| Term 
 
        | 3 Stage of brain development are |  | Definition 
 
        | Cytogenesis-Histogenesis-Organogenesis |  | 
        |  | 
        
        | Term 
 
        | In which stage congenital malformations can result when alterations occur |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | The portion of nervous system containing brain and spinal core that develops from the neural plate what is this system? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is the central nervous system develops? |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | the thick layer of ectodermal tissue giving rise to neral tube and brain, spinal core tissues of CNS |  | 
        |  | 
        
        | Term 
 
        | When does the neural plate develops? |  | Definition 
 
        | 18-20 days after conception |  | 
        |  | 
        
        | Term 
 
        | The longitudinal  tube giving rise to brain, spinal core, neural tissue of CNS formed by fusion of the neural folds and paired longitudinal folds uniting to form of what ? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is the neural crest? |  | Definition 
 
        | Cells along outer surface of neural tube |  | 
        |  | 
        
        | Term 
 
        | Neural tube differentiates into _____ |  | Definition 
 
        | CNS (brain and spinal core) |  | 
        |  | 
        
        | Term 
 
        | Neural crest differentiates into____ |  | Definition 
 
        | Peripheral nervous system |  | 
        |  | 
        
        | Term 
 
        | when the neural tube formation and closure? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | How is the neural tube formation/closure ? |  | Definition 
 
        | The neural plate folds on itself, closes dorsally |  | 
        |  | 
        
        | Term 
 
        | Which part of neural tube close first? When it close? |  | Definition 
 
        | The cranial end-24days after conception |  | 
        |  | 
        
        | Term 
 
        | Which part of neural tube close second? When it close? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | The cranial end of tube becomes ____ |  | Definition 
 
        | Ventricular system of brain |  | 
        |  | 
        
        | Term 
 
        | The Caudal end of tube becomes __ |  | Definition 
 
        | Central canal of spinal cord |  | 
        |  | 
        
        | Term 
 
        | When is the greatest growth occurs at cranial end? |  | Definition 
 
        | End of 4th week gestation |  | 
        |  | 
        
        | Term 
 
        | What is the cranial end growth differentiates into? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are the 3 primary brain vesicles? |  | Definition 
 
        | Prosencephalon (forebrain), mesencephalon (midbrain), and rhombencephalon (hindbrain) |  | 
        |  | 
        
        | Term 
 
        | 4 region of cerebral cortex are_ |  | Definition 
 
        | Frontal lobe-Parietal lobe-Occipital lobe_Temporal lobe |  | 
        |  | 
        
        | Term 
 
        | What is diverticula mean? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Diverticulation occurs at ___in prosencephalon (forebrain) and forms___   |  | Definition 
 
        | 5-6 wks gestion telencephalon and diencephalon |  | 
        |  | 
        
        | Term 
 
        | what is the telencephalon? |  | Definition 
 
        | Endbrain-gives rise to cerebral hemisphere, lateral ventricles and basal ganglia |  | 
        |  | 
        
        | Term 
 
        | What is the diencephalon? |  | Definition 
 
        | In between brain- forms thalamus and hypothalamus |  | 
        |  | 
        
        | Term 
 
        | what is the rhombencephalon? |  | Definition 
 
        | Hindbrain divides into mestencephalon and myelencephalon |  | 
        |  | 
        
        | Term 
 
        | what are the Metencephalon and Myelencephalon? |  | Definition 
 
        | The lower part or hindbrain from which medulla oblongata develops |  | 
        |  | 
        
        | Term 
 
        | Indication for neonate brain exam are |  | Definition 
 
        | Congenital anomaliles-Intracranial hemorrhage-Intracranial masses-Venous malformations-Hydrocephalus-Intracranial infections-Infarction and/ or edema |  | 
        |  | 
        
        | Term 
 
        | Which is direction of scan in coronal plane? |  | Definition 
 
        | Sweep anterior to posterior  and maintain symmetry with transducer place transversely on the fontanelle |  | 
        |  | 
        
