequence
Definition
the natural sequence of a gene
Term
virus
Definition
infectious parasties consisting of a genome surrounded by a protein coat
Term
DNA virus
Definition
virus with DNA as its genetic material, relies on replication with specific DNA polymerase
Term
RNA virus
Definition
virus that uses RNA as genetic material
Term
plus strand
Definition
RNA genome is transcribed
Term
minus strand
Definition
RNA genome is used to make RNA template to be transcribed
Term
retrovirus
Definition
RNA is reverse transcribed to cDNA then inserted into host genome
Term
karyotype
Definition
set of an individuals chromosomes
Term
translocation
Definition
exchange of DNA between two different locations
Term
intron
Definition
RNA sequence that gets removed by RNA splicing
Term
exons
Definition
RNA sequences that are not spliced out and encode the gene product
Term
satellite DNA
Definition
short sequence repeated thousands of times
Term
telomere
Definition
specialized sequences at the end of a gene that help stabilize a chromosome
Term
centromere
Definition
sequence of DNA that serves as attachment point for proteins that link the chromosome to the mitotic spindel
Term
DNA topography
Definition
shape of DNA
Term
supercoiling
Definition
DNA coils coiling around each other
Term
relaxed state
Definition
axis of DNA coil does not cross itself, no supercoiling
Term
linking number
Definition
the number of times a two curves wind around each other
Term
what type of coiling does underwinding cause
Definition
negative supercoils
Term
what type of coiling does overwinding cause
Definition
positive supercoils
Term
negative supercoil
Definition
negative change in linking number(- sigma)
Term
positive supercoil
Definition
positive change in linking number (+sigma)
Term
superhelical density formula
Definition
sigma=dLk/Lko
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