Term
|
Definition
Terbutaline
Class: Adrenergic agonist
Bronchodilator
Tocoylytic
|
|
|
Term
|
Definition
Stimulates Beta-2 adrenergic receptors
Causes relaxation of uterine and bronchial smooth muscle |
|
|
Term
|
Definition
Terbutaline
indications: Bronchospasm
Pre term labor
|
|
|
Term
Terbutaline
standard prep
dosage/ route
|
|
Definition
Terbutaline
Standard prep:
1mg/ml
Dosage/route:
*Preterm labor: 2.5-10 mcg/min IV…increased to 17.5-30mcg/min over 15-20 min.
*Bronchospasm: 0.25mg SC…repeat in 15-30 min. (MAX 0.5mg/hr)
*PALS: 0.005-0.01mg.kg SC…repeat in 15-20 min X2 only! (MAX DOSE: 0.4mg!!!)
|
|
|
Term
Terbutaline
Adverse effects
|
|
Definition
Terbutaline
adverse effects:
*Paradoxical bronchoconstriction w/ excessive use
*Tremors
*Anxiety
*Palpitations
*Tachycardia
*CP
*Increased BP
*Diaphoresis
*HA
*Nausea
*Dizziness
*Oral/pharyngeal dryness when inhaled |
|
|
Term
|
Definition
Terbutaline
Precautions:
Cardiovascular disease
*HTN
*Diabetes
*SZ
*Hypothyroidism |
|
|
Term
Terbutaline
Contraindications |
|
Definition
Terbutaline
Contraindications:
*Hypersensitivity to sympathomimetics
|
|
|
Term
Succinylcholine(Anectine)
Class |
|
Definition
Succinylcholine
Class
Depolarizing neuromuscular blocker |
|
|
Term
Succinylcholine(Anectine)
MOA |
|
Definition
Succinylcholine(Anectine)
MOA:
*Ultra-short acting agent w/ high affinity for AcH receptor
*Causes depolarization by stimulating cholinergic receptors @ NICOTINIC motor end plate
*Depolarization causes flaccid skeletal muscle paralysis as long as succinylcholine is present @ site
*Hydrolyzed by PLASMA CHOLINESTERASE |
|
|
Term
Succinylcholine(Anectine)
Indications |
|
Definition
Succinylcholine (Anectine)
Indications:
PATI Protocol |
|
|
Term
Succinycholine (Anectine)
Contraindications |
|
Definition
Succinylcholine (Anectine)
Contraindications:
Hypersensitivity
Hyperkalemia
>48 hrs post trauma/burn
Malignant hyperthermia
Lower neuromuscular degenerative disease
open globe injury
plasma cholinterase deficiency |
|
|
Term
Succinylcholine (Anectine)
Standard prep
Dosage/ Route |
|
Definition
*Succinylcholine (Anectine)*
Standard Prep
200 mg/ 10 ml
Dosage Route
1.5 mg/ kg IV
Double dose for IM
ACLS: 1-2 mg/ kg IV (x 2=IM)
PALS: 1.0-1.5 mg/ IV (x 2=IM)
PALS-Infants: 2 mg/ kg IV (x 2=IM)
Lasts 3- 5 min!!! |
|
|
Term
Succinylcholine (Anectine)
Adverse Effects |
|
Definition
Succinylcholine (Anectine)
Adverse effects
Cardiac arrest
Bradycardia
Rhabdomyosis
Hyperkalemia
Increased....ICP, intraocular & intragastric pressure
Increased BP |
|
|
Term
Succinylcholine (Anectine)
Interactions |
|
Definition
Succinylcholine (Anectine)
Interactions
Meds that decrease plasma cholinterase activity
Electrolyte abnormalities/ Digitalis toxicity ---
Cardiac Arrythmias secondary to Hyperkalemia |
|
|
Term
|
Definition
Sodium thiosulfate
Class
Crystalline compound |
|
|
Term
|
Definition