        | Term 
 
        | Which is direction of scan in sagital plane? |  | Definition 
 
        | Scan and take midline image first then scan to right and left to take image on right and left side with transducer place longitudinally across anterior fontanelle |  | 
        |  | 
        
        | Term 
 
        | A congenital anomaly associated with spina bifida is called |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Chiari malformation is when___ |  | Definition 
 
        | Cerebellum and brain stem pulled toward the spinal cord and secondary hydrocephalus develops |  | 
        |  | 
        
        | Term 
 
        | Chiari Malformation is characterized by__ |  | Definition 
 
        | Displacement of 4th ventricle and upper medullar -->cervical canal Displacement of the inferior part of the cerebellum --> the foramen magnum Defect in the calvarium and spinal column |  | 
        |  | 
        
        | Term 
 
        | Chiari malformation is associated with __ |  | Definition 
 
        | Myelomeningocele, hydrocephalus, dilation of the third ventricle, and absence of CSP (cavum septum pellucidum) |  | 
        |  | 
        
        | Term 
 
        | What is myelomeningocele ? |  | Definition 
 
        | Neural tissue and meninges protrude |  | 
        |  | 
        
        | Term 
 
        | The most common type of chiari malformation is |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | Banana sign of cerebellum |  | 
        |  | 
        
        | Term 
 
        | Ultrasound finding of Chiari II include: |  | Definition 
 
        | Small posterior fossa, and small cerebellum Displacement of cerebellum -->foramen magnum Enlarge massa intermedia and ventricles Partial absence of CSP Myelomeningocele Hydrocephalus |  | 
        |  | 
        
        | Term 
 
        | Incomplete cleavage of primitive forebrain into 2 cerebral hemispheres and characterized by grossly abnormal brain with common large central ventricle this is____ |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are 3 type of holoprosencephaly ? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | The most severe form of Holoprosencephaly is |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | There are multiple facial anomalies, most severe, thalami are fused; no falx, corpus callosum or interhemispheric fissure present; and the third ventricle is absent these are characteristic of___ |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Dilated 4th ventricle in direct communication with cisterna magnum, huge 4th ventricle cyst at cerebellum usually lies, small or absenct cerebellar vermis; Hydrocephalus and elevated tentorium all these are___ |  | Definition 
 
        | Dandy-Walker Malformation |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Agenesis of corpus callosum |  | 
        |  | 
        
        | Term 
 
        | Depending on timing this can be partial or complete, this highly associate with central nervous system (CNS) anomalies What is this? |  | Definition 
 
        | Agenesis of corpus callosum |  | 
        |  | 
        
        | Term 
 
        | What is ultrasound finding of ACC?   |  | Definition 
 
        | Narrow frontal horns (slitlike) Absent CSP Widely separated, parallel lateral ventricles |  | 
        |  | 
        
        | Term 
 
        | Enlargement of ventricular system; imbalance between production and drainage of CSF this is ___ |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | If the earlier hydrocephalus occurs the greater ___ |  | Definition 
 
        | enlargement of the head present |  | 
        |  | 
        
        | Term 
 
        | The dilation of ventricles/ hydrocephalus results in__ |  | Definition 
 
        | Widely separated sutures and huge, bulging fontanelles |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | US finding of hydrocephalus are |  | Definition 
 
        | Blunting of the lateral angles of the lateral ventricles, dilated ventricle atrium >10mm or 1cm |  | 
        |  | 
        
        | Term 
 
        | What are types of hydrocephalus? |  | Definition 
 
        | Obstructive and communicating |  | 
        |  | 
        
        | Term 
 
        | Interference of the circulation of CSF in the ventricular system causes enlargement of the ventricular cavities proximal to the obstruction is what type of hydrocephalus? |  | Definition 
 
