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#2: Chemical bonds and macromolecules
Biology study for midterm
17
Biology
Undergraduate 1
09/27/2014

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Term
Peptide
Definition
The covalent bond between the carboxyl group and the amino group on another formed by a dehydration reaction.
Term
Protein
Definition
A biologically functional molecule molecule consisting of one or more polypeptides folded and coiled into specific 3D structures.
Term
nucleotide
Definition
The building block of a nucleic acid, consisting of a 5-carbon sugar covalently bonded to a nitrogenous base and one or more phosphate groups.
Term
phospholipid
Definition
A lipid made up of a glycerol joined to two fatty acids and a phosphate group. The hydrocarbon chains of the fatty acids act as non polar, hydrophobic tails and the rest of the body acts as a hydrophilic polar head. The form bilayers that act as biological membranes.
Term
triacylglycerol
Definition
A lipid consisting of three fatty acids linked to one glycerol molecule; also called a fat or triglyceride.
Term
polymer
Definition
A long molecule consisting of many similar or identical monomers linked together by covalent bonds.
Term
monomer
Definition
The subunit that serves as the building block of a polymer
Term
glycosidic bond
Definition
A covalent bond formed between two monosaccharides by a dehydration reaction.
Term
Peptide
Definition
A compound of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another
Term
phosphodiester bond
Definition
Not a precise term. Refers to any molecule in which two parts are joined through a phosphate group.

Examples are found in rNA, dNA, phospholipids, cyclic nucleotides, nucleotide diphosphates and triphosphates.
Term
hydrophobic
Definition
Having no affinity for water.
Term
Hydrophilic
Definition
Having an affinity for water
Term
amphipathic
Definition
Having both a hydrophilic region and a hydrophobic region
Term
primary structure
Definition
The level of protein structure referring to a specific linear sequence of amino acids
Term
secondary structure
Definition
Regions of repeative coiling or folding of the polypeptide backbone of a protein due to hydrogen bonding between constituents of the backbone.
Term
tertiary structure
Definition
The overall shape of a protein molecule due to interactions of amino acid side chains, including hydrophobic interactions, ionic bonds, hydrogen bonds, and disulfide bridges.
Term
quaternary structure
Definition
The particular shape of a complex, aggregate protein, defined by the characteristic 3D arrangement of its constituent sub-units, each a polypeptide.
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