Term
|
Definition
-Volume inc (inc preload)
-Vasoconstriction (inc aftrload)
-Cardiac Remodeling |
|
|
Term
|
Definition
-Volume inc (inc preload)
-Cardiac Remodeling |
|
|
Term
|
Definition
-Vasoconstriction (inc aftrload)
-Cardiac Remodeling
-HR inc (Contractility inc) |
|
|
Term
| -Volume inc (inc preload) does |
|
Definition
| pulmonary/systemic congestion |
|
|
Term
| -Vasoconstriction (inc aftrload) does |
|
Definition
-dec SV
-INC MVO2 (inc O2 demand) |
|
|
Term
|
Definition
|
|
Term
| -HR inc (Contractility inc) does |
|
Definition
-INC MVO2 (inc O2 demand)
-ARRYTHMIAS |
|
|
Term
|
Definition
REDUCE HR
-reduce cardiac wrk
-dec O2 Myocard consumption
-Red Renin(RAAS) |
|
|
Term
|
Definition
REDUCE HR
BLOCKS LEAKY IF CURRENT.REDUCE ANGINA.SLOWS SA NODE POTENTIAL
-reduce cardiac wrk
-dec O2 Myocard consumption |
|
|
Term
|
Definition
REDUCE BP
-dec O2 Myocard consumption
-red card wrk |
|
|
Term
|
Definition
LOW DOSES BLOCKS EXCESSIVE SNS ACTIVATION CNS
-RED HR,VASOCONSTR, RENIN SECR
-RED SYMPATHETIC OUTFLOW
-IMPROVE IMPAIRED BARORECEPTOR FUNC |
|
|
Term
|
Definition
INC Na+ INTRACELL
-DEC Na+/Ca2+ exchng
-causes inc in intracell Ca2+
-inc myocite force of contract |
|
|
Term
| Glycosides used in these pts for improvement |
|
Definition
|
|
Term
|
Definition
fibrosis
-generation of ROS(reac ox spec) |
|
|
Term
NEprilysin inhibitors
(used w/ ARBs) |
|
Definition
inhibit metalloprotease Neprilysin.
-stop neprilysin from degrading BNP & ANP |
|
|
Term
|
Definition
-oppose RAAS
-Inc Vasodilation
-Natriuretic peptides--->ANP(atria)
BNP(ventricles) |
|
|