        | Obstructive hydrocephalus |  | 
        |  | 
        
        | Term 
 
        | CSF pathways are open but there is decrease absorption of CSF The entire ventricular system uniformly distended What is hydrocephalus type? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | When the Germinal Matrix hemorrhage is most at risk? |  | Definition 
 
        | GA: < 30 weeks of gestation  Weight <1500g or both occur |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | The network of blood vessels and primitive neural tissue This is very sensitive to pressure and metabolic changes which can rupture vessels |  | 
        |  | 
        
        | Term 
 
        | When the hemorrhage of germinal Matrix most occur in? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | When is the optimally first US screening check for hemorrhage of Germinal Matrix and Hydrocephalus done at? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | When is the second screening done to check for periventricular leukomalacia and ventricular enlargement? |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | Periventricular leukomalacia |  | 
        |  | 
        
        | Term 
 
        | How many grading level of germinal matrix hemorrhage? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Subependymal hemorrhage (SEH) is |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Intraventricular extension without hydrocephalus is |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Intraventricular hemorrhage with hydrocephalus is |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Intraparenchymal hemorrhage is |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Ultrasound finding grade I of (GMH) hemorrhage is |  | Definition 
 
        | Homogeneous; moderately to highly echogenic mass Usually in the caudothalamic groove Echogenicity of clot changes over time (less echogenic with anechoic center) |  | 
        |  | 
        
        | Term 
 
        | Ultrasound finding grade II of (GMH) hemorrhage is |  | Definition 
 
        | Hyperechoic clot fills a portion of ventricle or all of ventricle Choroid plexus may appear asymmetrically thick and difficult to separate choroid plexus from clot Appearance changes over time |  | 
        |  | 
        
        | Term 
 
        | Ultrasound finding grade III of (GMH) hemorrhage is |  | Definition 
 
        | Clot then choroid plexus more defined May be adherent to wall or move to dependent position Hydrocephalus |  | 
        |  | 
        
        | Term 
 
        | Ultrasound finding grade IV of (GMH) hemorrhage is |  | Definition 
 
        | Usually in cerebral cortex Venous infarction secondary to hemorrhage Acute echogenic homogenous mass extending into brain parenchyma Over-time echogenic rim with anechoic center |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Infarction and necrosis of periventricular white matter this most frequent ischemic lesion in immature brain Associate with crebral palsy |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | PVL is most frequent ischemic lesion in__ |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Within 2 weeks of insult, PVL ultrasound finding are: |  | Definition 
 
        | Increased echogenicity of periventricular white matter greater than choroid plexus |  | 
        |  | 
        
        | Term 
 
        | Ultrasound finding at 2-4 weeks of PVL___ |  | Definition 
 
        | Cystic changes may develop single or multiple cysts lateral and superior to top of ventricles and usually bilateral and symmetrical |  | 
        |  | 
        
        | Term 
 
        | The main concern with premature infants is |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | How many percentage chance of hemorrhage in brain if infants born <34 weeks? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Neonatal brain ultrasound is for |  | Definition 
 
        | Neonates with difficult delivery or born prematurely |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | The segment extends posteriorly from the trigone |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | The segment is divided posteriorly by foramen on Monro near the body of the vent and roof is corpus callosum |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | The segment extends anteriorly from trigone through the temporal lobe |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | The anterior, occipital and temporal horns join here, and here is where the ventricle measurements are taken |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | small, thin arrowhead shape, midline cavity that contains CSF and is connected to the 3rd ventricles by the aqueduct of sylvius |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Small, teardrop-shaped, midline cavity that lies between thalami, contains CSF and connected to lateral ventricles via foramen of Monro |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Found on posterior tip of cavum septum pellucidi |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Tail of choroid plexus; major site for bleeds |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Midline channel connecting 3rd and 4th ventricles; rarely seen sonographically |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Midline channel connecting the 3rd ventricle with each lateral ventricle |  | 
        |  | 
        
