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2006 ACLS Drug Indications
2006 ACLS Drug Indications
18
Medical
Professional
02/25/2013

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Term
ACLS 2006 Indications for Oxygen.
Definition
-Any suspected cardiopulmonary emergency
-Complaints of shortness of breath and suspected ischemic chest pain
-ACS: administer to all patients for first 6 hours. Continue if pulmonary congestion, ongoing ischemia, or oxygen saturation is <90%
-For patients with suspected stroke and hypoxemia or unknown oxyhemogloblin saturation. May consider administration to patients who are not hypoxemic.
Term
ACLS 2006 Indications for Epinephrine.
Definition
-Cardiac arrest: VF, pulseless VT, asystole, pulseless electrical activity.
-Symptomatic bradycardia: Can be considered after atropine as an alternative infusion to dopamine.
-Severe hypotension: Can be used when pacing and atropine fail, when hypotension accompanies bradycardia, or with phosphodiesterase enzyme inhibitor.
-Anaphylaxis, severe allergic reactions: Combine with large fluid volumes, corticosteroids, antihistamines.
Term
ACLS 2006 Indications for Atropine.
Definition
-First drug for symptomatic sinus bradycardia
-May be beneficial in presence of AV nodal block or ventricular asystole. (Will NOT be effective for infranodal {Mobitz type II} block)
-Second drug (after epinephrine or vasopressin) for asystole or bradycardic pulseless electrical activity.
-Organophosphate (eg, nerve agent) poisoning: extremely large doses may be needed.
Term
ACLS 2006 Indications for Lidocaine.
Definition
-Alternative to amiodarone in cardiac arrest from VF/VT.
-Stable monomorphic VI with preserved ventricular function
-Stable polymorphic VT with normal baseline QT interval and preserved LV function when ischemia is treated and electrolyte balance is corrected.
-Can be used for stable polymorphic VT with baseline QT interval prolongation if torsades suspected.
Term
ACLS 2006 Indications for Procainamide.
Definition
-Useful for treatment of a wide variety of arrhythmias, including stable monomorphic VT with normal QT interval and preserved LV function.
-May use for treatment of PSVT uncontrolled by adenosine and vagal maneuvers if blood pressure stable.
-Stable wide-complex tachycardia of unknown origin.
-Atrial Fibrillation with rapid rate in WPW syndrome
Term
ACLS 2006 Indications for Vasopressin.
Definition
-May be used as an alternative pressor to epinephrine in the treatment of adult shock-refractory VF.
-May be useful alternative to epinephrine in asystole, PEA.
-May be useful for hemodynamic support in vasodilatory shock (e.g, septic shock)
Term
ACLS 2006 Indications for Adenosine.
Definition
-First drug for most forms of stable narrow-complex PSVT. Effective in terminating those due to reentry involving AV node or sinus node.
-May consider for unstable for narrow-complex reentry tachycardia while preparations made for cardioversion.
-Wide-complex regular tachycardia, thought to be or previously defined to be, reentry SVT.
-Does not convert atrial fibrillation, atrial flutter, or VT.
-Undefined, stable narrow-complex SVT as a diagnostic maneuver.
Term
ACLS 2006 Indications for Magnesium.
Definition
-Recommended for use in cardiac arrest only if torsades de pointes or suspected hypomagnesemia is present
-Life-threatening ventricular arrhythmias due to digitalis toxicity
-Routine administration in hospitalized patients with AMI is NOT recommended.
Term
ACLS 2006 Indications for Sodium Bicarbonate.
Definition
-Known preexisting hyperkalemia
-Known preexisting bicarbonate responsive acidosis, tricyclic antidepressant or aspirin overdose, cocaine, or diphenhydramine.
-Prolonged resuscitation with effective ventilation upon return of spontaneous circulation after long arrest interval.
-Not useful or effective in hypercarbic acidosis (eg cardiac arrest and CPR without intubation)
Term
ACLS 2006 Indications for Morphine.
Definition
-Chest pain with ACS unresponsive to nitrates
-Acute cardiogenic pulmonary edema (if blood pressure is adequate)
Term
ACLS 2006 Indications for Norepinephrine.
Definition
-Severe cardiogenic shock and hemodynamically significant hypotension (systolic blood pressure <70 mmHg) with low total peripheral resistance.
-Agent of last resort for management of ischemic heart disease and shock
Term
ACLS 2006 Indications for Dopamine.
Definition
-2nd line drug for symptomatic bradycardia (after atropine).
-Use for hypotension (systolic blood pressure < 70 to 100 mmHg) with signs and symptoms of shock.
Term
ACLS 2006 Indications for Dobutamine.
Definition
Consider for pump problems (congestive heart failure, pulmonary congestion) with systolic blood pressure of 70 to 100 mmHg and no signs of shock.
Term
ACLS 2006 Indications for Isoproterenol.
Definition
-Use cautiously as temporizing measure if external pacer is not available for treatment of symptomatic bradycardia
-Refractory torsades de pointes unresponsive to magnesium sulfate
-Temporary control of bradycardia in heart transplant patients (denervated heart unresponsive to atropine)
-Poisoning from B-Blockers
Term
ACLS 2006 Indications for Nitroglycerin.
Definition

 

 

-Initial antianginal for suspected ischemic pain.

-For intial 24 to 48 hours in patients with AMI and CHF, large anterior wall infarction, persistent or recurrent ischemia, or hypertension.

-Continued use (beyond 48 hours)for patients with recurrent angina or persistent pulmonary congestion. -Hypertensive urgency with ACS.

Term
ACLS 2006 Indications for Furosemide.
Definition
-For adjuvant therapy of acute pulmonary edema in patients with systolic blood pressure >90 to 100 mmHg (without signs and symptoms of shock)
-Hypertensive emergencies
-Increased intracranial pressure.
Term
ACLS 2006 Indications for Tissue Plaminogen Activator.
Definition
-For AMI in adults
o ST Elevation (>1 mm in >2 contiguous leads) or new or presumably new LBBB.
o In context of signs and symptoms of AMI
o Time from onset of symptoms < 12 hrs
-For Acute Ischemic Stroke
o Sudden onset of focal neurologic deficits or alterations in consciousness (eg facial droop, arm drift, abnormal speech).
o Absence of intracerebral or subarachnoid hemorrhage or mass effect on CT scan.
o Absence of variable or rapidly improving neurologic deficits.
o Alteplase can be started in < 3 from symptom onset.
Term
ACLS 2006 Indications for Nitroprusside.
Definition
-Hypertensive crisis
-To reduce afterload in heart failure and acute pulmonary edema.
-To reduce afterload in acute mitral or aortic valve regurgitation
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