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14 Cilia and Flagella
powerpoint lecture
25
Biology
Undergraduate 1
03/06/2011

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Cards

Term
How do flagella propel cells?
Definition
using repetitive wavelike motion
Term
Explain the ultrastructure that cilia and flagellum have in common
Definition

-a core of microtubules sheathed by the plasma membrane

- a basal body that anchors the cilium or flagellum

- a motor protein called dynein

Term
What doe the motor protein dynein do?
Definition
drives the bending movement of the cilium or flagellum
Term
9+2 arrangement
Definition
Microtubules in a cilium or flagellum are arranged in a 9+2 array. the nine outer microtubules carry two rows of dynein molecules 
Term
How does dynein cause movement in microtubule doublets?
Definition

the dynein arms of one microtubule doublet grip the adjacent doublet, push it up, release, and then grip again.


If the two microtubule doublets were not attached, they would slide relative to each other 

 


Term
Explain how dynein causes movement in normal cilium and flagellum
Definition
two adjacent doublets cannot slide far because they are physically restrained by proteins so they bend
Term
What is the structural role of microfilaments?
Definition
to bear tension and resist pulling forces within the cell
Term

What is the 3-D network called that is created by Microfilaments?

where is it and what does it do?

Definition

the cortex

it is just inside the plasma membrane

it helps support the cell's shape 

Term
Microfilaments that function in cell motility contain a protein other than actin. What is it?
Definition
myosin
Term
What is amoeboid movement?
Definition
Amoeboid movement is a crawling-like type of movement accomplished by protrusion of microfilaments in the cytoplasm of the cell involving the formation of pseudopodia. The cytoplasm slides and forms a pseudopodium in front to move the cell forward.
Term
Pseudopodia
Definition

(cellular extensions)

extend and contract through reversible assembly and contraction of actin subunits into microfilaments

Term
How do the bundles of long fibers run in skeletal muscles?
Definition
they run parallel to the length of the muscle
Term
What does a muscle fiber contain?
Definition
bundles of smaller myofibrils arranged longitudinally
Term
What is a vertebrate skeletal muscle characterized by?
Definition
a hierarchy of smaller and smaller units
Term
What type of filaments are myofibrils composed of?
Definition

thin filaments (2 strands of actin, one strand of regulatory)

Thick filaments (staggered arrays of myosin molecules)

Term
What is another name for striated muscle?
Definition
skeletal muscle 
Term
Sacromere 
Definition
the contractile unit of a myofibril; sarcomeres are repeating units, delimited by the Z bands along the length of the myofibril.
Term
What borders the sarcomeres?
Definition
z line
Term
What do the myofilaments contain?
Definition
I band, A band and H zone
Term
When the filaments slide past each other longitudinally, what happens?
Definition
the I bands and H zone shrink
Term
What causes the sliding of the filaments?
Definition

interaction between the actin and myosin molecules of the thick and thin filaments

Term
When is the only time a muscle fiber will contract?
Definition
only when stimulated by a motor neuron
Term

When a muscle is at rest the myosin-binding sites on the thin filament are blocked by the regulatory protein ____.

 

Definition
tropomyosin
Term
What causes the myosin-binding sites to be uncovered
Definition
Calcium ions (Ca2+) bind to another set of regulatory proteins, the troponin complex
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