        | Term 
 
        | The Middle cerebral artery (MCA) and circle of Willis is |  | Definition 
 
        | Often evaluated with Doppler to determine cerebral blood flow patterns |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Pea-shaped structure suspended within 3rd ventricle and best seen with ventricular dilation |  | 
        |  | 
        
        | Term 
 
        | The tentorium cerebelli is |  | Definition 
 
        | The structure separates the cerebellum from the cerebrum |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | The innermost membrane that is highly vascularized |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Thin, delicate layer between 2 other membranes, surrounded by spaces for CSF |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Double layered outer membrane, toughest barrier |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | 3 membranes that surround and protect the brain |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Spaces between the bones of the skull; not completely closed in neonate |  | 
        |  | 
        
        | Term 
 
        | The quadrigeminal fissure is |  | Definition 
 
        | located posterior and inferior from cavum vergae |  | 
        |  | 
        
        | Term 
 
        | The interhemispheric fissure is |  | Definition 
 
        | Contains the falx cerebri, separates the 2 hemispheres |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Bilateral located between temporal and frontal lobes; resembles an echogenic "Y" turned on its side, location of MCA |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | 2 ovoid egg-shaped structures located on either side of the 3rd ventricle superior to brain stem; relay station for upward moving senory impulses |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | under thalamus; regulates body temperature, fluid balance and metabolism; center for thirst .. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | The narrow portion of brain stem that connects forebrain to hindbrain; contains 2 halves called cerebral peduncles |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Structure lies in posterior fossa under tentorium; its 2 hemispheres are connected by the vermis; has cauliflower appearance |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Part of dura mater and found in the interhemispheric fissure; this fibrous structure separating the 2 cerebral hemispheres |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | 2 located on either side of the brain; this is largest CSF cavities within the cerebral hemispheres and divided into 4 segments |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | The segment extends from foramen of Monro to the trigone; the corpus callosum forms the roof and CSP (cavum septum pellucidum) forms the medial wall |  | 
        |  | 
        
        | Term 
 
        | Cerebral spinal fluid are |  | Definition 
 
        | Surrounded and protected the brain and spinal cord, 40% formed by choroid plexus of lateral, third and fourth ventricle |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Echogenic cells important in CSF production found in atrium of lateral ventricles; and regulated intraventricular pressure by secretion or absorption of CSF |  | 
        |  | 
        
        | Term 
 
        | Cavum septum pellucidum (CSP) is |  | Definition 
 
        | Thin, triangular-shaped (coronally), comma-shaped (sagitally) and lies between frontal horns and bodies of the lateral ventricles in midline; forms the floor of corpus callosum and filled with CSF and usually closes within 3-6 months of life |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Small,fluid-filled space immediately posteroinferior to cerebellum; found between medulla oblongata, cerebellar hemispheres and occipital bone |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Group of nerve fibers (mass of white matter) connecting right and left hemispheres; superior to 3rd ventricle; forms roof of lateral ventricle and sits on top of cavum septum pellucidum |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Primary motor area, located anterior to cental fissure Controls the movements of the conscious skeletal muscles such as face, mouth, and hands. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | The posterior part interprets visual impulses |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Cortical areas, responsible for interpreting impulses from the special sense organs such as the auditory area and olfactory area |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Contains the body's sensory receptors which interpret the impulses that allow one to recognize such sensations as pain, cold or a light touch |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Cerebral hemispheres Diencephalon Brain stem Cerebellum |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Enclosed space serving as a reservoir for cerebrospinal fluid |  | 
        |  | 
        
        | Term 
 
        | Transducer should be utilized is |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Advantage over CT/MRI include: |  | Definition 
 
        | Portability Lower cost Speed No ionizing radiation and no sedation |  | 
        |  | 
        
        | Term 
 
        | Sonography is essential for |  | Definition 
 
        | New born, high risk, and unstable premature infant |  | 
        |  |