Term
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Definition
STAPH: a superficial infection of a hair follicle. It is
characterized by inflammation & abscess formation |
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Term
|
Definition
STAPH: a deep localized infection of a hair follicle or
sebaceous gland. It is characterized by intense
inflammation and the formation of an abscess |
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Term
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Definition
STAPH: multiple
furuncles in skin |
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Term
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Definition
STAPH:a large, hard, intensely
inflamed, localized abscess
in skin and the underlying
connective tissue .
formed by the
progressive spread of one or
more furuncles.
require surgical drainage of the pus,
and should be treated with antibiotics. |
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Term
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Definition
STAPH:superficial infection of skin
characterized by inflammation
and formation of vesicles which
rupture and form crusts (scabs).
caused by S.
aureus or group A streptococcus.
A. S. aureus is the most common
cause of impetigo in children
under 2 years |
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Term
|
Definition
STAPH:spreading infection in soft connective tissue. It is
characterized by redness and swelling (inflammation).
2. Staphylococcus aureus and Group A streptococcus |
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Term
| Staphylococcal Scalded Skin Syndrome |
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Definition
STAPH:a life-threatening
condition in which large
sheets of skin peel away
from the body.
A. It is caused by the
secretion of the exotoxin
*exfoliatin* by S. aureus.
kids under 2 |
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Term
Infective
Endocarditis (IE) |
|
Definition
STAPH:because S.a.
cells that enter the
bloodstream
readily colonize
fibrin repaired
endothelium.
acute (severe symptoms) or
subacute (low grade, chronic symptoms) |
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Term
|
Definition
STAPH:Osler nodes are painful, 0.5 cm
diameter vascular lesions on the
fingers or toes |
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Term
|
Definition
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Term
|
Definition
| STAPH: S. aureus infection of a bone causes inflammation in the bone |
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Term
|
Definition
STAPH:prevents S.a. cells from being opsonized by S.a.-
specific IgG and complement. |
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Term
|
Definition
STAPH:binds the soluble blood
protein fibrinogen and converts it into an insoluble
fibrin coat around S. aureus cells |
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Term
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Definition
| STAPH:Triggers blood and fibrinogen clotting |
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Term
|
Definition
STAPH:Breaks down hyaluronic acid which is the major
component of the intercellular matrix that holds cells
together in connective tissue. |
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Term
|
Definition
STAPH:. Dissolves fibrin threads in blood clots, allowing S.
aureus to free itself from clots and spread in tissue. |
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Term
|
Definition
STAPH:Digest lipids, which enables staphylococci to grow
on the skin’s surface, in hair follicles and in
sebaceous glands |
|
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Term
| beta-lactamase (penicillinase). |
|
Definition
STAPH:Breaks down penicillin.
B. Allows staphylococci that produce it to survive
treatment with -lactam antimicrobial drugs.
C. 95% of nosocomial S. aureus isolates produce beta-
lactamase (penicillinase). |
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Term
|
Definition
STAPH:kill a variety of cells by disrupting their
cytoplasmic membrane. |
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Term
|
Definition
STAPH:lyses leukocytes specifically, and is distinct from
the α, β, γ and δ cytolytic exotoxins. |
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Term
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Definition
STAPH:destroy desmosomes (the structures that hold
adjoining cells together), causing skin cells to
separate from each other and slough off the body. |
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Term
|
Definition
STAPH:Toxic-shock-
syndrome toxin
and Enterotoxins(also in food poisoing |
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