Sodium Thiosulfate
MOA
Provides SULFUR needed to accelerate conversion of Cyanide--THIOCYANATE (less toxic)
Enhances RHODANESE enzyme which takes Sulfate from the Na+ thiosulfate and transfers it to Cyanide to make THIOCYANATE (excreted via Kindeys) |
|
|
Term
Sodium Thiosulfate
Indications |
|
Definition
Sodium Thiosulfate
Indications
Cyanide exposure |
|
|
Term
Sodium Thiosulfate
Contraindications |
|
Definition
Sodium Thiosulfate
Contraindications
Severe anemia
Methemaglobinemia |
|
|
Term
Sodium Thiosulfate
Standard Prep
Dosage / Route |
|
Definition
Sodium Thiosulfate
Standard Prep
12.5 G/ 50 mls
Dosage/ Route
12.5 G IV |
|
|
Term
Sodium Thiosulfate
Adverse Effects |
|
Definition
Sodium Thiosulfate
Adverse effects
Hypotension
Dizziness
Syncope
N/V
Flushing
Tachycardia
Psychosis
CNS depression |
|
|
Term
Sodium Thiosulfate
Interactions |
|
Definition
Sodium Thiosulfate
Interactions
ACE inhibitors
*Angiotensin receptor blockers
*Ca+ channel blockers
*Alpha blockers
*BB
*Diuretics
*Anti-platelet meds
*Erectile dysfunction meds |
|
|
Term
Sodium Thiosulfate
Precautions |
|
Definition
Sodium Thiosulfate
Precautions
HTN
Hyptotension
Head Injury
Recent MI
Elderly
Carbon Monoxide poisoning |
|
|
Term
Sodium Bicarbonate (NaHCO3):
Class: |
|
Definition
Sodium Bicarbonate (NaHCO3):
Class:
*Alkalizing agent
*Electrolyte replacement
|
|
|
Term
Sodium Bicarbonate (NaHCO3)
MOA |
|
Definition
NaHCO3
MOA
Dissociates into Na+ and Bicarbonate ions w/ increased H+ ions (acidosis), bicarbonate ions combine w/ H+ to make CARBONIC ACID
Carbonic acid dissociates to CO2 & H2O--excreted by lungs |
|
|
Term
Sodium Bicarbonate (NaHCO3)
Indications |
|
Definition
Sodium Bicarbonate (NaHCO3)
Indications
PEA
*Asystole
*Renal dialysis code
*ACLS: HyperK+
*DKA
*Tricyclic antidepressant or ASA OD
*Cocaine OD
*Diphenhydramine OD
*Na+ channel blocker toxicity
|
|
|
Term
Sodium Bicarbonate NaHCO3
Contraindications |
|
Definition
NaHCO3
Contraindications
Metabolic / Respiratory alkalosis
Hypocalcemia |
|
|
Term
Sodium Bicarbonate NaHCO3
Standard Prep
Dosage / Rout |
|
Definition
Sodium Bicarbonate NaHCO3
Standard Prep
50 mEq / 50 ml
Dosage / Route
PEA & Asystole: 1 mEq / kg IV
Renal code: 1 mEq / kg IV repeated x 1 prn
Pals: 1 mEq / kg |
|
|
Term
Sodium Bicarb
Adverse Effects |
|
Definition
NaHCO3
Adverse Effects:
*Alkalosis--Causes Oxyhemaglobin dissociation curve to shift LEFT (O2 attaches to hemoglobin more readily. Decreases tissue perfusion)
*Peridoxical ACIDOSIS!
*If Carbonic acid passes blood-brain barrier and THEN dissociates to H2O & CO2, which can’t cross barrier, ions are trapped--CNS depression. |
|
|
Term
Sodium Bicarbonate
Precautions |
|
Definition
NaHCO3
Precautions:
*Catacholemines deactivated in alkaline environments
*Can cause HYPERNATREMIA
*Precipitates in presence of Ca+ chloride
*Produces CO2…must have adequate ventilation!
|
|
|
