Term
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Definition
1 in 50 Caucasians born in the US in 2010 is projected to develop invasive melanoma over their lifetime
the most common type of cancer in young US adults age 25-29 |
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Term
| melanoma in dark-pigmented persons |
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Definition
melanoma is relatively uncommon in African Americans, Hispanics and Asians
more deadly in these due to late detection
tumors usually arise on the palms, soles, mucous membranes, and nail regions |
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Term
| the ABCDs of skin markings |
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Definition
A:symmetry
B:order
C:olor
D:ifference
-overtime
-in relation to other markings |
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Term
| factors determining prognosis |
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Definition
tumor thickness is measured in millimeters
Breslow depth = from granular later to bottom of tumor
single most important independent factor of the primary lesion in determining treatment, FU, prognosis
>1mm increased risk of metastasis to lymph node |
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Term
| sentinel lymph node biopsy |
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Definition
sentinel node = the first LN receiving direct lymphatic drainage from a cancer site
represents the a potential first-site to contain metastatic cancer cells
selective removal of the SLN with careful histologic examination is accurate and reliable to detect micromatastases and therefore stage the entire nodal basin |
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